271 related articles for article (PubMed ID: 22009189)
1. Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia.
Dorababu P; Nagesh N; Linga VG; Gundeti S; Kutala VK; Reddanna P; Digumarti R
Eur J Clin Pharmacol; 2012 Apr; 68(4):379-87. PubMed ID: 22009189
[TBL] [Abstract][Full Text] [Related]
2. Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia.
Naushad SM; Dorababu P; Rupasree Y; Pavani A; Raghunadharao D; Hussain T; Alrokayan SA; Kutala VK
Cancer Chemother Pharmacol; 2019 May; 83(5):875-880. PubMed ID: 30806759
[TBL] [Abstract][Full Text] [Related]
3. The Role of TPMT, ITPA, and NUDT15 Variants during Mercaptopurine Treatment of Swedish Pediatric Patients with Acute Lymphoblastic Leukemia.
Wahlund M; Nilsson A; Kahlin AZ; Broliden K; Myrberg IH; Appell ML; Berggren A
J Pediatr; 2020 Jan; 216():150-157.e1. PubMed ID: 31635813
[TBL] [Abstract][Full Text] [Related]
4. Dosage of 6-Mercaptopurine in Relation to Genetic TPMT and ITPA Variants: Toward Individualized Pediatric Acute Lymphoblastic Leukemia Maintenance Treatment.
Kouwenberg TW; van den Bosch BJC; Bierau J; Te Loo DMWM; Coenen MJH; Hagleitner MM
J Pediatr Hematol Oncol; 2020 Mar; 42(2):e94-e97. PubMed ID: 31895215
[TBL] [Abstract][Full Text] [Related]
5. Prevalence of TPMT and ITPA gene polymorphisms and effect on mercaptopurine dosage in Chilean children with acute lymphoblastic leukemia.
Farfan MJ; Salas C; Canales C; Silva F; Villarroel M; Kopp K; Torres JP; Santolaya ME; Morales J
BMC Cancer; 2014 Apr; 14():299. PubMed ID: 24774509
[TBL] [Abstract][Full Text] [Related]
6. Polymorphism of ITPA 94C>A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6-mercaptopurine.
Wan Rosalina WR; Teh LK; Mohamad N; Nasir A; Yusoff R; Baba AA; Salleh MZ
J Clin Pharm Ther; 2012 Apr; 37(2):237-41. PubMed ID: 21545474
[TBL] [Abstract][Full Text] [Related]
7. Genetic variants of thiopurine and folate metabolic pathways determine 6-MP-mediated hematological toxicity in childhood ALL.
Dorababu P; Naushad SM; Linga VG; Gundeti S; Nagesh N; Kutala VK; Reddanna P; Digumarti R
Pharmacogenomics; 2012 Jul; 13(9):1001-8. PubMed ID: 22838948
[TBL] [Abstract][Full Text] [Related]
8. Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?
Zhou H; Li L; Yang P; Yang L; Zheng JE; Zhou Y; Han Y
BMC Cancer; 2018 May; 18(1):516. PubMed ID: 29720126
[TBL] [Abstract][Full Text] [Related]
9. Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.
Stocco G; Crews KR; Evans WE
Expert Opin Drug Saf; 2010 Jan; 9(1):23-37. PubMed ID: 20021291
[TBL] [Abstract][Full Text] [Related]
10. Role of TPMT and ITPA variants in mercaptopurine disposition.
Gerbek T; Ebbesen M; Nersting J; Frandsen TL; Appell ML; Schmiegelow K
Cancer Chemother Pharmacol; 2018 Mar; 81(3):579-586. PubMed ID: 29387964
[TBL] [Abstract][Full Text] [Related]
11. Prevalence of TPMT, ITPA and NUDT 15 genetic polymorphisms and their relation to 6MP toxicity in north Indian children with acute lymphoblastic leukemia.
Khera S; Trehan A; Bhatia P; Singh M; Bansal D; Varma N
Cancer Chemother Pharmacol; 2019 Feb; 83(2):341-348. PubMed ID: 30474703
[TBL] [Abstract][Full Text] [Related]
12. NUDT15 and TPMT genetic polymorphisms are related to 6-mercaptopurine intolerance in children treated for acute lymphoblastic leukemia at the Children's Cancer Center of Lebanon.
Zgheib NK; Akika R; Mahfouz R; Aridi CA; Ghanem KM; Saab R; Abboud MR; Tarek N; El Solh H; Muwakkit SA
Pediatr Blood Cancer; 2017 Jan; 64(1):146-150. PubMed ID: 27577869
[TBL] [Abstract][Full Text] [Related]
13. Influence of age, sex, and haplotypes of thiopurine methyltransferase (TPMT) gene on 6- mercaptopurine toxicity in children with acute lymphoblastic leukemia.
Uppugunduri CR; Ansari M
Eur J Clin Pharmacol; 2012 May; 68(5):887-8; author reply 885-6. PubMed ID: 22166935
[No Abstract] [Full Text] [Related]
14. Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.
Stocco G; Cheok MH; Crews KR; Dervieux T; French D; Pei D; Yang W; Cheng C; Pui CH; Relling MV; Evans WE
Clin Pharmacol Ther; 2009 Feb; 85(2):164-72. PubMed ID: 18685564
[TBL] [Abstract][Full Text] [Related]
15.
Fan POL; Leung KT; Chan KYY; Leung AWK; Lam GKS; Chow TTW; Cheng FWT; Yuen LYP; Moriyama T; Yang JJ; Li CK
Pediatr Hematol Oncol; 2022 Apr; 39(3):254-266. PubMed ID: 34665987
[TBL] [Abstract][Full Text] [Related]
16. Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy.
Adam de Beaumais T; Fakhoury M; Medard Y; Azougagh S; Zhang D; Yakouben K; Jacqz-Aigrain E
Br J Clin Pharmacol; 2011 Apr; 71(4):575-84. PubMed ID: 21395650
[TBL] [Abstract][Full Text] [Related]
17. Frequency of ITPA gene polymorphisms in Iranian patients with acute lymphoblastic leukemia and prediction of its myelosuppressive effects.
Azimi F; Mortazavi Y; Alavi S; Khalili M; Ramazani A
Leuk Res; 2015 Oct; 39(10):1048-54. PubMed ID: 26242828
[TBL] [Abstract][Full Text] [Related]
18. Inosine triphosphate pyrophosphohydrolase (ITPA) polymorphic sequence variants in Chinese ALL children and possible association with mercaptopurine related toxicity.
Ma X; Zheng J; Jin M; Li W; Gao C; Zhang D; Chen Y; Li X; Xie J
Int J Clin Exp Pathol; 2014; 7(7):4552-6. PubMed ID: 25120852
[TBL] [Abstract][Full Text] [Related]
19. Pharmacogenetics of 6-mercaptopurine in a black Zimbabwean cohort treated for acute lymphoblastic leukaemia.
Chikondowa P; Munkombwe D; Chikwambi Z; Kuona P; Masimirembwa C
Pharmacogenomics; 2023 Jun; 24(8):449-457. PubMed ID: 37248698
[TBL] [Abstract][Full Text] [Related]
20. A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.
Skrzypczak-Zielinska M; Borun P; Bartkowiak-Kaczmarek A; Zakerska-Banaszak O; Walczak M; Dobrowolska A; Kurzawski M; Waszak M; Lipinski D; Plawski A; Slomski R
Mol Diagn Ther; 2016 Oct; 20(5):493-9. PubMed ID: 27307154
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]