BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 22021428)

  • 1. GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer.
    Wang Y; He X; Ngeow J; Eng C
    Hum Mol Genet; 2012 Feb; 21(3):569-76. PubMed ID: 22021428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.
    Wang Y; Romigh T; He X; Orloff MS; Silverman RH; Heston WD; Eng C
    Hum Mol Genet; 2010 Nov; 19(22):4319-29. PubMed ID: 20729295
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells.
    Lin HK; Hu YC; Lee DK; Chang C
    Mol Endocrinol; 2004 Oct; 18(10):2409-23. PubMed ID: 15205473
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers.
    Wang Y; Romigh T; He X; Tan MH; Orloff MS; Silverman RH; Heston WD; Eng C
    Oncogene; 2011 Oct; 30(42):4327-38. PubMed ID: 21532617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.
    Tam KJ; Dalal K; Hsing M; Cheng CW; Khosravi S; Yenki P; Tse C; Peacock JW; Sharma A; Chiang YT; Wang Y; Cherkasov A; Rennie PS; Gleave ME; Ong CJ
    Oncotarget; 2017 Feb; 8(6):9617-9633. PubMed ID: 28038451
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition.
    Lee JY; Kang MB; Jang SH; Qian T; Kim HJ; Kim CH; Kim Y; Kong G
    Oncogene; 2009 Feb; 28(6):824-31. PubMed ID: 19079342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.
    Hjelmeland AB; Hjelmeland MD; Shi Q; Hart JL; Bigner DD; Wang XF; Kontos CD; Rich JN
    Cancer Res; 2005 Dec; 65(24):11276-81. PubMed ID: 16357132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells.
    Ju JH; Yang W; Lee KM; Oh S; Nam K; Shim S; Shin SY; Gye MC; Chu IS; Shin I
    Clin Cancer Res; 2013 Aug; 19(16):4335-46. PubMed ID: 23833298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss.
    Lei Q; Jiao J; Xin L; Chang CJ; Wang S; Gao J; Gleave ME; Witte ON; Liu X; Wu H
    Cancer Cell; 2006 May; 9(5):367-78. PubMed ID: 16697957
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exogenous PTEN gene induces apoptosis in breast carcinoma cell line MDA468.
    Chen Q; Wang C; Jiang C; Chen D
    J Huazhong Univ Sci Technolog Med Sci; 2007 Feb; 27(1):61-4. PubMed ID: 17393112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
    Weng LP; Smith WM; Dahia PL; Ziebold U; Gil E; Lees JA; Eng C
    Cancer Res; 1999 Nov; 59(22):5808-14. PubMed ID: 10582703
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma.
    Tokunaga E; Oki E; Kimura Y; Yamanaka T; Egashira A; Nishida K; Koga T; Morita M; Kakeji Y; Maehara Y
    Breast Cancer Res Treat; 2007 Mar; 101(3):249-57. PubMed ID: 17006756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex.
    He B; Lanz RB; Fiskus W; Geng C; Yi P; Hartig SM; Rajapakshe K; Shou J; Wei L; Shah SS; Foley C; Chew SA; Eedunuri VK; Bedoya DJ; Feng Q; Minami T; Mitsiades CS; Frolov A; Weigel NL; Hilsenbeck SG; Rosen DG; Palzkill T; Ittmann MM; Song Y; Coarfa C; O'Malley BW; Mitsiades N
    Proc Natl Acad Sci U S A; 2014 Dec; 111(51):18261-6. PubMed ID: 25489091
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment.
    Ma Q; Fu W; Li P; Nicosia SV; Jenster G; Zhang X; Bai W
    Mol Endocrinol; 2009 Feb; 23(2):213-25. PubMed ID: 19074551
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth.
    Ghosh-Choudhury N; Mandal CC; Ghosh-Choudhury N; Ghosh Choudhury G
    Cell Signal; 2010 May; 22(5):749-58. PubMed ID: 20060890
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas.
    Wang Y; He X; Yu Q; Eng C
    Hum Mol Genet; 2013 Jun; 22(11):2263-72. PubMed ID: 23418309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S100A4 negatively regulates β-catenin by inducing the Egr-1-PTEN-Akt-GSK3β degradation pathway.
    Yang W; Nam K; Ju JH; Lee KM; Oh S; Shin I
    Cell Signal; 2014 Oct; 26(10):2096-106. PubMed ID: 24975844
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MTDH mediates trastuzumab resistance in HER2 positive breast cancer by decreasing PTEN expression through an NFκB-dependent pathway.
    Du C; Yi X; Liu W; Han T; Liu Z; Ding Z; Zheng Z; Piao Y; Yuan J; Han Y; Xie M; Xie X
    BMC Cancer; 2014 Nov; 14():869. PubMed ID: 25417825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2.
    Seo WY; Jeong BC; Yu EJ; Kim HJ; Kim SH; Lim JE; Kwon GY; Lee HM; Kim JH
    Nucleic Acids Res; 2013 Oct; 41(18):8526-36. PubMed ID: 23887938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.