These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 22023223)

  • 21. X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.
    Saito Y; Sano Y; Vassar R; Gandy S; Nakaya T; Yamamoto T; Suzuki T
    J Biol Chem; 2008 Dec; 283(51):35763-71. PubMed ID: 18845544
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Oxidative stress promotes JNK-dependent amyloidogenic processing of normally expressed human APP by differential modification of alpha-, beta- and gamma-secretase expression.
    Quiroz-Baez R; Rojas E; Arias C
    Neurochem Int; 2009 Dec; 55(7):662-70. PubMed ID: 19560504
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein.
    Irizarry MC; Deng A; Lleo A; Berezovska O; Von Arnim CA; Martin-Rehrmann M; Manelli A; LaDu MJ; Hyman BT; Rebeck GW
    J Neurochem; 2004 Sep; 90(5):1132-43. PubMed ID: 15312168
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Active gamma-secretase is localized to detergent-resistant membranes in human brain.
    Hur JY; Welander H; Behbahani H; Aoki M; Frånberg J; Winblad B; Frykman S; Tjernberg LO
    FEBS J; 2008 Mar; 275(6):1174-87. PubMed ID: 18266764
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
    Lichtenthaler SF; Ida N; Multhaup G; Masters CL; Beyreuther K
    Biochemistry; 1997 Dec; 36(49):15396-403. PubMed ID: 9398269
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Human brain proteins showing neuron-specific interactions with γ-secretase.
    Inoue M; Hur JY; Kihara T; Teranishi Y; Yamamoto NG; Ishikawa T; Wiehager B; Winblad B; Tjernberg LO; Schedin-Weiss S
    FEBS J; 2015 Jul; 282(14):2587-99. PubMed ID: 25893612
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Down-regulation of endogenous amyloid precursor protein processing due to cellular aging.
    Kern A; Roempp B; Prager K; Walter J; Behl C
    J Biol Chem; 2006 Feb; 281(5):2405-13. PubMed ID: 16303768
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue.
    Matsushima T; Saito Y; Elliott JI; Iijima-Ando K; Nishimura M; Kimura N; Hata S; Yamamoto T; Nakaya T; Suzuki T
    J Biol Chem; 2012 Jun; 287(23):19715-24. PubMed ID: 22511769
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.
    Sakurai T; Kaneko K; Okuno M; Wada K; Kashiyama T; Shimizu H; Akagi T; Hashikawa T; Nukina N
    J Cell Biol; 2008 Oct; 183(2):339-52. PubMed ID: 18936252
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.
    Teranishi Y; Hur JY; Gu GJ; Kihara T; Ishikawa T; Nishimura T; Winblad B; Behbahani H; Kamali-Moghaddam M; Frykman S; Tjernberg LO
    Biochem Biophys Res Commun; 2012 Aug; 424(3):476-81. PubMed ID: 22771797
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phosphatidylethanolamine plasmalogen enhances the inhibiting effect of phosphatidylethanolamine on γ-secretase activity.
    Onodera T; Futai E; Kan E; Abe N; Uchida T; Kamio Y; Kaneko J
    J Biochem; 2015 May; 157(5):301-9. PubMed ID: 25409699
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.
    Michaki V; Guix FX; Vennekens K; Munck S; Dingwall C; Davis JB; Townsend DM; Tew KD; Feiguin F; De Strooper B; Dotti CG; Wahle T
    J Biol Chem; 2012 Jan; 287(2):1100-11. PubMed ID: 22086926
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Preferred Endocytosis of Amyloid Precursor Protein from Cholesterol-Enriched Lipid Raft Microdomains.
    Cho YY; Kwon OH; Chung S
    Molecules; 2020 Nov; 25(23):. PubMed ID: 33255194
    [TBL] [Abstract][Full Text] [Related]  

  • 34. KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.
    Jiménez-Garduño AM; Mitkovski M; Alexopoulos IK; Sánchez A; Stühmer W; Pardo LA; Ortega A
    Biochim Biophys Acta; 2014 Mar; 1838(3):921-31. PubMed ID: 24269539
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study.
    Burg VK; Grimm HS; Rothhaar TL; Grösgen S; Hundsdörfer B; Haupenthal VJ; Zimmer VC; Mett J; Weingärtner O; Laufs U; Broersen LM; Tanila H; Vanmierlo T; Lütjohann D; Hartmann T; Grimm MO
    J Neurosci; 2013 Oct; 33(41):16072-87. PubMed ID: 24107941
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
    Chapuis J; Flaig A; Grenier-Boley B; Eysert F; Pottiez V; Deloison G; Vandeputte A; Ayral AM; Mendes T; Desai S; Goate AM; Kauwe JSK; Leroux F; Herledan A; Demiautte F; Bauer C; Checler F; Petersen RC; Blennow K; Zetterberg H; Minthon L; Van Deerlin VM; Lee VM; Shaw LM; Trojanowski JQ; Albert M; Moghekar A; O'Brien R; Peskind ER; Malmanche N; Schellenberg GD; Dourlen P; Song OR; Cruchaga C; Amouyel P; Deprez B; Brodin P; Lambert JC;
    Acta Neuropathol; 2017 Jun; 133(6):955-966. PubMed ID: 27933404
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice.
    Kuehnle K; Ledesma MD; Kalvodova L; Smith AE; Crameri A; Skaanes-Brunner F; Thelen KM; Kulic L; Lütjohann D; Heppner FL; Nitsch RM; Mohajeri MH
    Neurochem Res; 2009 Jun; 34(6):1167-82. PubMed ID: 19115107
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
    Won JS; Im YB; Khan M; Contreras M; Singh AK; Singh I
    J Neurochem; 2008 May; 105(4):1536-49. PubMed ID: 18266936
    [TBL] [Abstract][Full Text] [Related]  

  • 39. New tricks from an old dog: Another synaptotoxic fragment from APP.
    Tyan SH; Koo EH
    Cell Res; 2015 Nov; 25(11):1185-6. PubMed ID: 26503171
    [TBL] [Abstract][Full Text] [Related]  

  • 40. γ-Secretase Partitioning into Lipid Bilayers Remodels Membrane Microdomains after Direct Insertion.
    Barros M; Houlihan WJ; Paresi CJ; Brendel M; Rynearson KD; Lee CW; Prikhodko O; Cregger C; Chang G; Wagner SL; Gilchrist ML; Li YM
    Langmuir; 2020 Jun; 36(23):6569-6579. PubMed ID: 32432881
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.