BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 22023331)

  • 1. Link between allosteric signal transduction and functional dynamics in a multisubunit enzyme: S-adenosylhomocysteine hydrolase.
    Lee Y; Jeong LS; Choi S; Hyeon C
    J Am Chem Soc; 2011 Dec; 133(49):19807-15. PubMed ID: 22023331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Domain motions and the open-to-closed conformational transition of an enzyme: a normal mode analysis of S-adenosyl-L-homocysteine hydrolase.
    Wang M; Borchardt RT; Schowen RL; Kuczera K
    Biochemistry; 2005 May; 44(19):7228-39. PubMed ID: 15882061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution.
    Hu C; Fang J; Borchardt RT; Schowen RL; Kuczera K
    Proteins; 2008 Apr; 71(1):131-43. PubMed ID: 17932938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Allosteric communication in dihydrofolate reductase: signaling network and pathways for closed to occluded transition and back.
    Chen J; Dima RI; Thirumalai D
    J Mol Biol; 2007 Nov; 374(1):250-66. PubMed ID: 17916364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligand-induced formation of transient dimers of mammalian 12/15-lipoxygenase: a key to allosteric behavior of this class of enzymes?
    Ivanov I; Shang W; Toledo L; Masgrau L; Svergun DI; Stehling S; Gómez H; Di Venere A; Mei G; Lluch JM; Skrzypczak-Jankun E; González-Lafont A; Kühn H
    Proteins; 2012 Mar; 80(3):703-12. PubMed ID: 22189720
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for two different mechanisms triggering the change in quaternary structure of the allosteric enzyme, glucosamine-6-phosphate deaminase.
    Bustos-Jaimes I; Ramírez-Costa M; De Anda-Aguilar L; Hinojosa-Ocaña P; Calcagno ML
    Biochemistry; 2005 Feb; 44(4):1127-35. PubMed ID: 15667206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Coupling between global dynamics and signal transduction pathways: a mechanism of allostery for chaperonin GroEL.
    Chennubhotla C; Yang Z; Bahar I
    Mol Biosyst; 2008 Apr; 4(4):287-92. PubMed ID: 18354781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: transition-state stabilization and the avoidance of abortive reactions.
    Yang X; Hu Y; Yin DH; Turner MA; Wang M; Borchardt RT; Howell PL; Kuczera K; Schowen RL
    Biochemistry; 2003 Feb; 42(7):1900-9. PubMed ID: 12590576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allostery wiring diagrams in the transitions that drive the GroEL reaction cycle.
    Tehver R; Chen J; Thirumalai D
    J Mol Biol; 2009 Mar; 387(2):390-406. PubMed ID: 19121324
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
    Huang Y; Komoto J; Konishi K; Takata Y; Ogawa H; Gomi T; Fujioka M; Takusagawa F
    J Mol Biol; 2000 Apr; 298(1):149-62. PubMed ID: 10756111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89.
    Yamada T; Takata Y; Komoto J; Gomi T; Ogawa H; Fujioka M; Takusagawa F
    Int J Biochem Cell Biol; 2005 Nov; 37(11):2417-35. PubMed ID: 16061414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring signal transduction in heteromultimeric protein based on energy dissipation model.
    Ma CW; Xiu ZL; Zeng AP
    J Biomol Struct Dyn; 2015; 33(1):134-46. PubMed ID: 24279729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
    Lee KM; Choi WJ; Lee Y; Lee HJ; Zhao LX; Lee HW; Park JG; Kim HO; Hwang KY; Heo YS; Choi S; Jeong LS
    J Med Chem; 2011 Feb; 54(4):930-8. PubMed ID: 21226494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The active-inactive transition of human thymidylate synthase: targeted molecular dynamics simulations.
    Salo-Ahen OM; Wade RC
    Proteins; 2011 Oct; 79(10):2886-99. PubMed ID: 21905113
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
    Oikonomakos NG; Tsitsanou KE; Zographos SE; Skamnaki VT; Goldmann S; Bischoff H
    Protein Sci; 1999 Oct; 8(10):1930-45. PubMed ID: 10548038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Probing the allosteric mechanism in pyrrolysyl-tRNA synthetase using energy-weighted network formalism.
    Bhattacharyya M; Vishveshwara S
    Biochemistry; 2011 Jul; 50(28):6225-36. PubMed ID: 21650159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.
    Jiao W; Hutton RD; Cross PJ; Jameson GB; Parker EJ
    J Mol Biol; 2012 Jan; 415(4):716-26. PubMed ID: 22154807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the role of the conformational flexibility of the active-site lid on the allosteric kinetics of glucosamine-6-phosphate deaminase.
    Bustos-Jaimes I; Sosa-Peinado A; Rudiño-Piñera E; Horjales E; Calcagno ML
    J Mol Biol; 2002 May; 319(1):183-9. PubMed ID: 12051945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular mechanism of allosteric communication in the human PPARalpha-RXRalpha heterodimer.
    Venäläinen T; Molnár F; Oostenbrink C; Carlberg C; Peräkylä M
    Proteins; 2010 Mar; 78(4):873-87. PubMed ID: 19847917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of S-adenosylhomocysteine hydrolase from the thermophilic bacterium Thermotoga maritima.
    Zheng Y; Chen CC; Ko TP; Xiao X; Yang Y; Huang CH; Qian G; Shao W; Guo RT
    J Struct Biol; 2015 May; 190(2):135-42. PubMed ID: 25791616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.