These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 22021038)

  • 1. Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
    Khanna M; Chen CH; Kimble-Hill A; Parajuli B; Perez-Miller S; Baskaran S; Kim J; Dria K; Vasiliou V; Mochly-Rosen D; Hurley TD
    J Biol Chem; 2011 Dec; 286(50):43486-94. PubMed ID: 22021038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
    Jiménez R; Pequerul R; Amor A; Lorenzo J; Metwally K; Avilés FX; Parés X; Farrés J
    Chem Biol Interact; 2019 Jun; 306():123-130. PubMed ID: 30958995
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance.
    Moreb JS; Ucar D; Han S; Amory JK; Goldstein AS; Ostmark B; Chang LJ
    Chem Biol Interact; 2012 Jan; 195(1):52-60. PubMed ID: 22079344
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
    Parajuli B; Georgiadis TM; Fishel ML; Hurley TD
    Chembiochem; 2014 Mar; 15(5):701-12. PubMed ID: 24677340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes.
    Klyosov AA
    Biochemistry; 1996 Apr; 35(14):4457-67. PubMed ID: 8605195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).
    Yang SM; Yasgar A; Miller B; Lal-Nag M; Brimacombe K; Hu X; Sun H; Wang A; Xu X; Nguyen K; Oppermann U; Ferrer M; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
    J Med Chem; 2015 Aug; 58(15):5967-78. PubMed ID: 26207746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues.
    Rekha GK; Devaraj VR; Sreerama L; Lee MJ; Nagasawa HT; Sladek NE
    Biochem Pharmacol; 1998 Feb; 55(4):465-74. PubMed ID: 9514081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3.
    Giorgianni F; Bridson PK; Sorrentino BP; Pohl J; Blakley RL
    Biochem Pharmacol; 2000 Aug; 60(3):325-38. PubMed ID: 10856427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.
    Buchman CD; Hurley TD
    J Med Chem; 2017 Mar; 60(6):2439-2455. PubMed ID: 28219011
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of Novel Isatin Derivative Bearing a Nitrofuran Moiety as Potent Multi-Isoform Aldehyde Dehydrogenase Inhibitor.
    Gowda K; Raza A; Vangala V; Lone NA; Lin JM; Singh JK; Srivastava SK; Schell TD; Robertson GP; Amin S; Sharma AK
    Molecules; 2024 Jun; 29(13):. PubMed ID: 38999066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.
    Dinavahi SS; Gowda R; Bazewicz CG; Battu MB; Lin JM; Chitren RJ; Pandey MK; Amin S; Robertson GP; Gowda K
    Eur J Med Chem; 2020 Feb; 187():111962. PubMed ID: 31887569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.
    Yang SM; Martinez NJ; Yasgar A; Danchik C; Johansson C; Wang Y; Baljinnyam B; Wang AQ; Xu X; Shah P; Cheff D; Wang XS; Roth J; Lal-Nag M; Dunford JE; Oppermann U; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
    J Med Chem; 2018 Jun; 61(11):4883-4903. PubMed ID: 29767973
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism.
    Klyosov AA; Rashkovetsky LG; Tahir MK; Keung WM
    Biochemistry; 1996 Apr; 35(14):4445-56. PubMed ID: 8605194
    [TBL] [Abstract][Full Text] [Related]  

  • 14. STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe.
    Koenders STA; van Rooden EJ; van den Elst H; Florea BI; Overkleeft HS; van der Stelt M
    Chembiochem; 2020 Jul; 21(13):1911-1917. PubMed ID: 31985142
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application.
    Koppaka V; Thompson DC; Chen Y; Ellermann M; Nicolaou KC; Juvonen RO; Petersen D; Deitrich RA; Hurley TD; Vasiliou V
    Pharmacol Rev; 2012 Jul; 64(3):520-39. PubMed ID: 22544865
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aldehyde dehydrogenases and their role in carcinogenesis.
    Lindahl R
    Crit Rev Biochem Mol Biol; 1992; 27(4-5):283-335. PubMed ID: 1521460
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rat liver constitutive and phenobarbital-inducible cytosolic aldehyde dehydrogenases are highly homologous proteins that function as distinct isozymes.
    Kathmann EC; Naylor S; Lipsky JJ
    Biochemistry; 2000 Sep; 39(36):11170-6. PubMed ID: 10998257
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipid aldehyde oxidation as a physiological role for class 3 aldehyde dehydrogenases.
    Lindahl R; Petersen DR
    Biochem Pharmacol; 1991 Jun; 41(11):1583-7. PubMed ID: 2043148
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aldehyde dehydrogenases and cell proliferation.
    Muzio G; Maggiora M; Paiuzzi E; Oraldi M; Canuto RA
    Free Radic Biol Med; 2012 Feb; 52(4):735-46. PubMed ID: 22206977
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics.
    Dinavahi SS; Bazewicz CG; Gowda R; Robertson GP
    Trends Pharmacol Sci; 2019 Oct; 40(10):774-789. PubMed ID: 31515079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.