These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

72 related articles for article (PubMed ID: 21997370)

  • 1. Autophagy as a rescue mechanism in efavirenz-induced mitochondrial dysfunction: a lesson from hepatic cells.
    Apostolova N; Gomez-Sucerquia LJ; Gortat A; Blas-Garcia A; Esplugues JV
    Autophagy; 2011 Nov; 7(11):1402-4. PubMed ID: 21997370
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy.
    Apostolova N; Gomez-Sucerquia LJ; Gortat A; Blas-Garcia A; Esplugues JV
    Hepatology; 2011 Sep; 54(3):1009-19. PubMed ID: 21626526
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ER stress in human hepatic cells treated with Efavirenz: mitochondria again.
    Apostolova N; Gomez-Sucerquia LJ; Alegre F; Funes HA; Victor VM; Barrachina MD; Blas-Garcia A; Esplugues JV
    J Hepatol; 2013 Oct; 59(4):780-9. PubMed ID: 23792026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack.
    Martinez-Arroyo O; Gruevska A; Victor VM; González-Polo RA; Yakhine-Diop SMS; Fuentes JM; Esplugues JV; Blas-Garcia A; Apostolova N
    Antiviral Res; 2019 Aug; 168():36-50. PubMed ID: 31075350
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Depolarization of mitochondrial membrane potential is the initial event in non-nucleoside reverse transcriptase inhibitor efavirenz induced cytotoxicity.
    Ganta KK; Mandal A; Chaubey B
    Cell Biol Toxicol; 2017 Feb; 33(1):69-82. PubMed ID: 27639578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased MMAB level in mitochondria as a novel biomarker of hepatotoxicity induced by Efavirenz.
    Tan Z; Jia X; Ma F; Feng Y; Lu H; Jin JO; Wu D; Yin L; Liu L; Zhang L
    PLoS One; 2017; 12(11):e0188366. PubMed ID: 29190729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells.
    Blas-García A; Apostolova N; Ballesteros D; Monleón D; Morales JM; Rocha M; Victor VM; Esplugues JV
    Hepatology; 2010 Jul; 52(1):115-25. PubMed ID: 20564379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efavirenz induces neuronal autophagy and mitochondrial alterations.
    Purnell PR; Fox HS
    J Pharmacol Exp Ther; 2014 Nov; 351(2):250-8. PubMed ID: 25161171
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz.
    Gomez-Sucerquia LJ; Blas-Garcia A; Marti-Cabrera M; Esplugues JV; Apostolova N
    Antiviral Res; 2012 Jun; 94(3):232-41. PubMed ID: 22554935
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of mitochondrial toxicity of darunavir, raltegravir and rilpivirine in neurons and hepatocytes: a comparison with efavirenz.
    Blas-García A; Polo M; Alegre F; Funes HA; Martínez E; Apostolova N; Esplugues JV
    J Antimicrob Chemother; 2014 Nov; 69(11):2995-3000. PubMed ID: 25011651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuronal bioenergetics and acute mitochondrial dysfunction: a clue to understanding the central nervous system side effects of efavirenz.
    Funes HA; Apostolova N; Alegre F; Blas-Garcia A; Alvarez A; Marti-Cabrera M; Esplugues JV
    J Infect Dis; 2014 Nov; 210(9):1385-95. PubMed ID: 24813473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efavirenz Causes Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Endothelial Cells.
    Weiß M; Kost B; Renner-Müller I; Wolf E; Mylonas I; Brüning A
    Cardiovasc Toxicol; 2016 Jan; 16(1):90-9. PubMed ID: 25666561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial (dys)function - a factor underlying the variability of efavirenz-induced hepatotoxicity?
    Polo M; Alegre F; Funes HA; Blas-Garcia A; Victor VM; Esplugues JV; Apostolova N
    Br J Pharmacol; 2015 Apr; 172(7):1713-27. PubMed ID: 25411110
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells.
    Apostolova N; Gomez-Sucerquia LJ; Moran A; Alvarez A; Blas-Garcia A; Esplugues JV
    Br J Pharmacol; 2010 Aug; 160(8):2069-84. PubMed ID: 20649602
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation.
    Stankov MV; Panayotova-Dimitrova D; Leverkus M; Vondran FW; Bauerfeind R; Binz A; Behrens GM
    AIDS; 2012 Oct; 26(16):1995-2006. PubMed ID: 22914580
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug-induced toxicity in vitro.
    Alegre F; Moragrega ÁB; Polo M; Marti-Rodrigo A; Esplugues JV; Blas-Garcia A; Apostolova N
    Br J Pharmacol; 2018 Feb; 175(3):440-455. PubMed ID: 29148034
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efavirenz induces autophagy and aberrant differentiation in normal human keratinocytes.
    Dong Q; Oh JE; Yi JK; Kim RH; Shin KH; Mitsuyasu R; Park NH; Kang MK
    Int J Mol Med; 2013 Jun; 31(6):1305-12. PubMed ID: 23563240
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efavirenz-induced neurological symptoms in rare homozygote CYP2B6 *2/*2 (C64T).
    Usami O; Ashino Y; Komaki Y; Tomaki M; Irokawa T; Tamada T; Hayashida T; Teruya K; Hattori T
    Int J STD AIDS; 2007 Aug; 18(8):575-6. PubMed ID: 17686225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phase IV, double-blind, multicentre, randomized, placebo-controlled, pilot study to assess the feasibility of switching individuals receiving efavirenz with continuing central nervous system adverse events to etravirine.
    Waters L; Fisher M; Winston A; Higgs C; Hadley W; Garvey L; Mandalia S; Perry N; Nicola M; Nelson M
    AIDS; 2011 Jan; 25(1):65-71. PubMed ID: 21099666
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lopinavir/ritonavir or efavirenz plus two nucleoside analogues as first-line antiretroviral therapy: a non-randomized comparison.
    De Luca A; Cozzi-Lepri A; Antinori A; Zaccarelli M; Bongiovanni M; Di Giambenedetto S; Marconi P; Cicconi P; Resta F; Grisorio B; Ciardi M; Cauda R; Monforte Ad; ; ; ;
    Antivir Ther; 2006; 11(5):609-18. PubMed ID: 16964829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.