These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 22017545)

  • 1. Up-regulation of Cks1 and Skp2 with TNFα/NF-κB signaling in chronic progressive nephropathy.
    Suzuki S; Fukasawa H; Misaki T; Togawa A; Ohashi N; Kitagawa K; Kotake Y; Niida H; Hishida A; Yamamoto T; Kitagawa M
    Genes Cells; 2011 Nov; 16(11):1110-20. PubMed ID: 22017545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice.
    Suzuki S; Fukasawa H; Kitagawa K; Uchida C; Hattori T; Isobe T; Oda T; Misaki T; Ohashi N; Nakayama K; Nakayama KI; Hishida A; Yamamoto T; Kitagawa M
    Am J Pathol; 2007 Aug; 171(2):473-83. PubMed ID: 17620370
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
    Bashir T; Dorrello NV; Amador V; Guardavaccaro D; Pagano M
    Nature; 2004 Mar; 428(6979):190-3. PubMed ID: 15014502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
    Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
    Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of the Skp2/p27 axis in the progression of chronic nephropathy.
    Suzuki S; Ohashi N; Kitagawa M
    Cell Mol Life Sci; 2013 Sep; 70(18):3277-87. PubMed ID: 23255047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
    Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
    PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
    Appleman LJ; Chernova I; Li L; Boussiotis VA
    Cell Cycle; 2006 Sep; 5(18):2123-9. PubMed ID: 16969077
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epidermal growth factor upregulates Skp2/Cks1 and p27(kip1) in human extrahepatic cholangiocarcinoma cells.
    Kim JY; Kim HJ; Park JH; Park DI; Cho YK; Sohn CI; Jeon WK; Kim BI; Kim DH; Chae SW; Sohn JH
    World J Gastroenterol; 2014 Jan; 20(3):755-73. PubMed ID: 24574749
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.
    Pavlides SC; Lecanda J; Daubriac J; Pandya UM; Gama P; Blank S; Mittal K; Shukla P; Gold LI
    Cell Cycle; 2016; 15(7):931-47. PubMed ID: 26963853
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
    Uehara N; Yoshizawa K; Tsubura A
    Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of ubiquitin ligase SCF(Skp2) by Cks1: insights from hydrogen exchange mass spectrometry.
    Yao ZP; Zhou M; Kelly SE; Seeliger MA; Robinson CV; Itzhaki LS
    J Mol Biol; 2006 Oct; 363(3):673-86. PubMed ID: 16979657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-cycle regulator Cks1 promotes hepatocellular carcinoma by supporting NF-κB-dependent expression of interleukin-8.
    Lee EK; Kim DG; Kim JS; Yoon Y
    Cancer Res; 2011 Nov; 71(21):6827-35. PubMed ID: 21917729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p27(Kip1) stabilization and G(1) arrest by 1,25-dihydroxyvitamin D(3) in ovarian cancer cells mediated through down-regulation of cyclin E/cyclin-dependent kinase 2 and Skp1-Cullin-F-box protein/Skp2 ubiquitin ligase.
    Li P; Li C; Zhao X; Zhang X; Nicosia SV; Bai W
    J Biol Chem; 2004 Jun; 279(24):25260-7. PubMed ID: 15075339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
    Bornstein G; Ganoth D; Hershko A
    Proc Natl Acad Sci U S A; 2006 Aug; 103(31):11515-20. PubMed ID: 16861300
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
    Rowland RJ; Heath R; Maskell D; Thompson RF; Ranson NA; Blaza JN; Endicott JA; Noble MEM; Salamina M
    Sci Rep; 2023 Jul; 13(1):10718. PubMed ID: 37400515
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
    Mamillapalli R; Gavrilova N; Mihaylova VT; Tsvetkov LM; Wu H; Zhang H; Sun H
    Curr Biol; 2001 Feb; 11(4):263-7. PubMed ID: 11250155
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer.
    Zhao H; Lu Z; Bauzon F; Fu H; Cui J; Locker J; Zhu L
    Oncogene; 2017 Jan; 36(1):60-70. PubMed ID: 27181203
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
    Old JB; Kratzat S; Hoellein A; Graf S; Nilsson JA; Nilsson L; Nakayama KI; Peschel C; Cleveland JL; Keller UB
    Mol Cancer Res; 2010 Mar; 8(3):353-62. PubMed ID: 20197382
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Three different binding sites of Cks1 are required for p27-ubiquitin ligation.
    Sitry D; Seeliger MA; Ko TK; Ganoth D; Breward SE; Itzhaki LS; Pagano M; Hershko A
    J Biol Chem; 2002 Nov; 277(44):42233-40. PubMed ID: 12140288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The amelioration of renal damage in Skp2-deficient mice canceled by p27 Kip1 deficiency in Skp2-/- p27-/- mice.
    Suzuki S; Fukasawa H; Misaki T; Togawa A; Ohashi N; Kitagawa K; Kotake Y; Liu N; Niida H; Nakayama K; Nakayama KI; Yamamoto T; Kitagawa M
    PLoS One; 2012; 7(4):e36249. PubMed ID: 22558406
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.