162 related articles for article (PubMed ID: 22008537)
1. Expression of albumin and cytochrome P450 enzymes in HepG2 cells cultured with a nanotechnology-based culture plate with microfabricated scaffold.
Nakamura K; Kato N; Aizawa K; Mizutani R; Yamauchi J; Tanoue A
J Toxicol Sci; 2011 Oct; 36(5):625-33. PubMed ID: 22008537
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system.
Nakamura K; Mizutani R; Sanbe A; Enosawa S; Kasahara M; Nakagawa A; Ejiri Y; Murayama N; Miyamoto Y; Torii T; Kusakawa S; Yamauchi J; Fukuda M; Yamazaki H; Tanoue A
J Biosci Bioeng; 2011 Jan; 111(1):78-84. PubMed ID: 20837398
[TBL] [Abstract][Full Text] [Related]
3. 3D spheroid cultures improve the metabolic gene expression profiles of HepaRG cells.
Takahashi Y; Hori Y; Yamamoto T; Urashima T; Ohara Y; Tanaka H
Biosci Rep; 2015 May; 35(3):. PubMed ID: 26182370
[TBL] [Abstract][Full Text] [Related]
4. A three-dimensional collagen-sponge-based culture system coated with simplified recombinant fibronectin improves the function of a hepatocyte cell line.
Nishida Y; Taniguchi A
In Vitro Cell Dev Biol Anim; 2016 Mar; 52(3):271-277. PubMed ID: 26714750
[TBL] [Abstract][Full Text] [Related]
5. Secretion of albumin and induction of CYP1A2 and CYP3A4 in novel three-dimensional culture system for human hepatocytes using micro-space plate.
Nishimura M; Hagi M; Ejiri Y; Kishimoto S; Horie T; Narimatsu S; Naito S
Drug Metab Pharmacokinet; 2010; 25(3):236-42. PubMed ID: 20610882
[TBL] [Abstract][Full Text] [Related]
6. CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.
Benet M; Lahoz A; Guzmán C; Castell JV; Jover R
J Biol Chem; 2010 Sep; 285(37):28457-71. PubMed ID: 20622021
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of three-dimensional cultured HepG2 cells in a nano culture plate system: an in vitro human model of acetaminophen hepatotoxicity.
Aritomi K; Ishitsuka Y; Tomishima Y; Shimizu D; Abe N; Shuto T; Irikura M; Kai H; Irie T
J Pharmacol Sci; 2014; 124(2):218-29. PubMed ID: 24492462
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of the metabolic capability of primary human hepatocytes in three-dimensional cultures on microstructural plates.
Koyama S; Arakawa H; Itoh M; Masuda N; Yano K; Kojima H; Ogihara T
Biopharm Drug Dispos; 2018 Apr; 39(4):187-195. PubMed ID: 29469947
[TBL] [Abstract][Full Text] [Related]
9. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
Schulz C; Kammerer S; Küpper JH
Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
[TBL] [Abstract][Full Text] [Related]
10. Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells.
Novotna A; Doricakova A; Vrzal R; Pavek P; Dvorak Z
Eur J Pharmacol; 2011 Nov; 669(1-3):45-50. PubMed ID: 21871880
[TBL] [Abstract][Full Text] [Related]
11. Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity.
Ruoß M; Damm G; Vosough M; Ehret L; Grom-Baumgarten C; Petkov M; Naddalin S; Ladurner R; Seehofer D; Nussler A; Sajadian S
Int J Mol Sci; 2019 Jan; 20(2):. PubMed ID: 30654452
[TBL] [Abstract][Full Text] [Related]
12. CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.
Wattanavanitchakorn S; Rojvirat P; Chavalit T; MacDonald MJ; Jitrapakdee S
PLoS One; 2018; 13(3):e0194252. PubMed ID: 29566023
[TBL] [Abstract][Full Text] [Related]
13. Human hepatocarcinoma functional liver cell-4 cell line exhibits high expression of drug-metabolizing enzymes in three-dimensional culture.
Kato R; Shigemoto K; Akiyama H; Ieda A; Ijiri Y; Hayashi T
Biol Pharm Bull; 2014; 37(11):1782-7. PubMed ID: 25366484
[TBL] [Abstract][Full Text] [Related]
14. Comparative analysis of 3D culture methods on human HepG2 cells.
Luckert C; Schulz C; Lehmann N; Thomas M; Hofmann U; Hammad S; Hengstler JG; Braeuning A; Lampen A; Hessel S
Arch Toxicol; 2017 Jan; 91(1):393-406. PubMed ID: 26872951
[TBL] [Abstract][Full Text] [Related]
15. Characteristics of three-dimensional prospectively isolated mouse bone marrow mesenchymal stem/stromal cell aggregates on nanoculture plates.
Obara C; Tomiyama K; Takizawa K; Islam R; Yasuda T; Gotoh T; Tajima K
Cell Tissue Res; 2016 Oct; 366(1):113-27. PubMed ID: 27100525
[TBL] [Abstract][Full Text] [Related]
16. A microfabricated scaffold induces the spheroid formation of human bone marrow-derived mesenchymal progenitor cells and promotes efficient adipogenic differentiation.
Miyagawa Y; Okita H; Hiroyama M; Sakamoto R; Kobayashi M; Nakajima H; Katagiri YU; Fujimoto J; Hata J; Umezawa A; Kiyokawa N
Tissue Eng Part A; 2011 Feb; 17(3-4):513-21. PubMed ID: 20818998
[TBL] [Abstract][Full Text] [Related]
17. A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies.
Ramaiahgari SC; den Braver MW; Herpers B; Terpstra V; Commandeur JN; van de Water B; Price LS
Arch Toxicol; 2014 May; 88(5):1083-95. PubMed ID: 24599296
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes.
Koeda A; Iwao T; Nakanishi A; Mizuno S; Yamashita M; Sakai Y; Nakamura K; Matsunaga T
Drug Metab Pharmacokinet; 2020 Jun; 35(3):304-312. PubMed ID: 32303457
[TBL] [Abstract][Full Text] [Related]
19. HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.
Choi JM; Oh SJ; Lee SY; Im JH; Oh JM; Ryu CS; Kwak HC; Lee JY; Kang KW; Kim SK
Arch Pharm Res; 2015; 38(5):691-704. PubMed ID: 25336106
[TBL] [Abstract][Full Text] [Related]
20. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening.
Wang Z; Luo X; Anene-Nzelu C; Yu Y; Hong X; Singh NH; Xia L; Liu S; Yu H
J Appl Toxicol; 2015 Aug; 35(8):909-17. PubMed ID: 25512232
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
