247 related articles for article (PubMed ID: 22027616)
1. The structure of active opsin as a basis for identification of GPCR agonists by dynamic homology modelling and virtual screening assays.
Schneider M; Wolf S; Schlitter J; Gerwert K
FEBS Lett; 2011 Nov; 585(22):3587-92. PubMed ID: 22027616
[TBL] [Abstract][Full Text] [Related]
2. Modeling GPCR active state conformations: the β(2)-adrenergic receptor.
Simpson LM; Wall ID; Blaney FE; Reynolds CA
Proteins; 2011 May; 79(5):1441-57. PubMed ID: 21337626
[TBL] [Abstract][Full Text] [Related]
3. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
Goetz A; Lanig H; Gmeiner P; Clark T
J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
[TBL] [Abstract][Full Text] [Related]
4. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
5. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
Huber T; Menon S; Sakmar TP
Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
[TBL] [Abstract][Full Text] [Related]
6. Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.
Kooistra AJ; Leurs R; de Esch IJ; de Graaf C
J Chem Inf Model; 2015 May; 55(5):1045-61. PubMed ID: 25848966
[TBL] [Abstract][Full Text] [Related]
7. G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations.
Isberg V; Balle T; Sander T; Jørgensen FS; Gloriam DE
J Chem Inf Model; 2011 Feb; 51(2):315-25. PubMed ID: 21261291
[TBL] [Abstract][Full Text] [Related]
8. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
Evers A; Hessler G; Matter H; Klabunde T
J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
[TBL] [Abstract][Full Text] [Related]
9. Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).
Floquet N; M'Kadmi C; Perahia D; Gagne D; Bergé G; Marie J; Banères JL; Galleyrand JC; Fehrentz JA; Martinez J
J Mol Biol; 2010 Jan; 395(4):769-84. PubMed ID: 19782690
[TBL] [Abstract][Full Text] [Related]
10. PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
[TBL] [Abstract][Full Text] [Related]
11. Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site.
Wolf S; Böckmann M; Höweler U; Schlitter J; Gerwert K
FEBS Lett; 2008 Oct; 582(23-24):3335-42. PubMed ID: 18775703
[TBL] [Abstract][Full Text] [Related]
12. Conformational complexity of G-protein-coupled receptors.
Kobilka BK; Deupi X
Trends Pharmacol Sci; 2007 Aug; 28(8):397-406. PubMed ID: 17629961
[TBL] [Abstract][Full Text] [Related]
13. GPCR structure-based virtual screening approach for CB2 antagonist search.
Chen JZ; Wang J; Xie XQ
J Chem Inf Model; 2007; 47(4):1626-37. PubMed ID: 17580929
[TBL] [Abstract][Full Text] [Related]
14. Protein-based virtual screening of chemical databases. II. Are homology models of G-Protein Coupled Receptors suitable targets?
Bissantz C; Bernard P; Hibert M; Rognan D
Proteins; 2003 Jan; 50(1):5-25. PubMed ID: 12471595
[TBL] [Abstract][Full Text] [Related]
15. Toward the active conformations of rhodopsin and the beta2-adrenergic receptor.
Gouldson PR; Kidley NJ; Bywater RP; Psaroudakis G; Brooks HD; Diaz C; Shire D; Reynolds CA
Proteins; 2004 Jul; 56(1):67-84. PubMed ID: 15162487
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of the ligand-free G-protein-coupled receptor opsin.
Park JH; Scheerer P; Hofmann KP; Choe HW; Ernst OP
Nature; 2008 Jul; 454(7201):183-7. PubMed ID: 18563085
[TBL] [Abstract][Full Text] [Related]
17. From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands.
Kooistra AJ; Roumen L; Leurs R; de Esch IJ; de Graaf C
Methods Enzymol; 2013; 522():279-336. PubMed ID: 23374191
[TBL] [Abstract][Full Text] [Related]
18. Homology modeling of G-protein-coupled receptors with X-ray structures on the rise.
Yarnitzky T; Levit A; Niv MY
Curr Opin Drug Discov Devel; 2010 May; 13(3):317-25. PubMed ID: 20443165
[TBL] [Abstract][Full Text] [Related]
19. Beyond rhodopsin: G protein-coupled receptor structure and modeling incorporating the beta2-adrenergic and adenosine A(2A) crystal structures.
Tebben AJ; Schnur DM
Methods Mol Biol; 2011; 672():359-86. PubMed ID: 20838977
[TBL] [Abstract][Full Text] [Related]
20. Molecular dynamics of a biophysical model for beta2-adrenergic and G protein-coupled receptor activation.
Rubenstein LA; Zauhar RJ; Lanzara RG
J Mol Graph Model; 2006 Dec; 25(4):396-409. PubMed ID: 16574446
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
