253 related articles for article (PubMed ID: 21998636)
1. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity.
Sharlow ER; Mustata Wilson G; Close D; Leimgruber S; Tandon M; Reed RB; Shun TY; Wang QJ; Wipf P; Lazo JS
PLoS One; 2011; 6(10):e25134. PubMed ID: 21998636
[TBL] [Abstract][Full Text] [Related]
2. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.
Sharlow ER; Giridhar KV; LaValle CR; Chen J; Leimgruber S; Barrett R; Bravo-Altamirano K; Wipf P; Lazo JS; Wang QJ
J Biol Chem; 2008 Nov; 283(48):33516-26. PubMed ID: 18829454
[TBL] [Abstract][Full Text] [Related]
3. A targeted library screen reveals a new inhibitor scaffold for protein kinase D.
Tandon M; Wang L; Xu Q; Xie X; Wipf P; Wang QJ
PLoS One; 2012; 7(9):e44653. PubMed ID: 23028574
[TBL] [Abstract][Full Text] [Related]
4. Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site.
Rippin I; Khazanov N; Shirley Ben Joseph ; Kudinov T; Berent E; Arciniegas Ruiz SM; Marciano D; Levy L; Gruzman A; Senderowitz H; Eldar-Finkelman H
Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33218072
[TBL] [Abstract][Full Text] [Related]
5. The design, annotation, and application of a kinase-targeted library.
Xi H; Lunney EA
Methods Mol Biol; 2011; 685():279-91. PubMed ID: 20981529
[TBL] [Abstract][Full Text] [Related]
6. Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916.
Rybin VO; Guo J; Steinberg SF
J Biol Chem; 2009 Jan; 284(4):2332-43. PubMed ID: 19029298
[TBL] [Abstract][Full Text] [Related]
7. Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.
Simard JR; Getlik M; Grütter C; Pawar V; Wulfert S; Rabiller M; Rauh D
J Am Chem Soc; 2009 Sep; 131(37):13286-96. PubMed ID: 19572644
[TBL] [Abstract][Full Text] [Related]
8. The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor.
Capurro V; Lanfranco M; Summa M; Porceddu PF; Ciampoli M; Margaroli N; Durando L; Garrone B; Ombrato R; Tongiani S; Reggiani A
Biomed Pharmacother; 2020 Aug; 128():110249. PubMed ID: 32470749
[TBL] [Abstract][Full Text] [Related]
9. Computational design of new protein kinase D 1 (PKD1) inhibitors: homology-based active site prediction, energy-optimized pharmacophore, docking and database screening.
Nalini ; Chadha N; Bahia MS; Kaur M; Bahadur R; Silakari O
Mol Divers; 2018 Feb; 22(1):47-56. PubMed ID: 29058231
[TBL] [Abstract][Full Text] [Related]
10. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family.
Chen J; Deng F; Li J; Wang QJ
Biochem J; 2008 Apr; 411(2):333-42. PubMed ID: 18076381
[TBL] [Abstract][Full Text] [Related]
11. Developments in selective small molecule ATP-targeting the serine/threonine kinase Akt/PKB.
Wang P; Zhang L; Hao Q; Zhao G
Mini Rev Med Chem; 2011 Nov; 11(13):1093-107. PubMed ID: 22353219
[TBL] [Abstract][Full Text] [Related]
12. Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor.
Wilson BA; Alam MS; Guszczynski T; Jakob M; Shenoy SR; Mitchell CA; Goncharova EI; Evans JR; Wipf P; Liu G; Ashwell JD; O'Keefe BR
J Biomol Screen; 2016 Mar; 21(3):277-89. PubMed ID: 26538432
[TBL] [Abstract][Full Text] [Related]
13. Discovery of inter-domain stabilizers-a novel assay system for allosteric akt inhibitors.
Fang Z; Simard JR; Plenker D; Nguyen HD; Phan T; Wolle P; Baumeister S; Rauh D
ACS Chem Biol; 2015 Jan; 10(1):279-88. PubMed ID: 24959717
[TBL] [Abstract][Full Text] [Related]
14. A historical overview of protein kinases and their targeted small molecule inhibitors.
Roskoski R
Pharmacol Res; 2015 Oct; 100():1-23. PubMed ID: 26207888
[TBL] [Abstract][Full Text] [Related]
15. A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities.
Chen J; Giridhar KV; Zhang L; Xu S; Wang QJ
Carcinogenesis; 2011 Aug; 32(8):1198-206. PubMed ID: 21665893
[TBL] [Abstract][Full Text] [Related]
16. Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase.
van Linden OP; Farenc C; Zoutman WH; Hameetman L; Wijtmans M; Leurs R; Tensen CP; Siegal G; de Esch IJ
Eur J Med Chem; 2012 Jan; 47(1):493-500. PubMed ID: 22137457
[TBL] [Abstract][Full Text] [Related]
17. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells.
Tandon M; Johnson J; Li Z; Xu S; Wipf P; Wang QJ
PLoS One; 2013; 8(9):e75601. PubMed ID: 24086585
[TBL] [Abstract][Full Text] [Related]
18. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.
Park H; Chi O; Kim J; Hong S
J Chem Inf Model; 2011 Nov; 51(11):2986-93. PubMed ID: 22017333
[TBL] [Abstract][Full Text] [Related]
19. Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase 1.
Yun T; Qin T; Liu Y; Lai L
ChemMedChem; 2016 Apr; 11(7):713-7. PubMed ID: 27061239
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel pyruvate dehydrogenase kinases inhibitors by screening of an in-house small molecule library for anti-lung cancer therapeutics.
Guo F; Zhao S; Li X
Bioorg Med Chem Lett; 2019 Jan; 29(2):291-296. PubMed ID: 30470491
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
