142 related articles for article (PubMed ID: 21994236)
1. Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes.
Ayed-Boussema I; Pascussi JM; Maurel P; Bacha H; Hassen W
Int J Toxicol; 2012; 31(1):86-93. PubMed ID: 21994236
[TBL] [Abstract][Full Text] [Related]
2. Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes.
Ayed-Boussema I; Pascussi JM; Maurel P; Bacha H; Hassen W
Environ Toxicol Pharmacol; 2011 Jan; 31(1):79-87. PubMed ID: 21787672
[TBL] [Abstract][Full Text] [Related]
3. Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors.
Ayed-Boussema I; Pascussi JM; Zaied C; Maurel P; Bacha H; Hassen W
Drug Chem Toxicol; 2012 Jan; 35(1):71-80. PubMed ID: 21834667
[TBL] [Abstract][Full Text] [Related]
4. The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes.
Ayed-Boussema I; Pascussi JM; Rjiba K; Maurel P; Bacha H; Hassen W
Drug Chem Toxicol; 2012 Jul; 35(3):241-50. PubMed ID: 21939362
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
Westerink WM; Schoonen WG
Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
[TBL] [Abstract][Full Text] [Related]
6. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
Vrzal R; Kubesova K; Pavek P; Dvorak Z
Toxicol Lett; 2010 Mar; 193(2):183-8. PubMed ID: 20080160
[TBL] [Abstract][Full Text] [Related]
7. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C; Daujat-Chavanieu M; Pascussi JM; Pichard-Garcia L; Balaguer P; Fabre JM; Vilarem MJ; Maurel P; Gerbal-Chaloin S
Mol Pharmacol; 2006 Jul; 70(1):329-39. PubMed ID: 16608920
[TBL] [Abstract][Full Text] [Related]
8. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
Hariparsad N; Carr BA; Evers R; Chu X
Drug Metab Dispos; 2008 Jun; 36(6):1046-55. PubMed ID: 18332078
[TBL] [Abstract][Full Text] [Related]
9. Induction of CYP2C genes in human hepatocytes in primary culture.
Gerbal-Chaloin S; Pascussi JM; Pichard-Garcia L; Daujat M; Waechter F; Fabre JM; Carrère N; Maurel P
Drug Metab Dispos; 2001 Mar; 29(3):242-51. PubMed ID: 11181490
[TBL] [Abstract][Full Text] [Related]
10. Non-coplanar and coplanar polychlorinated biphenyls potentiate genotoxicity of aflatoxin B1 in a human hepatocyte line by enhancing CYP1A2 and CYP3A4 expression.
Chen Y; Liu Y
Environ Pollut; 2019 Mar; 246():945-954. PubMed ID: 31159144
[TBL] [Abstract][Full Text] [Related]
11. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
Dvorák Z; Maurel P; Vilarem MJ; Ulrichová J; Modrianský M
Cell Biol Toxicol; 2007 Mar; 23(2):63-73. PubMed ID: 16964586
[TBL] [Abstract][Full Text] [Related]
12. Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.
Bachleda P; Vrzal R; Pivnicka J; Cvek B; Dvorak Z
Toxicol Lett; 2009 Dec; 191(1):74-8. PubMed ID: 19686824
[TBL] [Abstract][Full Text] [Related]
13. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
Aninat C; Piton A; Glaise D; Le Charpentier T; Langouët S; Morel F; Guguen-Guillouzo C; Guillouzo A
Drug Metab Dispos; 2006 Jan; 34(1):75-83. PubMed ID: 16204462
[TBL] [Abstract][Full Text] [Related]
14. Environmental pollutants parathion, paraquat and bisphenol A show distinct effects towards nuclear receptors-mediated induction of xenobiotics-metabolizing cytochromes P450 in human hepatocytes.
Vrzal R; Zenata O; Doricakova A; Dvorak Z
Toxicol Lett; 2015 Oct; 238(1):43-53. PubMed ID: 26196221
[TBL] [Abstract][Full Text] [Related]
15. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
[TBL] [Abstract][Full Text] [Related]
16. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
[TBL] [Abstract][Full Text] [Related]
17. Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes.
Stepankova M; Pastorkova B; Bachleda P; Dvorak Z
Toxicology; 2017 May; 383():40-49. PubMed ID: 28390928
[TBL] [Abstract][Full Text] [Related]
18. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
Cheng X; Maher J; Dieter MZ; Klaassen CD
Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
[TBL] [Abstract][Full Text] [Related]
19. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
Guillouzo A; Corlu A; Aninat C; Glaise D; Morel F; Guguen-Guillouzo C
Chem Biol Interact; 2007 May; 168(1):66-73. PubMed ID: 17241619
[TBL] [Abstract][Full Text] [Related]
20. TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes.
Matsuoka-Kawano K; Yoshinari K; Nagayama S; Yamazoe Y
Chem Biol Interact; 2010 Apr; 185(1):33-41. PubMed ID: 20171196
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
