BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 21996745)

  • 1. Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo.
    Manser C; Guillot F; Vagnoni A; Davies J; Lau KF; McLoughlin DM; De Vos KJ; Miller CC
    Oncogene; 2012 May; 31(22):2773-82. PubMed ID: 21996745
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lemur tyrosine kinase 2 acts as a positive regulator of NF-κB activation and colon cancer cell proliferation.
    Zhang R; Li X; Wei L; Qin Y; Fang J
    Cancer Lett; 2019 Jul; 454():70-77. PubMed ID: 30980866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.
    Hoover LL; Burton EG; O'Neill ML; Brooks BA; Sreedharan S; Dawson NA; Kubalak SW
    Biochim Biophys Acta; 2008 Dec; 1783(12):2279-86. PubMed ID: 18773928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Requirement of a dynein light chain in TGFbeta/Smad3 signaling.
    Jin Q; Gao G; Mulder KM
    J Cell Physiol; 2009 Dec; 221(3):707-15. PubMed ID: 19711352
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.
    Kamato D; Burch ML; Piva TJ; Rezaei HB; Rostam MA; Xu S; Zheng W; Little PJ; Osman N
    Cell Signal; 2013 Oct; 25(10):2017-24. PubMed ID: 23770288
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.
    Nakano N; Maeyama K; Sakata N; Itoh F; Akatsu R; Nakata M; Katsu Y; Ikeno S; Togawa Y; Vo Nguyen TT; Watanabe Y; Kato M; Itoh S
    J Biol Chem; 2014 May; 289(18):12680-92. PubMed ID: 24627487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains.
    Mórotz GM; Glennon EB; Gomez-Suaga P; Lau DHW; Robinson ED; Sedlák É; Vagnoni A; Noble W; Miller CCJ
    Acta Neuropathol Commun; 2019 May; 7(1):73. PubMed ID: 31068217
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members.
    Conti A; Majorini MT; Fontanella E; Bardelli A; Giacca M; Delia D; Mano M; Lecis D
    Cancer Lett; 2017 Mar; 389():59-69. PubMed ID: 28040547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lemur tyrosine kinase 2 silencing inhibits the proliferation of gastric cancer cells by regulating GSK-3β phosphorylation and β-catenin nuclear translocation.
    Han X; Wang DZ; Yuan M; Bai WJ
    Bioengineered; 2022 Mar; 13(3):6231-6243. PubMed ID: 34719320
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silencing of lemur tyrosine kinase 2 restricts the proliferation and invasion of hepatocellular carcinoma through modulation of GSK-3β/Wnt/β-catenin signaling.
    Zhao G; Song Y; Dong L; Shi H; Li H; Yang L; Wang J
    Biochem Biophys Res Commun; 2019 Oct; 517(4):722-728. PubMed ID: 31395338
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Small Dibromotyrosine Derivative Purified From Pseudoceratina Sp. Suppresses TGF-β Responsiveness by Inhibiting TGF-β Type I Receptor Serine/Threonine Kinase Activity.
    Chen CL; Kao YC; Yang PH; Sung PJ; Wen ZH; Chen JJ; Huang YB; Chen PY
    J Cell Biochem; 2016 Dec; 117(12):2800-2814. PubMed ID: 27153151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential role of Sloan-Kettering Institute (Ski) protein in Nodal and transforming growth factor-beta (TGF-β)-induced Smad signaling in prostate cancer cells.
    Vo BT; Cody B; Cao Y; Khan SA
    Carcinogenesis; 2012 Nov; 33(11):2054-64. PubMed ID: 22843506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.
    Shinto O; Yashiro M; Kawajiri H; Shimizu K; Shimizu T; Miwa A; Hirakawa K
    Br J Cancer; 2010 Mar; 102(5):844-51. PubMed ID: 20145621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands.
    Batut J; Howell M; Hill CS
    Dev Cell; 2007 Feb; 12(2):261-74. PubMed ID: 17276343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability.
    Su CT; Huang JW; Chiang CK; Lawrence EC; Levine KL; Dabovic B; Jung C; Davis EC; Madan-Khetarpal S; Urban Z
    Hum Mol Genet; 2015 Jul; 24(14):4024-36. PubMed ID: 25882708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of lemur tyrosine kinase-2 protects neurons from oxygen-glucose deprivation/reoxygenation-induced injury through reinforcement of Nrf2 signaling by modulating GSK-3β phosphorylation.
    Bao H; Gao M
    Biochem Biophys Res Commun; 2020 Jan; 521(4):964-970. PubMed ID: 31722791
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells.
    Gonçalves V; Henriques AF; Pereira JF; Neves Costa A; Moyer MP; Moita LF; Gama-Carvalho M; Matos P; Jordan P
    RNA; 2014 Apr; 20(4):474-82. PubMed ID: 24550521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Downregulation of SMAD2, 4 and 6 mRNA and TGFbeta receptor I mRNA in lesional and non-lesional psoriatic skin.
    Yu H; Mrowietz U; Seifert O
    Acta Derm Venereol; 2009; 89(4):351-6. PubMed ID: 19688145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity.
    Manser C; Vagnoni A; Guillot F; Davies J; Miller CC
    J Neurochem; 2012 May; 121(3):343-8. PubMed ID: 22220831
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.