241 related articles for article (PubMed ID: 21996738)
1. Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.
Feng H; Liu KW; Guo P; Zhang P; Cheng T; McNiven MA; Johnson GR; Hu B; Cheng SY
Oncogene; 2012 May; 31(21):2691-702. PubMed ID: 21996738
[TBL] [Abstract][Full Text] [Related]
2. SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.
Zhang L; Zhang W; Li Y; Alvarez A; Li Z; Wang Y; Song L; Lv D; Nakano I; Hu B; Cheng SY; Feng H
Oncogene; 2016 Oct; 35(43):5641-5652. PubMed ID: 27041571
[TBL] [Abstract][Full Text] [Related]
3. SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans.
Liu KW; Feng H; Bachoo R; Kazlauskas A; Smith EM; Symes K; Hamilton RL; Nagane M; Nishikawa R; Hu B; Cheng SY
J Clin Invest; 2011 Mar; 121(3):905-17. PubMed ID: 21393858
[TBL] [Abstract][Full Text] [Related]
4. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
Feng H; Hu B; Liu KW; Li Y; Lu X; Cheng T; Yiin JJ; Lu S; Keezer S; Fenton T; Furnari FB; Hamilton RL; Vuori K; Sarkaria JN; Nagane M; Nishikawa R; Cavenee WK; Cheng SY
J Clin Invest; 2011 Dec; 121(12):4670-84. PubMed ID: 22080864
[TBL] [Abstract][Full Text] [Related]
5. Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.
Feng H; Li Y; Yin Y; Zhang W; Hou Y; Zhang L; Li Z; Xie B; Gao WQ; Sarkaria JN; Raizer JJ; James CD; Parsa AT; Hu B; Cheng SY
Neuro Oncol; 2015 Jun; 17(6):832-42. PubMed ID: 25468898
[TBL] [Abstract][Full Text] [Related]
6. Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics.
Keum S; Yang SJ; Park E; Kang T; Choi JH; Jeong J; Hwang YE; Kim JW; Park D; Rhee S
Cell Oncol (Dordr); 2021 Dec; 44(6):1287-1305. PubMed ID: 34582006
[TBL] [Abstract][Full Text] [Related]
7. Targeting PDGFRα-activated glioblastoma through specific inhibition of SHP-2-mediated signaling.
Sang Y; Hou Y; Cheng R; Zheng L; Alvarez AA; Hu B; Cheng SY; Zhang W; Li Y; Feng H
Neuro Oncol; 2019 Nov; 21(11):1423-1435. PubMed ID: 31232447
[TBL] [Abstract][Full Text] [Related]
8. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors.
Wu CJ; O'Rourke DM; Feng GS; Johnson GR; Wang Q; Greene MI
Oncogene; 2001 Sep; 20(42):6018-25. PubMed ID: 11593409
[TBL] [Abstract][Full Text] [Related]
9. Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells.
Kapoor GS; Zhan Y; Johnson GR; O'Rourke DM
Mol Cell Biol; 2004 Jan; 24(2):823-36. PubMed ID: 14701753
[TBL] [Abstract][Full Text] [Related]
10. Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
Eppinga RD; Krueger EW; Weller SG; Zhang L; Cao H; McNiven MA
Oncogene; 2012 Mar; 31(10):1228-41. PubMed ID: 21841817
[TBL] [Abstract][Full Text] [Related]
11. Targeting the yin and the yang: combined inhibition of the tyrosine kinase c-Src and the tyrosine phosphatase SHP-2 disrupts pancreatic cancer signaling and biology in vitro and tumor formation in vivo.
Gomes EG; Connelly SF; Summy JM
Pancreas; 2013 Jul; 42(5):795-806. PubMed ID: 23271399
[TBL] [Abstract][Full Text] [Related]
12. Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation.
Madarampalli B; Watts GFM; Panipinto PM; Nguygen HN; Brenner MB; Noss EH
Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1516-1524. PubMed ID: 30876808
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation.
Bazenet CE; Gelderloos JA; Kazlauskas A
Mol Cell Biol; 1996 Dec; 16(12):6926-36. PubMed ID: 8943348
[TBL] [Abstract][Full Text] [Related]
14. Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase.
Ohkawa Y; Momota H; Kato A; Hashimoto N; Tsuda Y; Kotani N; Honke K; Suzumura A; Furukawa K; Ohmi Y; Natsume A; Wakabayashi T; Furukawa K
J Biol Chem; 2015 Jun; 290(26):16043-58. PubMed ID: 25940087
[TBL] [Abstract][Full Text] [Related]
15. Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells.
Lei H; Kazlauskas A
J Biol Chem; 2009 Mar; 284(10):6329-36. PubMed ID: 19126548
[TBL] [Abstract][Full Text] [Related]
16. HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation.
Cobbs C; Khan S; Matlaf L; McAllister S; Zider A; Yount G; Rahlin K; Harkins L; Bezrookove V; Singer E; Soroceanu L
Oncotarget; 2014 Feb; 5(4):1091-100. PubMed ID: 24658280
[TBL] [Abstract][Full Text] [Related]
17. Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.
Fortin SP; Ennis MJ; Schumacher CA; Zylstra-Diegel CR; Williams BO; Ross JT; Winkles JA; Loftus JC; Symons MH; Tran NL
Mol Cancer Res; 2012 Jul; 10(7):958-68. PubMed ID: 22571869
[TBL] [Abstract][Full Text] [Related]
18. The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.
Noël LA; Arts FA; Montano-Almendras CP; Cox L; Gielen O; Toffalini F; Marbehant CY; Cools J; Demoulin JB
Mol Oncol; 2014 May; 8(3):728-40. PubMed ID: 24618081
[TBL] [Abstract][Full Text] [Related]
19. Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways.
Park CM; Park MJ; Kwak HJ; Lee HC; Kim MS; Lee SH; Park IC; Rhee CH; Hong SI
Cancer Res; 2006 Sep; 66(17):8511-9. PubMed ID: 16951163
[TBL] [Abstract][Full Text] [Related]
20. Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.
Kwon M; Ling Y; Maile LA; Badley-Clark J; Clemmons DR
Endocrinology; 2006 Mar; 147(3):1458-65. PubMed ID: 16306077
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
