85 related articles for article (PubMed ID: 2199133)
1. Effects of the ACAT inhibitor CL 277,082 on cholesterol metabolism in humans.
Harris WS; Dujovne CA; von Bergmann K; Neal J; Akester J; Windsor SL; Greene D; Look Z
Clin Pharmacol Ther; 1990 Aug; 48(2):189-94. PubMed ID: 2199133
[TBL] [Abstract][Full Text] [Related]
2. Divergent pharmacologic activities of PD 132301-2 and CL 277,082, urea inhibitors of acyl-CoA:cholesterol acyltransferase.
Krause BR; Black A; Bousley R; Essenburg A; Cornicelli J; Holmes A; Homan R; Kieft K; Sekerke C; Shaw-Hes MK
J Pharmacol Exp Ther; 1993 Nov; 267(2):734-43. PubMed ID: 8246149
[TBL] [Abstract][Full Text] [Related]
3. On the mechanism by which an ACAT inhibitor (CL 277,082) influences plasma lipoproteins in the rat.
Balasubramaniam S; Simons LA; Chang S; Roach PD; Nestel PJ
Atherosclerosis; 1990 May; 82(1-2):1-5. PubMed ID: 2360913
[TBL] [Abstract][Full Text] [Related]
4. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters.
Sugiyama Y; Ishikawa E; Odaka H; Miki N; Tawada H; Ikeda H
Atherosclerosis; 1995 Feb; 113(1):71-8. PubMed ID: 7755657
[TBL] [Abstract][Full Text] [Related]
5. Effect of the ACAT inhibitor CL 277,082 on apolipoprotein B48 transport in mesenteric lymph and on plasma clearance of chylomicrons and remnants.
Martins IJ; Mortimer BC; Redgrave TG
Arterioscler Thromb Vasc Biol; 1997 Jan; 17(1):211-6. PubMed ID: 9012658
[TBL] [Abstract][Full Text] [Related]
6. ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys.
Wrenn SM; Parks JS; Immermann FW; Rudel LL
J Lipid Res; 1995 Jun; 36(6):1199-210. PubMed ID: 7665998
[TBL] [Abstract][Full Text] [Related]
7. CL 277,082: a novel inhibitor of ACAT-catalyzed cholesterol esterification and cholesterol absorption.
Largis EE; Wang CH; DeVries VG; Schaffer SA
J Lipid Res; 1989 May; 30(5):681-90. PubMed ID: 2760542
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs.
Kashiwa M; Masuyama Y; Miyauchi H; Uchida T; Naganuma S; Kakuta H; Terada M; Kiriyama T; Matsuda K; Ito N; Iizumi Y; Takenaka T
Jpn J Pharmacol; 1997 Jan; 73(1):41-50. PubMed ID: 9032133
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity.
Sliskovic DR; Krause BR; Picard JA; Anderson M; Bousley RF; Hamelehle KL; Homan R; Julian TN; Rashidbaigi ZA; Stanfield RL
J Med Chem; 1994 Mar; 37(5):560-2. PubMed ID: 8126693
[No Abstract] [Full Text] [Related]
10. Relationship between bioavailability and hypocholesterolemic activity of YM17E, an inhibitor of ACAT, in cholesterol-fed rats.
Uchida T; Aoyama K; Watanabe T; Higuchi S
Atherosclerosis; 1998 Mar; 137(1):97-106. PubMed ID: 9568741
[TBL] [Abstract][Full Text] [Related]
11. Effects of acyl-CoA: cholesterol O-acyltransferase inhibition on cholesterol absorption and plasma lipoprotein composition in hamsters.
Schnitzer-Polokoff R; Compton D; Boykow G; Davis H; Burrier R
Comp Biochem Physiol A Comp Physiol; 1991; 99(4):665-70. PubMed ID: 1679704
[TBL] [Abstract][Full Text] [Related]
12. Novel acyl-CoA:cholesterol acyltransferase inhibitors. Synthesis and biological activity of 3-quinolylurea derivatives.
Tawada H; Harcourt M; Kawamura N; Kajino M; Ishikawa E; Sugiyama Y; Ikeda H; Meguro K
J Med Chem; 1994 Jun; 37(13):2079-84. PubMed ID: 8027989
[TBL] [Abstract][Full Text] [Related]
13. TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters.
Sugiyama Y; Odaka H; Itokawa S; Ishikawa E; Tomari Y; Ikeda H
Atherosclerosis; 1995 Nov; 118(1):145-53. PubMed ID: 8579624
[TBL] [Abstract][Full Text] [Related]
14. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.
Trivedi BK; Purchase TS; Holmes A; Augelli-Szafran CE; Essenburg AD; Hamelehle KL; Stanfield RL; Bousley RF; Krause BR
J Med Chem; 1994 May; 37(11):1652-9. PubMed ID: 8201599
[TBL] [Abstract][Full Text] [Related]
15. The tolerability, pharmacokinetics and lack of effect on plasma cholesterol of 447C88, an AcylCoA: Cholesterol Acyl Transferase (ACAT) inhibitor with low bioavailability, in healthy volunteers.
Peck RW; Wiggs R; Posner J
Eur J Clin Pharmacol; 1995; 49(3):243-9. PubMed ID: 8666002
[TBL] [Abstract][Full Text] [Related]
16. Regulation of ovarian cholesterol metabolism: control of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase.
Schuler LA; Toaff ME; Strauss JF
Endocrinology; 1981 Apr; 108(4):1476-86. PubMed ID: 7472277
[TBL] [Abstract][Full Text] [Related]
17. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
[TBL] [Abstract][Full Text] [Related]
18. Role of the intestinal acyl-CoA:cholesterol acyltransferase activity in the hyperresponse of diabetic rats to dietary cholesterol.
Maechler P; Wollheim CB; Bentzen CL; Niesor E
J Lipid Res; 1992 Oct; 33(10):1475-84. PubMed ID: 1431572
[TBL] [Abstract][Full Text] [Related]
19. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond.
Roark WH; Roth BD; Holmes A; Trivedi BK; Kieft KA; Essenburg AD; Krause BR; Stanfield RL
J Med Chem; 1993 May; 36(11):1662-8. PubMed ID: 8496932
[TBL] [Abstract][Full Text] [Related]
20. Effect of the acyl-CoA:cholesterol acyltransferase inhibitor DuP 128 on cholesterol absorption and serum cholesterol in humans.
Hainer JW; Terry JG; Connell JM; Zyruk H; Jenkins RM; Shand DL; Gillies PJ; Livak KJ; Hunt TL; Crouse JR
Clin Pharmacol Ther; 1994 Jul; 56(1):65-74. PubMed ID: 8033496
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]