BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 21990614)

  • 1. Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.
    Baughn LB; Kalis SL; MacCarthy T; Wei L; Fan M; Bergman A; Scharff MD
    mBio; 2011; 2(5):. PubMed ID: 21990614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes.
    Duan Z; Baughn LB; Wang X; Zhang Y; Gupta V; MacCarthy T; Scharff MD; Yu G
    Proc Natl Acad Sci U S A; 2021 Jul; 118(29):. PubMed ID: 34253616
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.
    Zhang W; Bardwell PD; Woo CJ; Poltoratsky V; Scharff MD; Martin A
    Int Immunol; 2001 Sep; 13(9):1175-84. PubMed ID: 11526098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
    Chezar I; Lobel-Lavi L; Steinitz M; Laskov R
    Mol Immunol; 2008 Nov; 46(1):80-90. PubMed ID: 18718665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coupling recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells.
    Chen C; Li N; Zhao Y; Hang H
    Biotechnol Bioeng; 2016 Jan; 113(1):39-51. PubMed ID: 26235363
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Assessing somatic hypermutation in Ramos B cells after overexpression or knockdown of specific genes.
    Upton DC; Unniraman S
    J Vis Exp; 2011 Nov; (57):e3573. PubMed ID: 22083360
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes.
    Tang C; MacCarthy T
    Front Immunol; 2021; 12():671944. PubMed ID: 34040612
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes.
    Tang C; Bagnara D; Chiorazzi N; Scharff MD; MacCarthy T
    Front Immunol; 2020; 11():788. PubMed ID: 32425948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
    Schrader CE; Linehan EK; Ucher AJ; Bertocci B; Stavnezer J
    DNA Repair (Amst); 2013 Dec; 12(12):1087-93. PubMed ID: 24084171
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3' activation-induced cytidine deaminase target.
    Ohm-Laursen L; Barington T
    J Immunol; 2007 Apr; 178(7):4322-34. PubMed ID: 17371989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overlapping hotspots in CDRs are critical sites for V region diversification.
    Wei L; Chahwan R; Wang S; Wang X; Pham PT; Goodman MF; Bergman A; Scharff MD; MacCarthy T
    Proc Natl Acad Sci U S A; 2015 Feb; 112(7):E728-37. PubMed ID: 25646473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.
    Komori A; Xu Z; Wu X; Zan H; Casali P
    Mol Immunol; 2006 Apr; 43(11):1817-26. PubMed ID: 16412510
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region.
    Pan-Hammarström Q; Dai S; Zhao Y; van Dijk-Härd IF; Gatti RA; Børresen-Dale AL; Hammarström L
    J Immunol; 2003 Apr; 170(7):3707-16. PubMed ID: 12646636
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic hypermutation of the AID transgene in B and non-B cells.
    Martin A; Scharff MD
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12304-8. PubMed ID: 12202747
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells.
    Ronai D; Iglesias-Ussel MD; Fan M; Shulman MJ; Scharff MD
    Proc Natl Acad Sci U S A; 2005 Aug; 102(33):11829-34. PubMed ID: 16087866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutation.
    Scherer F; Navarrete MA; Bertinetti-Lapatki C; Boehm J; Schmitt-Graeff A; Veelken H
    Leuk Lymphoma; 2016; 57(1):151-60. PubMed ID: 25860234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line.
    Bemark M; Neuberger MS
    Oncogene; 2000 Jul; 19(30):3404-10. PubMed ID: 10918597
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line.
    Lerner LK; Bonte D; Le Guillou M; Mohammad MM; Kasraian Z; Sarasin A; Despras E; Aoufouchi S
    Front Immunol; 2022; 13():871766. PubMed ID: 35432321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate.
    Ruiz JF; Lucas D; García-Palomero E; Saez AI; González MA; Piris MA; Bernad A; Blanco L
    Nucleic Acids Res; 2004; 32(19):5861-73. PubMed ID: 15520469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. What do somatic hypermutation and class switch recombination teach us about chronic lymphocytic leukaemia pathogenesis?
    Oppezzo P; Dighiero G
    Curr Top Microbiol Immunol; 2005; 294():71-89. PubMed ID: 16323428
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.