BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 21990608)

  • 1. The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination.
    Brim RL; Noon KR; Collins GT; Stein A; Nichols J; Narasimhan D; Ko MC; Woods JH; Sunahara RK
    J Pharmacol Exp Ther; 2012 Jan; 340(1):83-95. PubMed ID: 21990608
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ability of bacterial cocaine esterase to hydrolyze cocaine metabolites and their simultaneous quantification using high-performance liquid chromatography-tandem mass spectrometry.
    Brim RL; Noon KR; Collins GT; Nichols J; Narasimhan D; Sunahara RK; Woods JH
    Mol Pharmacol; 2011 Dec; 80(6):1119-27. PubMed ID: 21885621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats.
    Collins GT; Brim RL; Narasimhan D; Ko MC; Sunahara RK; Zhan CG; Woods JH
    J Pharmacol Exp Ther; 2009 Nov; 331(2):445-55. PubMed ID: 19710369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of the hydrolytic activity of a long-acting mutant bacterial cocaine in the presence of commonly co-administered drugs.
    Brim RL; Noon KR; Nichols J; Narasimhan D; Woods JH; Sunahara RK
    Drug Alcohol Depend; 2011 Dec; 119(3):224-8. PubMed ID: 21775073
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats.
    Collins GT; Zaks ME; Cunningham AR; St Clair C; Nichols J; Narasimhan D; Ko MC; Sunahara RK; Woods JH
    Drug Alcohol Depend; 2011 Nov; 118(2-3):158-65. PubMed ID: 21481548
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase.
    Collins GT; Carey KA; Narasimhan D; Nichols J; Berlin AA; Lukacs NW; Sunahara RK; Woods JH; Ko MC
    Neuropsychopharmacology; 2011 Apr; 36(5):1047-59. PubMed ID: 21289605
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys.
    Collins GT; Brim RL; Noon KR; Narasimhan D; Lukacs NW; Sunahara RK; Woods JH; Ko MC
    J Pharmacol Exp Ther; 2012 Jul; 342(1):205-13. PubMed ID: 22518021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.
    Cooper ZD; Narasimhan D; Sunahara RK; Mierzejewski P; Jutkiewicz EM; Larsen NA; Wilson IA; Landry DW; Woods JH
    Mol Pharmacol; 2006 Dec; 70(6):1885-91. PubMed ID: 16968810
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
    Brim RL; Nance MR; Youngstrom DW; Narasimhan D; Zhan CG; Tesmer JJ; Sunahara RK; Woods JH
    Mol Pharmacol; 2010 Apr; 77(4):593-600. PubMed ID: 20086035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
    Collins GT; Narasimhan D; Cunningham AR; Zaks ME; Nichols J; Ko MC; Sunahara RK; Woods JH
    Neuropsychopharmacology; 2012 Apr; 37(5):1092-103. PubMed ID: 21993206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
    Narasimhan D; Collins GT; Nance MR; Nichols J; Edwald E; Chan J; Ko MC; Woods JH; Tesmer JJ; Sunahara RK
    Mol Pharmacol; 2011 Dec; 80(6):1056-65. PubMed ID: 21890748
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates.
    Howell LL; Nye JA; Stehouwer JS; Voll RJ; Mun J; Narasimhan D; Nichols J; Sunahara R; Goodman MM; Carroll FI; Woods JH
    Transl Psychiatry; 2014 Jul; 4(7):e407. PubMed ID: 24984194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biochemical characterization and structural analysis of a highly proficient cocaine esterase.
    Turner JM; Larsen NA; Basran A; Barbas CF; Bruce NC; Wilson IA; Lerner RA
    Biochemistry; 2002 Oct; 41(41):12297-307. PubMed ID: 12369817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats.
    Wood SK; Narasimhan D; Cooper Z; Sunahara RK; Woods JH
    Drug Alcohol Depend; 2010 Jan; 106(2-3):219-29. PubMed ID: 19800183
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.
    Gao D; Narasimhan DL; Macdonald J; Brim R; Ko MC; Landry DW; Woods JH; Sunahara RK; Zhan CG
    Mol Pharmacol; 2009 Feb; 75(2):318-23. PubMed ID: 18987161
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction.
    Narasimhan D; Woods JH; Sunahara RK
    Future Med Chem; 2012 Feb; 4(2):137-50. PubMed ID: 22300094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reaction mechanism for cocaine esterase-catalyzed hydrolyses of (+)- and (-)-cocaine: unexpected common rate-determining step.
    Liu J; Zhao X; Yang W; Zhan CG
    J Phys Chem B; 2011 May; 115(17):5017-25. PubMed ID: 21486046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cocaine esterase: interactions with cocaine and immune responses in mice.
    Ko MC; Bowen LD; Narasimhan D; Berlin AA; Lukacs NW; Sunahara RK; Cooper ZD; Woods JH
    J Pharmacol Exp Ther; 2007 Feb; 320(2):926-33. PubMed ID: 17114567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats.
    Gao Y; Brimijoin S
    Chem Biol Interact; 2005 Dec; 157-158():97-103. PubMed ID: 16243302
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural analysis of thermostabilizing mutations of cocaine esterase.
    Narasimhan D; Nance MR; Gao D; Ko MC; Macdonald J; Tamburi P; Yoon D; Landry DM; Woods JH; Zhan CG; Tesmer JJ; Sunahara RK
    Protein Eng Des Sel; 2010 Jul; 23(7):537-47. PubMed ID: 20436035
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.