313 related articles for article (PubMed ID: 22018341)
1. BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells.
Jämsä A; Belda O; Edlund M; Lindström E
J Biomed Sci; 2011 Oct; 18(1):76. PubMed ID: 22018341
[TBL] [Abstract][Full Text] [Related]
2. Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.
Elvang AB; Volbracht C; Pedersen LØ; Jensen KG; Karlsson JJ; Larsen SA; Mørk A; Stensbøl TB; Bastlund JF
J Neurochem; 2009 Sep; 110(5):1377-87. PubMed ID: 19519664
[TBL] [Abstract][Full Text] [Related]
3. Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production.
Strömberg K; Eketjäll S; Georgievska B; Tunblad K; Eliason K; Olsson F; Radesäter AC; Klintenberg R; Arvidsson PI; von Berg S; Fälting J; Cowburn RF; Dabrowski M
FEBS J; 2015 Jan; 282(1):65-73. PubMed ID: 25303711
[TBL] [Abstract][Full Text] [Related]
4. Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage.
Netzer WJ; Bettayeb K; Sinha SC; Flajolet M; Greengard P; Bustos V
Proc Natl Acad Sci U S A; 2017 Feb; 114(6):1389-1394. PubMed ID: 28115709
[TBL] [Abstract][Full Text] [Related]
5. PPAR-α agonist regulates amyloid-β generation via inhibiting BACE-1 activity in human neuroblastoma SH-SY5Y cells transfected with APPswe gene.
Zhang H; Gao Y; Qiao PF; Zhao FL; Yan Y
Mol Cell Biochem; 2015 Oct; 408(1-2):37-46. PubMed ID: 26092426
[TBL] [Abstract][Full Text] [Related]
6. Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.
Hook VY; Toneff T; Aaron W; Yasothornsrikul S; Bundey R; Reisine T
J Neurochem; 2002 Apr; 81(2):237-56. PubMed ID: 12064471
[TBL] [Abstract][Full Text] [Related]
7. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
8. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
[TBL] [Abstract][Full Text] [Related]
9. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
10. Acute effect on the Aβ isoform pattern in CSF in response to γ-secretase modulator and inhibitor treatment in dogs.
Portelius E; Van Broeck B; Andreasson U; Gustavsson MK; Mercken M; Zetterberg H; Borghys H; Blennow K
J Alzheimers Dis; 2010; 21(3):1005-12. PubMed ID: 20634579
[TBL] [Abstract][Full Text] [Related]
11. Identification of a BACE1 Binding Peptide Candidate for the Prevention of Amyloid Beta in Alzheimer's Disease.
Read J; Suphioglu C
Cell Physiol Biochem; 2019; 53(2):413-428. PubMed ID: 31415717
[TBL] [Abstract][Full Text] [Related]
12. Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.
Svedružić ZM; Popović K; Smoljan I; Sendula-Jengić V
PLoS One; 2012; 7(3):e32293. PubMed ID: 22479317
[TBL] [Abstract][Full Text] [Related]
13. Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.
Barnwell E; Padmaraju V; Baranello R; Pacheco-Quinto J; Crosson C; Ablonczy Z; Eckman E; Eckman CB; Ramakrishnan V; Greig NH; Pappolla MA; Sambamurti K
PLoS One; 2014; 9(3):e91531. PubMed ID: 24658363
[TBL] [Abstract][Full Text] [Related]
14. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells.
Li Q; Wu D; Zhang L; Zhang Y
Exp Gerontol; 2010 Nov; 45(11):842-7. PubMed ID: 20600777
[TBL] [Abstract][Full Text] [Related]
15. MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer's disease.
Liu CG; Wang JL; Li L; Wang PC
Int J Mol Med; 2014 Jul; 34(1):160-6. PubMed ID: 24827165
[TBL] [Abstract][Full Text] [Related]
16. BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα.
Owens L; Bracewell J; Benedetto A; Dawson N; Gaffney C; Parkin E
J Alzheimers Dis; 2022; 86(3):1201-1220. PubMed ID: 35180123
[TBL] [Abstract][Full Text] [Related]
17. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
[TBL] [Abstract][Full Text] [Related]
18. X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.
King GD; Cherian K; Turner RS
J Neurochem; 2004 Feb; 88(4):971-82. PubMed ID: 14756819
[TBL] [Abstract][Full Text] [Related]
19. Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers.
Siemers E; Skinner M; Dean RA; Gonzales C; Satterwhite J; Farlow M; Ness D; May PC
Clin Neuropharmacol; 2005; 28(3):126-32. PubMed ID: 15965311
[TBL] [Abstract][Full Text] [Related]
20. Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
Meng P; Yoshida H; Matsumiya T; Imaizumi T; Tanji K; Xing F; Hayakari R; Dempoya J; Tatsuta T; Aizawa-Yashiro T; Mimura J; Kosaka K; Itoh K; Satoh K
Neurosci Res; 2013 Feb; 75(2):94-102. PubMed ID: 23257508
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]