BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 22002996)

  • 1. An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis.
    Jun AS; Meng H; Ramanan N; Matthaei M; Chakravarti S; Bonshek R; Black GC; Grebe R; Kimos M
    Hum Mol Genet; 2012 Jan; 21(2):384-93. PubMed ID: 22002996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy.
    Meng H; Matthaei M; Ramanan N; Grebe R; Chakravarti S; Speck CL; Kimos M; Vij N; Eberhart CG; Jun AS
    Invest Ophthalmol Vis Sci; 2013 Mar; 54(3):1887-97. PubMed ID: 23422828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biomechanical changes to Descemet's membrane precede endothelial cell loss in an early-onset murine model of Fuchs endothelial corneal dystrophy.
    Leonard BC; Jalilian I; Raghunathan VK; Wang W; Jun AS; Murphy CJ; Thomasy SM
    Exp Eye Res; 2019 Mar; 180():18-22. PubMed ID: 30471280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endothelial Cdkn1a (p21) overexpression and accelerated senescence in a mouse model of Fuchs endothelial corneal dystrophy.
    Matthaei M; Meng H; Meeker AK; Eberhart CG; Jun AS
    Invest Ophthalmol Vis Sci; 2012 Sep; 53(10):6718-27. PubMed ID: 22956607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endothelial cell whole genome expression analysis in a mouse model of early-onset Fuchs' endothelial corneal dystrophy.
    Matthaei M; Hu J; Meng H; Lackner EM; Eberhart CG; Qian J; Hao H; Jun AS
    Invest Ophthalmol Vis Sci; 2013 Mar; 54(3):1931-40. PubMed ID: 23449721
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lithium treatment increases endothelial cell survival and autophagy in a mouse model of Fuchs endothelial corneal dystrophy.
    Kim EC; Meng H; Jun AS
    Br J Ophthalmol; 2013 Aug; 97(8):1068-73. PubMed ID: 23759441
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Missense mutations in COL8A2, the gene encoding the alpha2 chain of type VIII collagen, cause two forms of corneal endothelial dystrophy.
    Biswas S; Munier FL; Yardley J; Hart-Holden N; Perveen R; Cousin P; Sutphin JE; Noble B; Batterbury M; Kielty C; Hackett A; Bonshek R; Ridgway A; McLeod D; Sheffield VC; Stone EM; Schorderet DF; Black GC
    Hum Mol Genet; 2001 Oct; 10(21):2415-23. PubMed ID: 11689488
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunohistochemistry and electron microscopy of early-onset fuchs corneal dystrophy in three cases with the same L450W COL8A2 mutation.
    Zhang C; Bell WR; Sundin OH; De La Cruz Z; Stark WJ; Green WR; Gottsch JD
    Trans Am Ophthalmol Soc; 2006; 104():85-97. PubMed ID: 17471329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A cellular model for the investigation of Fuchs' endothelial corneal dystrophy.
    Kelliher C; Chakravarti S; Vij N; Mazur S; Stahl PJ; Engler C; Matthaei M; Yu SM; Jun AS
    Exp Eye Res; 2011 Dec; 93(6):880-8. PubMed ID: 22020132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-Acetylcysteine increases corneal endothelial cell survival in a mouse model of Fuchs endothelial corneal dystrophy.
    Kim EC; Meng H; Jun AS
    Exp Eye Res; 2014 Oct; 127():20-5. PubMed ID: 24952277
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy.
    Okumura N; Kitahara M; Okuda H; Hashimoto K; Ueda E; Nakahara M; Kinoshita S; Young RD; Quantock AJ; Tourtas T; Schlötzer-Schrehardt U; Kruse F; Koizumi N
    Invest Ophthalmol Vis Sci; 2017 Jul; 58(9):3697-3707. PubMed ID: 28727885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Q455V mutation in COL8A2 is associated with Fuchs' corneal dystrophy in Korean patients.
    Mok JW; Kim HS; Joo CK
    Eye (Lond); 2009 Apr; 23(4):895-903. PubMed ID: 18464802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. No pathogenic mutations identified in the COL8A1 and COL8A2 genes in familial Fuchs corneal dystrophy.
    Aldave AJ; Rayner SA; Salem AK; Yoo GL; Kim BT; Saeedian M; Sonmez B; Yellore VS
    Invest Ophthalmol Vis Sci; 2006 Sep; 47(9):3787-90. PubMed ID: 16936088
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of ion transporters and increased unfolded protein response in Fuchs' dystrophy.
    Jalimarada SS; Ogando DG; Bonanno JA
    Mol Vis; 2014; 20():1668-79. PubMed ID: 25548511
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fuchs corneal dystrophy: aberrant collagen distribution in an L450W mutant of the COL8A2 gene.
    Gottsch JD; Zhang C; Sundin OH; Bell WR; Stark WJ; Green WR
    Invest Ophthalmol Vis Sci; 2005 Dec; 46(12):4504-11. PubMed ID: 16303941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endothelial cell microRNA expression in human late-onset Fuchs' dystrophy.
    Matthaei M; Hu J; Kallay L; Eberhart CG; Cursiefen C; Qian J; Lackner EM; Jun AS
    Invest Ophthalmol Vis Sci; 2014 Jan; 55(1):216-25. PubMed ID: 24334445
    [TBL] [Abstract][Full Text] [Related]  

  • 17.
    Moschos MM; Diamantopoulou A; Gouliopoulos N; Droutsas K; Bagli E; Chatzistefanou K; Kitsos G; Kroupis C
    In Vivo; 2019; 33(3):963-971. PubMed ID: 31028223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy.
    Igo RP; Kopplin LJ; Joseph P; Truitt B; Fondran J; Bardenstein D; Aldave AJ; Croasdale CR; Price MO; Rosenwasser M; Lass JH; Iyengar SK;
    PLoS One; 2012; 7(10):e46742. PubMed ID: 23110055
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extracellular Matrix and Integrin Expression Profiles in Fuchs Endothelial Corneal Dystrophy Cells and Tissue Model.
    Goyer B; Thériault M; Gendron SP; Brunette I; Rochette PJ; Proulx S
    Tissue Eng Part A; 2018 Apr; 24(7-8):607-615. PubMed ID: 28726551
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biosynthetic and functional defects in newly identified SLC4A11 mutants and absence of COL8A2 mutations in Fuchs endothelial corneal dystrophy.
    Soumittra N; Loganathan SK; Madhavan D; Ramprasad VL; Arokiasamy T; Sumathi S; Karthiyayini T; Rachapalli SR; Kumaramanickavel G; Casey JR; Rajagopal R
    J Hum Genet; 2014 Aug; 59(8):444-53. PubMed ID: 25007886
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.