202 related articles for article (PubMed ID: 21994799)
21. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
Wu Y; Koharudin LMI; Mehrens J; DeLucia M; Byeon CH; Byeon IL; Calero G; Ahn J; Gronenborn AM
J Biol Chem; 2015 Jul; 290(29):17935-17945. PubMed ID: 26045556
[TBL] [Abstract][Full Text] [Related]
22. Functional analysis of the relationship between Vpx and the restriction factor SAMHD1.
Berger G; Turpin J; Cordeil S; Tartour K; Nguyen XN; Mahieux R; Cimarelli A
J Biol Chem; 2012 Nov; 287(49):41210-7. PubMed ID: 23076149
[TBL] [Abstract][Full Text] [Related]
23. SAMHD1: a new insight into HIV-1 restriction in myeloid cells.
St Gelais C; Wu L
Retrovirology; 2011 Jul; 8():55. PubMed ID: 21740548
[TBL] [Abstract][Full Text] [Related]
24. Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.
Goujon C; Arfi V; Pertel T; Luban J; Lienard J; Rigal D; Darlix JL; Cimarelli A
J Virol; 2008 Dec; 82(24):12335-45. PubMed ID: 18829761
[TBL] [Abstract][Full Text] [Related]
25. Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels.
Amie SM; Daly MB; Noble E; Schinazi RF; Bambara RA; Kim B
J Biol Chem; 2013 Jul; 288(28):20683-91. PubMed ID: 23744077
[TBL] [Abstract][Full Text] [Related]
26. HIV-2 Vpx neutralizes host restriction factor SAMHD1 to promote viral pathogenesis.
Mohamed A; Bakir T; Al-Hawel H; Al-Sharif I; Bakheet R; Kouser L; Murugaiah V; Al-Mozaini M
Sci Rep; 2021 Oct; 11(1):20984. PubMed ID: 34697376
[TBL] [Abstract][Full Text] [Related]
27. Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.
Reinhard C; Bottinelli D; Kim B; Luban J
Retrovirology; 2014 Feb; 11():12. PubMed ID: 24485168
[TBL] [Abstract][Full Text] [Related]
28. Moderate restriction of macrophage-tropic human immunodeficiency virus type 1 by SAMHD1 in monocyte-derived macrophages.
Taya K; Nakayama EE; Shioda T
PLoS One; 2014; 9(3):e90969. PubMed ID: 24599229
[TBL] [Abstract][Full Text] [Related]
29. The ribonuclease activity of SAMHD1 is required for HIV-1 restriction.
Ryoo J; Choi J; Oh C; Kim S; Seo M; Kim SY; Seo D; Kim J; White TE; Brandariz-Nuñez A; Diaz-Griffero F; Yun CH; Hollenbaugh JA; Kim B; Baek D; Ahn K
Nat Med; 2014 Aug; 20(8):936-41. PubMed ID: 25038827
[TBL] [Abstract][Full Text] [Related]
30. SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons.
St Gelais C; de Silva S; Amie SM; Coleman CM; Hoy H; Hollenbaugh JA; Kim B; Wu L
Retrovirology; 2012 Dec; 9():105. PubMed ID: 23231760
[TBL] [Abstract][Full Text] [Related]
31. Viral protein X reduces the incorporation of mutagenic noncanonical rNTPs during lentivirus reverse transcription in macrophages.
Oo A; Kim DH; Schinazi RF; Kim B
J Biol Chem; 2020 Jan; 295(2):657-666. PubMed ID: 31806704
[TBL] [Abstract][Full Text] [Related]
32. Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.
Sunseri N; O'Brien M; Bhardwaj N; Landau NR
J Virol; 2011 Jul; 85(13):6263-74. PubMed ID: 21507971
[TBL] [Abstract][Full Text] [Related]
33. HIV type 1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 and cannot be counteracted by Vpx.
Bloch N; O'Brien M; Norton TD; Polsky SB; Bhardwaj N; Landau NR
AIDS Res Hum Retroviruses; 2014 Feb; 30(2):195-203. PubMed ID: 23924154
[TBL] [Abstract][Full Text] [Related]
34. Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor.
Zhang C; de Silva S; Wang JH; Wu L
PLoS One; 2012; 7(5):e37477. PubMed ID: 22574228
[TBL] [Abstract][Full Text] [Related]
35. SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells.
Puigdomènech I; Casartelli N; Porrot F; Schwartz O
J Virol; 2013 Mar; 87(5):2846-56. PubMed ID: 23269793
[TBL] [Abstract][Full Text] [Related]
36. SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.
Ballana E; Badia R; Terradas G; Torres-Torronteras J; Ruiz A; Pauls E; Riveira-Muñoz E; Clotet B; Martí R; Esté JA
Antimicrob Agents Chemother; 2014 Aug; 58(8):4804-13. PubMed ID: 24913159
[TBL] [Abstract][Full Text] [Related]
37. Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus.
Spragg CJ; Emerman M
Proc Natl Acad Sci U S A; 2013 Dec; 110(52):21136-41. PubMed ID: 24324150
[TBL] [Abstract][Full Text] [Related]
38. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.
Lahouassa H; Daddacha W; Hofmann H; Ayinde D; Logue EC; Dragin L; Bloch N; Maudet C; Bertrand M; Gramberg T; Pancino G; Priet S; Canard B; Laguette N; Benkirane M; Transy C; Landau NR; Kim B; Margottin-Goguet F
Nat Immunol; 2012 Feb; 13(3):223-228. PubMed ID: 22327569
[TBL] [Abstract][Full Text] [Related]
39. Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1.
Li J; Xu F; Hu S; Zhou J; Mei S; Zhao X; Cen S; Jin Q; Liang C; Guo F
Biochem J; 2015 Jun; 468(2):303-13. PubMed ID: 25791246
[TBL] [Abstract][Full Text] [Related]
40. SAMHD1 in Retroviral Restriction and Innate Immune Sensing--Should We Leash the Hound?
Herrmann A; Happel AU; Gramberg T
Curr HIV Res; 2016; 14(3):225-34. PubMed ID: 26957197
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
