227 related articles for article (PubMed ID: 22025615)
1. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells.
Nacev BA; Grassi P; Dell A; Haslam SM; Liu JO
J Biol Chem; 2011 Dec; 286(51):44045-44056. PubMed ID: 22025615
[TBL] [Abstract][Full Text] [Related]
2. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling.
Shi W; Nacev BA; Aftab BT; Head S; Rudin CM; Liu JO
J Med Chem; 2011 Oct; 54(20):7363-74. PubMed ID: 21936514
[TBL] [Abstract][Full Text] [Related]
3.
Chandler KB; Leon DR; Kuang J; Meyer RD; Rahimi N; Costello CE
J Biol Chem; 2019 Aug; 294(35):13117-13130. PubMed ID: 31308178
[TBL] [Abstract][Full Text] [Related]
4. Itraconazole inhibits HMEC-1 angiogenesis.
Del Carratore R; Carpi A; Beffy P; Lubrano V; Giorgetti L; Maserti BE; Carluccio MA; Simili M; Iervasi G; Balzan S
Biomed Pharmacother; 2012 Jun; 66(4):312-7. PubMed ID: 22564244
[TBL] [Abstract][Full Text] [Related]
5. VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2.
Zhang Z; Neiva KG; Lingen MW; Ellis LM; Nör JE
Cell Death Differ; 2010 Mar; 17(3):499-512. PubMed ID: 19834490
[TBL] [Abstract][Full Text] [Related]
6. Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.
Bruns AF; Herbert SP; Odell AF; Jopling HM; Hooper NM; Zachary IC; Walker JH; Ponnambalam S
Traffic; 2010 Jan; 11(1):161-74. PubMed ID: 19883397
[TBL] [Abstract][Full Text] [Related]
7. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.
Head SA; Shi WQ; Yang EJ; Nacev BA; Hong SY; Pasunooti KK; Li RJ; Shim JS; Liu JO
ACS Chem Biol; 2017 Jan; 12(1):174-182. PubMed ID: 28103683
[TBL] [Abstract][Full Text] [Related]
8. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.
Head SA; Shi W; Zhao L; Gorshkov K; Pasunooti K; Chen Y; Deng Z; Li RJ; Shim JS; Tan W; Hartung T; Zhang J; Zhao Y; Colombini M; Liu JO
Proc Natl Acad Sci U S A; 2015 Dec; 112(52):E7276-85. PubMed ID: 26655341
[TBL] [Abstract][Full Text] [Related]
9. Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis.
Park SY; Shi X; Pang J; Yan C; Berk BC
Arterioscler Thromb Vasc Biol; 2013 Apr; 33(4):737-43. PubMed ID: 23393387
[TBL] [Abstract][Full Text] [Related]
10. The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling.
Kofler N; Corti F; Rivera-Molina F; Deng Y; Toomre D; Simons M
J Biol Chem; 2018 Mar; 293(13):4805-4817. PubMed ID: 29425100
[TBL] [Abstract][Full Text] [Related]
11. Elements of the Endomucin Extracellular Domain Essential for VEGF-Induced VEGFR2 Activity.
Hu Z; Cano I; Saez-Torres KL; LeBlanc ME; Saint-Geniez M; Ng YS; Argüeso P; D'Amore PA
Cells; 2020 Jun; 9(6):. PubMed ID: 32517158
[TBL] [Abstract][Full Text] [Related]
12. Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis.
Imamaki R; Ogawa K; Kizuka Y; Komi Y; Kojima S; Kotani N; Honke K; Honda T; Taniguchi N; Kitazume S
Oncogene; 2018 Aug; 37(31):4287-4299. PubMed ID: 29717262
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis.
Lin YC; Liu CY; Kannagi R; Yang RB
Arterioscler Thromb Vasc Biol; 2018 May; 38(5):1202-1215. PubMed ID: 29545238
[TBL] [Abstract][Full Text] [Related]
14. Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades.
Lee JH; Choi S; Lee Y; Lee HJ; Kim KH; Ahn KS; Bae H; Lee HJ; Lee EO; Ahn KS; Ryu SY; Lü J; Kim SH
Mol Cancer Ther; 2010 Feb; 9(2):389-99. PubMed ID: 20103598
[TBL] [Abstract][Full Text] [Related]
15. Tumor Progression of Non-Small Cell Lung Cancer Controlled by Albumin and Micellar Nanoparticles of Itraconazole, a Multitarget Angiogenesis Inhibitor.
Zhang L; Liu Z; Yang K; Kong C; Liu C; Chen H; Huang J; Qian F
Mol Pharm; 2017 Dec; 14(12):4705-4713. PubMed ID: 29068216
[TBL] [Abstract][Full Text] [Related]
16. Antiangiogenic Therapeutic Potential of Peptides Derived from the Molecular Motor KIF13B that Transports VEGFR2 to Plasmalemma in Endothelial Cells.
Yamada KH; Kang H; Malik AB
Am J Pathol; 2017 Jan; 187(1):214-224. PubMed ID: 27863212
[TBL] [Abstract][Full Text] [Related]
17. Cholesterol trafficking is required for mTOR activation in endothelial cells.
Xu J; Dang Y; Ren YR; Liu JO
Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4764-9. PubMed ID: 20176935
[TBL] [Abstract][Full Text] [Related]
18. L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways.
Gao F; Vasquez SX; Su F; Roberts S; Shah N; Grijalva V; Imaizumi S; Chattopadhyay A; Ganapathy E; Meriwether D; Johnston B; Anantharamaiah GM; Navab M; Fogelman AM; Reddy ST; Farias-Eisner R
Integr Biol (Camb); 2011 Apr; 3(4):479-89. PubMed ID: 21283904
[TBL] [Abstract][Full Text] [Related]
19. Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway.
Li B; Zhang Y; Yin R; Zhong W; Chen R; Yan J
Mediators Inflamm; 2020; 2020():1649453. PubMed ID: 33162828
[TBL] [Abstract][Full Text] [Related]
20. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis.
Lin YC; Chao TY; Yeh CT; Roffler SR; Kannagi R; Yang RB
Arterioscler Thromb Vasc Biol; 2017 Jan; 37(1):144-155. PubMed ID: 27834687
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
