BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 22008152)

  • 1. Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells.
    Burleigh SC; van de Laar T; Stroop CJ; van Grunsven WM; O'Donoghue N; Rudd PM; Davey GP
    BMC Biotechnol; 2011 Oct; 11():95. PubMed ID: 22008152
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A study on enhanced O-glycosylation strategy for improved production of recombinant human chorionic gonadotropin in Chinese hamster ovary cells.
    Deng Z; Yi X; Chu J; Zhuang Y
    J Biotechnol; 2019 Dec; 306():159-168. PubMed ID: 31604106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical inhibitors of hexokinase-2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce altered glycoforms in CHO cell cultures.
    Naik HM; Kumar S; Reddy JV; Gonzalez JE; McConnell BO; Dhara VG; Wang T; Yu M; Antoniewicz MR; Betenbaugh MJ
    Biotechnol Bioeng; 2023 Sep; 120(9):2559-2577. PubMed ID: 37148536
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic effects on recombinant interferon-gamma glycosylation in continuous culture of Chinese hamster ovary cells.
    Nyberg GB; Balcarcel RR; Follstad BD; Stephanopoulos G; Wang DI
    Biotechnol Bioeng; 1999 Feb; 62(3):336-47. PubMed ID: 10099545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic control of recombinant protein N-glycan processing in NS0 and CHO cells.
    Baker KN; Rendall MH; Hills AE; Hoare M; Freedman RB; James DC
    Biotechnol Bioeng; 2001 May; 73(3):188-202. PubMed ID: 11257601
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of ammonia and glucosamine on the heterogeneity of erythropoietin glycoforms.
    Yang M; Butler M
    Biotechnol Prog; 2002; 18(1):129-38. PubMed ID: 11822911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.
    Fan Y; Jimenez Del Val I; Müller C; Wagtberg Sen J; Rasmussen SK; Kontoravdi C; Weilguny D; Andersen MR
    Biotechnol Bioeng; 2015 Mar; 112(3):521-35. PubMed ID: 25220616
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of dynamic online fed-batch strategies on metabolism, productivity and N-glycosylation quality in CHO cell cultures.
    Chee Furng Wong D; Tin Kam Wong K; Tang Goh L; Kiat Heng C; Gek Sim Yap M
    Biotechnol Bioeng; 2005 Jan; 89(2):164-77. PubMed ID: 15593097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of nutrient levels and average culture pH on the glycosylation pattern of camelid-humanized monoclonal antibody.
    Aghamohseni H; Ohadi K; Spearman M; Krahn N; Moo-Young M; Scharer JM; Butler M; Budman HM
    J Biotechnol; 2014 Sep; 186():98-109. PubMed ID: 25014402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms.
    Gawlitzek M; Ryll T; Lofgren J; Sliwkowski MB
    Biotechnol Bioeng; 2000 Jun; 68(6):637-46. PubMed ID: 10799988
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An investigation of intracellular glycosylation activities in CHO cells: effects of nucleotide sugar precursor feeding.
    Wong NS; Wati L; Nissom PM; Feng HT; Lee MM; Yap MG
    Biotechnol Bioeng; 2010 Oct; 107(2):321-36. PubMed ID: 20506284
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells.
    Goldman MH; James DC; Rendall M; Ison AP; Hoare M; Bull AT
    Biotechnol Bioeng; 1998 Dec; 60(5):596-607. PubMed ID: 10099468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma glycosylation during batch and fed-batch cultures of CHO cells.
    Kochanowski N; Blanchard F; Cacan R; Chirat F; Guedon E; Marc A; Goergen JL
    Biotechnol Bioeng; 2008 Jul; 100(4):721-33. PubMed ID: 18496872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How does mild hypothermia affect monoclonal antibody glycosylation?
    Sou SN; Sellick C; Lee K; Mason A; Kyriakopoulos S; Polizzi KM; Kontoravdi C
    Biotechnol Bioeng; 2015 Jun; 112(6):1165-76. PubMed ID: 25545631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
    Hills AE; Patel A; Boyd P; James DC
    Biotechnol Bioeng; 2001 Oct; 75(2):239-51. PubMed ID: 11536148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation.
    Yin B; Gao Y; Chung CY; Yang S; Blake E; Stuczynski MC; Tang J; Kildegaard HF; Andersen MR; Zhang H; Betenbaugh MJ
    Biotechnol Bioeng; 2015 Nov; 112(11):2343-51. PubMed ID: 26154505
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture.
    Fan Y; Jimenez Del Val I; Müller C; Lund AM; Sen JW; Rasmussen SK; Kontoravdi C; Baycin-Hizal D; Betenbaugh MJ; Weilguny D; Andersen MR
    Biotechnol Bioeng; 2015 Oct; 112(10):2172-84. PubMed ID: 25899530
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy.
    Goudar C; Biener R; Boisart C; Heidemann R; Piret J; de Graaf A; Konstantinov K
    Metab Eng; 2010 Mar; 12(2):138-49. PubMed ID: 19896555
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineer Medium and Feed for Modulating N-Glycosylation of Recombinant Protein Production in CHO Cell Culture.
    Fan Y; Kildegaard HF; Andersen MR
    Methods Mol Biol; 2017; 1603():209-226. PubMed ID: 28493133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combining mechanistic and data-driven approaches to gain process knowledge on the control of the metabolic shift to lactate uptake in a fed-batch CHO process.
    Zalai D; Koczka K; Párta L; Wechselberger P; Klein T; Herwig C
    Biotechnol Prog; 2015; 31(6):1657-68. PubMed ID: 26439213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.