BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 22002845)

  • 1. Population pharmacokinetic-pharmacodynamic-disease progression model for effects of anakinra in Lewis rats with collagen-induced arthritis.
    Liu D; Lon HK; Dubois DC; Almon RR; Jusko WJ
    J Pharmacokinet Pharmacodyn; 2011 Dec; 38(6):769-86. PubMed ID: 22002845
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach.
    Lon HK; Liu D; DuBois DC; Almon RR; Jusko WJ
    J Pharmacokinet Pharmacodyn; 2013 Dec; 40(6):701-12. PubMed ID: 24233383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetic-pharmacodynamic disease progression model for effect of etanercept in Lewis rats with collagen-induced arthritis.
    Lon HK; Liu D; Zhang Q; DuBois DC; Almon RR; Jusko WJ
    Pharm Res; 2011 Jul; 28(7):1622-30. PubMed ID: 21360252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacokinetics, pharmacodynamics and toxicities of methotrexate in healthy and collagen-induced arthritic rats.
    Liu DY; Lon HK; Wang YL; DuBois DC; Almon RR; Jusko WJ
    Biopharm Drug Dispos; 2013 May; 34(4):203-14. PubMed ID: 23456770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies.
    Stolina M; Schett G; Dwyer D; Vonderfecht S; Middleton S; Duryea D; Pacheco E; Van G; Bolon B; Feige U; Zack D; Kostenuik P
    Arthritis Res Ther; 2009; 11(6):R187. PubMed ID: 20003323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats.
    Song D; DuBois DC; Almon RR; Jusko WJ
    Pharm Res; 2018 Sep; 35(11):203. PubMed ID: 30191329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis.
    Zuurmond AM; Koudijs A; van El B; Doornbos RP; van Manen-Vernooij BC; Bastiaans JH; Penninks AH; van Bilsen JH; Cnubben NH; Degroot J
    Regul Toxicol Pharmacol; 2011 Apr; 59(3):461-70. PubMed ID: 21300126
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis.
    Li X; DuBois DC; Almon RR; Jusko WJ
    Drug Metab Dispos; 2017 May; 45(5):484-491. PubMed ID: 28246127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modeling and design of challenge tests: Inflammatory and metabolic biomarker study examples.
    Gabrielsson J; Hjorth S; Vogg B; Harlfinger S; Gutierrez PM; Peletier L; Pehrson R; Davidsson P
    Eur J Pharm Sci; 2015 Jan; 67():144-159. PubMed ID: 25435491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.
    Earp JC; Dubois DC; Molano DS; Pyszczynski NA; Almon RR; Jusko WJ
    J Pharmacol Exp Ther; 2008 Aug; 326(2):546-54. PubMed ID: 18448864
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data.
    Bendele A; McAbee T; Sennello G; Frazier J; Chlipala E; McCabe D
    Arthritis Rheum; 1999 Mar; 42(3):498-506. PubMed ID: 10088773
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats.
    Li X; DuBois DC; Almon RR; Jusko WJ
    Drug Metab Dispos; 2017 May; 45(5):476-483. PubMed ID: 28246126
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exposure-Effect Relationships in Established Rat Adjuvant-Induced and Collagen-Induced Arthritis: A Translational Pharmacokinetic-Pharmacodynamic Analysis.
    Wong H; Liu L; Ouyang W; Deng Y; Wright MR; Hop CECA
    J Pharmacol Exp Ther; 2019 Jun; 369(3):406-418. PubMed ID: 30940693
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.
    Earp JC; Dubois DC; Molano DS; Pyszczynski NA; Keller CE; Almon RR; Jusko WJ
    J Pharmacol Exp Ther; 2008 Aug; 326(2):532-45. PubMed ID: 18448865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of interleukin-1β in arthritic pain: main involvement in thermal, but not mechanical, hyperalgesia in rat antigen-induced arthritis.
    Ebbinghaus M; Uhlig B; Richter F; von Banchet GS; Gajda M; Bräuer R; Schaible HG
    Arthritis Rheum; 2012 Dec; 64(12):3897-907. PubMed ID: 22933159
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiarthritis effect of a novel Bruton's tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy.
    Liu L; Di Paolo J; Barbosa J; Rong H; Reif K; Wong H
    J Pharmacol Exp Ther; 2011 Jul; 338(1):154-63. PubMed ID: 21521773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative dynamic models of arthritis progression in the rat.
    Earp JC; Dubois DC; Almon RR; Jusko WJ
    Pharm Res; 2009 Jan; 26(1):196-203. PubMed ID: 18758921
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inflammatory cytokine levels in paw tissues during development of rat collagen-induced arthritis: effect of FK506, an inhibitor of T cell activation.
    Magari K; Miyata S; Ohkubo Y; Mutoh S
    Inflamm Res; 2004 Sep; 53(9):469-74. PubMed ID: 15551000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats.
    Gao Q; Qin H; Zhu L; Li D; Hao X
    Int Immunopharmacol; 2020 Jul; 84():106527. PubMed ID: 32402948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
    Yu H; Zeng R; Lin Y; Li X; Tasneem S; Yang Z; Qiu YX; Li B; Wang YH; Cai X; Wang W
    Phytomedicine; 2019 May; 58():152876. PubMed ID: 30851579
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.