These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 22006203)

  • 1. Kinetics and mechanisms of deamidation and covalent amide-linked adduct formation in amorphous lyophiles of a model asparagine-containing Peptide.
    Dehart MP; Anderson BD
    Pharm Res; 2012 Oct; 29(10):2722-37. PubMed ID: 22006203
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of water and polymer content on covalent amide-linked adduct formation in peptide-containing amorphous lyophiles.
    DeHart MP; Anderson BD
    J Pharm Sci; 2012 Sep; 101(9):3142-56. PubMed ID: 22437444
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A mechanism-based kinetic analysis of succinimide-mediated deamidation, racemization, and covalent adduct formation in a model peptide in amorphous lyophiles.
    Dehart MP; Anderson BD
    J Pharm Sci; 2012 Sep; 101(9):3096-109. PubMed ID: 22271437
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of the cyclic imide in alternate degradation pathways for asparagine-containing peptides and proteins.
    Dehart MP; Anderson BD
    J Pharm Sci; 2007 Oct; 96(10):2667-85. PubMed ID: 17518358
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
    Geiger T; Clarke S
    J Biol Chem; 1987 Jan; 262(2):785-94. PubMed ID: 3805008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deamidation via cyclic imide in asparaginyl peptides.
    Capasso S; Mazzarella L; Sica F; Zagari A
    Pept Res; 1989; 2(2):195-200. PubMed ID: 2520758
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deamidation of asparagine residues: direct hydrolysis versus succinimide-mediated deamidation mechanisms.
    Catak S; Monard G; Aviyente V; Ruiz-López MF
    J Phys Chem A; 2009 Feb; 113(6):1111-20. PubMed ID: 19152321
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of a histidine residue on the C-terminal side of an asparaginyl residue on the rate of deamidation using model pentapeptides.
    Goolcharran C; Stauffer LL; Cleland JL; Borchardt RT
    J Pharm Sci; 2000 Jun; 89(6):818-25. PubMed ID: 10824141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solid-state stability of human insulin. I. Mechanism and the effect of water on the kinetics of degradation in lyophiles from pH 2-5 solutions.
    Strickley RG; Anderson BD
    Pharm Res; 1996 Aug; 13(8):1142-53. PubMed ID: 8865303
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of 'pH' on the rate of asparagine deamidation in polymeric formulations: 'pH'-rate profile.
    Song Y; Schowen RL; Borchardt RT; Topp EM
    J Pharm Sci; 2001 Feb; 90(2):141-56. PubMed ID: 11169531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state.
    Li B; Gorman EM; Moore KD; Williams T; Schowen RL; Topp EM; Borchardt RT
    J Pharm Sci; 2005 Mar; 94(3):666-75. PubMed ID: 15668945
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neighboring side chain effects on asparaginyl and aspartyl degradation: an ab initio study of the relationship between peptide conformation and backbone NH acidity.
    Radkiewicz JL; Zipse H; Clarke S; Houk KN
    J Am Chem Soc; 2001 Apr; 123(15):3499-506. PubMed ID: 11472122
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical pathways of peptide degradation. II. Kinetics of deamidation of an asparaginyl residue in a model hexapeptide.
    Patel K; Borchardt RT
    Pharm Res; 1990 Jul; 7(7):703-11. PubMed ID: 2395797
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetics and mechanism for the reaction of cysteine with hydrogen peroxide in amorphous polyvinylpyrrolidone lyophiles.
    Luo D; Anderson BD
    Pharm Res; 2006 Oct; 23(10):2239-53. PubMed ID: 16951993
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of a Hydroxyl Group on the Deamidation and Dehydration Reactions of Protonated Asparagine-Serine Investigated by Combined Spectroscopic, Guided Ion Beam, and Theoretical Approaches.
    Boles GC; Kempkes LJM; Martens J; Berden G; Oomens J; Armentrout PB
    J Am Soc Mass Spectrom; 2021 Mar; 32(3):786-805. PubMed ID: 33570934
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Computational Study of the Mechanism of Succinimide Formation in the Asn-His Sequence: Intramolecular Catalysis by the His Side Chain.
    Takahashi O; Manabe N; Kirikoshi R
    Molecules; 2016 Mar; 21(3):327. PubMed ID: 27005609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deamidation and succinimide formation by gamma-N-methylasparagine: potential pitfalls of amino acid analysis.
    Klotz AV; Higgins BM
    Arch Biochem Biophys; 1991 Nov; 291(1):113-20. PubMed ID: 1929425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping.
    Zhang YT; Hu J; Pace AL; Wong R; Wang YJ; Kao YH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Aug; 965():65-71. PubMed ID: 24999246
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of the three-dimensional structure on the deamidation reaction of ribonuclease A.
    Capasso S; Salvadori S
    J Pept Res; 1999 Nov; 54(5):377-82. PubMed ID: 10563503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Racemization of an asparagine residue during peptide deamidation.
    Li B; Borchardt RT; Topp EM; VanderVelde D; Schowen RL
    J Am Chem Soc; 2003 Sep; 125(38):11486-7. PubMed ID: 13129337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.