637 related articles for article (PubMed ID: 22020632)
1. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
[TBL] [Abstract][Full Text] [Related]
2. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
3. Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
Bilousova T; Melnik M; Miyoshi E; Gonzalez BL; Poon WW; Vinters HV; Miller CA; Corrada MM; Kawas C; Hatami A; Albay R; Glabe C; Gylys KH
Am J Pathol; 2019 Aug; 189(8):1621-1636. PubMed ID: 31108099
[TBL] [Abstract][Full Text] [Related]
4. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
Pankiewicz JE; Guridi M; Kim J; Asuni AA; Sanchez S; Sullivan PM; Holtzman DM; Sadowski MJ
Acta Neuropathol Commun; 2014 Jun; 2():75. PubMed ID: 24972680
[TBL] [Abstract][Full Text] [Related]
5. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
[TBL] [Abstract][Full Text] [Related]
6. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
Nakamura T; Kawarabayashi T; Ueda T; Shimomura S; Hoshino M; Itoh K; Ihara K; Nakaji S; Takatama M; Ikeda Y; Shoji M
J Alzheimers Dis; 2023; 93(1):333-348. PubMed ID: 36970894
[TBL] [Abstract][Full Text] [Related]
7. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
Butterfield DA; Mattson MP
Neurobiol Dis; 2020 May; 138():104795. PubMed ID: 32036033
[TBL] [Abstract][Full Text] [Related]
8. A flow cytometry-based
Kara E; Marks JD; Roe AD; Commins C; Fan Z; Calvo-Rodriguez M; Wegmann S; Hudry E; Hyman BT
J Biol Chem; 2018 Aug; 293(34):13247-13256. PubMed ID: 29950521
[TBL] [Abstract][Full Text] [Related]
9. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
[TBL] [Abstract][Full Text] [Related]
10. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
Tai LM; Bilousova T; Jungbauer L; Roeske SK; Youmans KL; Yu C; Poon WW; Cornwell LB; Miller CA; Vinters HV; Van Eldik LJ; Fardo DW; Estus S; Bu G; Gylys KH; Ladu MJ
J Biol Chem; 2013 Feb; 288(8):5914-26. PubMed ID: 23293020
[TBL] [Abstract][Full Text] [Related]
11. A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3.
Valencia-Olvera AC; Balu D; Bellur S; McNally T; Saleh Y; Pham D; Ghura S; York J; Johansson JO; LaDu MJ; Tai L
Alzheimers Res Ther; 2023 Dec; 15(1):216. PubMed ID: 38102668
[TBL] [Abstract][Full Text] [Related]
12. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Fitz NF; Cronican AA; Saleem M; Fauq AH; Chapman R; Lefterov I; Koldamova R
J Neurosci; 2012 Sep; 32(38):13125-36. PubMed ID: 22993429
[TBL] [Abstract][Full Text] [Related]
13. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
Aleshkov S; Abraham CR; Zannis VI
Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
[TBL] [Abstract][Full Text] [Related]
14. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention.
Keeney JT; Ibrahimi S; Zhao L
J Alzheimers Dis; 2015; 48(2):411-24. PubMed ID: 26402005
[TBL] [Abstract][Full Text] [Related]
15. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
16. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Deane R; Sagare A; Hamm K; Parisi M; Lane S; Finn MB; Holtzman DM; Zlokovic BV
J Clin Invest; 2008 Dec; 118(12):4002-13. PubMed ID: 19033669
[TBL] [Abstract][Full Text] [Related]
17. The Interplay of Apoes with Syndecans in Influencing Key Cellular Events of Amyloid Pathology.
Hudák A; Jósvay K; Domonkos I; Letoha A; Szilák L; Letoha T
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34209175
[TBL] [Abstract][Full Text] [Related]
18. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
Fryer JD; Simmons K; Parsadanian M; Bales KR; Paul SM; Sullivan PM; Holtzman DM
J Neurosci; 2005 Mar; 25(11):2803-10. PubMed ID: 15772340
[TBL] [Abstract][Full Text] [Related]
19. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.
Hartman RE; Laurer H; Longhi L; Bales KR; Paul SM; McIntosh TK; Holtzman DM
J Neurosci; 2002 Dec; 22(23):10083-7. PubMed ID: 12451108
[TBL] [Abstract][Full Text] [Related]
20. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.
Hashimoto T; Serrano-Pozo A; Hori Y; Adams KW; Takeda S; Banerji AO; Mitani A; Joyner D; Thyssen DH; Bacskai BJ; Frosch MP; Spires-Jones TL; Finn MB; Holtzman DM; Hyman BT
J Neurosci; 2012 Oct; 32(43):15181-92. PubMed ID: 23100439
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
