BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

624 related articles for article (PubMed ID: 22020181)

  • 1. Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development.
    Agoram BM; Demin O
    Drug Discov Today; 2011 Dec; 16(23-24):1031-6. PubMed ID: 22020181
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systems pharmacology for drug discovery and development: paradigm shift or flash in the pan?
    Vicini P; van der Graaf PH
    Clin Pharmacol Ther; 2013 May; 93(5):379-81. PubMed ID: 23598453
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Using quantitative systems pharmacology for novel drug discovery.
    PĂ©rez-Nueno VI
    Expert Opin Drug Discov; 2015 Dec; 10(12):1315-31. PubMed ID: 26328768
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [An introduction to QSP modeling for pharmacologists].
    Sayama H; Nagasaka Y; Tabata K
    Nihon Yakurigaku Zasshi; 2019; 154(3):143-150. PubMed ID: 31527365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative pharmacology or pharmacokinetic pharmacodynamic integration should be a vital component in integrative pharmacology.
    Gabrielsson J; Green AR
    J Pharmacol Exp Ther; 2009 Dec; 331(3):767-74. PubMed ID: 19779129
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative Systems Pharmacology: A Case for Disease Models.
    Musante CJ; Ramanujan S; Schmidt BJ; Ghobrial OG; Lu J; Heatherington AC
    Clin Pharmacol Ther; 2017 Jan; 101(1):24-27. PubMed ID: 27709613
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation.
    Ribba B; Grimm HP; Agoram B; Davies MR; Gadkar K; Niederer S; van Riel N; Timmis J; van der Graaf PH
    CPT Pharmacometrics Syst Pharmacol; 2017 Aug; 6(8):496-498. PubMed ID: 28585415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Network pharmacology and drug discovery].
    Wang J; Li XJ
    Sheng Li Ke Xue Jin Zhan; 2011 Aug; 42(4):241-5. PubMed ID: 22066413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative systems pharmacology for shifting the drug discovery and development paradigm.
    Bai JP
    Biopharm Drug Dispos; 2013 Dec; 34(9):475-6. PubMed ID: 24338789
    [No Abstract]   [Full Text] [Related]  

  • 10. Applications of Quantitative Systems Pharmacology in Model-Informed Drug Discovery: Perspective on Impact and Opportunities.
    Bradshaw EL; Spilker ME; Zang R; Bansal L; He H; Jones RDO; Le K; Penney M; Schuck E; Topp B; Tsai A; Xu C; Nijsen MJMA; Chan JR
    CPT Pharmacometrics Syst Pharmacol; 2019 Nov; 8(11):777-791. PubMed ID: 31535440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPS for QSP: A Summary of the ACoP6 Symposium on Quantitative Systems Pharmacology and a Stage for Near-Term Efforts in the Field.
    Musante CJ; Abernethy DR; Allerheiligen SR; Lauffenburger DA; Zager MG
    CPT Pharmacometrics Syst Pharmacol; 2016 Sep; 5(9):449-51. PubMed ID: 27639191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Application of pharmacometrics and quantitative systems pharmacology to cancer therapy: The example of luminal a breast cancer.
    Fleisher B; Brown AN; Ait-Oudhia S
    Pharmacol Res; 2017 Oct; 124():20-33. PubMed ID: 28735000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges.
    Geerts H; Wikswo J; van der Graaf PH; Bai JPF; Gaiteri C; Bennett D; Swalley SE; Schuck E; Kaddurah-Daouk R; Tsaioun K; Pelleymounter M
    CPT Pharmacometrics Syst Pharmacol; 2020 Jan; 9(1):5-20. PubMed ID: 31674729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A model qualification method for mechanistic physiological QSP models to support model-informed drug development.
    Friedrich CM
    CPT Pharmacometrics Syst Pharmacol; 2016 Feb; 5(2):43-53. PubMed ID: 26933515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Systems pharmacology to predict drug toxicity: integration across levels of biological organization.
    Bai JP; Abernethy DR
    Annu Rev Pharmacol Toxicol; 2013; 53():451-73. PubMed ID: 23140241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analytical pharmacology: the impact of numbers on pharmacology.
    Kenakin T; Christopoulos A
    Trends Pharmacol Sci; 2011 Apr; 32(4):189-96. PubMed ID: 21397341
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Survey of Software Tool Utilization and Capabilities for Quantitative Systems Pharmacology: What We Have and What We Need.
    Ermakov S; Schmidt BJ; Musante CJ; Thalhauser CJ
    CPT Pharmacometrics Syst Pharmacol; 2019 Feb; 8(2):62-76. PubMed ID: 30417600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relevance of systems pharmacology in drug discovery.
    Cucurull-Sanchez L; Spink KG; Moschos SA
    Drug Discov Today; 2012 Jul; 17(13-14):665-70. PubMed ID: 22405899
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative systems pharmacology as an extension of PK/PD modeling in CNS research and development.
    Geerts H; Spiros A; Roberts P; Carr R
    J Pharmacokinet Pharmacodyn; 2013 Jun; 40(3):257-65. PubMed ID: 23338980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Network pharmacology: new guidelines for drug discovery].
    Liu AL; Du GH
    Yao Xue Xue Bao; 2010 Dec; 45(12):1472-7. PubMed ID: 21351485
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.