236 related articles for article (PubMed ID: 22028822)
1. Modeling pharmacodynamic response to the poly(ADP-Ribose) polymerase inhibitor ABT-888 in human peripheral blood mononuclear cells.
Ji J; Kinders RJ; Zhang Y; Rubinstein L; Kummar S; Parchment RE; Tomaszewski JE; Doroshow JH
PLoS One; 2011; 6(10):e26152. PubMed ID: 22028822
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells.
Feng X; Koh DW
Int J Oncol; 2013 Feb; 42(2):749-56. PubMed ID: 23254695
[TBL] [Abstract][Full Text] [Related]
3. Preclinical modeling of a phase 0 clinical trial: qualification of a pharmacodynamic assay of poly (ADP-ribose) polymerase in tumor biopsies of mouse xenografts.
Kinders RJ; Hollingshead M; Khin S; Rubinstein L; Tomaszewski JE; Doroshow JH; Parchment RE;
Clin Cancer Res; 2008 Nov; 14(21):6877-85. PubMed ID: 18980982
[TBL] [Abstract][Full Text] [Related]
4. Immunohistochemical detection of poly(ADP-ribose) polymerase inhibition by ABT-888 in patients with refractory solid tumors and lymphomas.
Yang SX; Kummar S; Steinberg SM; Murgo AJ; Gutierrez M; Rubinstein L; Nguyen D; Kaur G; Chen AP; Giranda VL; Tomaszewski JE; Doroshow JH;
Cancer Biol Ther; 2009 Nov; 8(21):2004-9. PubMed ID: 19823047
[TBL] [Abstract][Full Text] [Related]
5. Phase 0 clinical trial of the poly (ADP-ribose) polymerase inhibitor ABT-888 in patients with advanced malignancies.
Kummar S; Kinders R; Gutierrez ME; Rubinstein L; Parchment RE; Phillips LR; Ji J; Monks A; Low JA; Chen A; Murgo AJ; Collins J; Steinberg SM; Eliopoulos H; Giranda VL; Gordon G; Helman L; Wiltrout R; Tomaszewski JE; Doroshow JH
J Clin Oncol; 2009 Jun; 27(16):2705-11. PubMed ID: 19364967
[TBL] [Abstract][Full Text] [Related]
6. An enzyme-linked immunosorbent poly(ADP-ribose) polymerase biomarker assay for clinical trials of PARP inhibitors.
Liu X; Palma J; Kinders R; Shi Y; Donawho C; Ellis PA; Rodriguez LE; Colon-Lopez M; Saltarelli M; LeBlond D; Lin CT; Frost DJ; Luo Y; Giranda VL
Anal Biochem; 2008 Oct; 381(2):240-7. PubMed ID: 18674509
[TBL] [Abstract][Full Text] [Related]
7. The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivo.
Palma JP; Rodriguez LE; Bontcheva-Diaz VD; Bouska JJ; Bukofzer G; Colon-Lopez M; Guan R; Jarvis K; Johnson EF; Klinghofer V; Liu X; Olson A; Saltarelli MJ; Shi Y; Stavropoulos JA; Zhu GD; Penning TD; Luo Y; Giranda VL; Rosenberg SH; Frost DJ; Donawho CK
Anticancer Res; 2008; 28(5A):2625-35. PubMed ID: 19035287
[TBL] [Abstract][Full Text] [Related]
8. Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types.
Niu J; Scheuerell C; Mehrotra S; Karan S; Puhalla S; Kiesel BF; Ji J; Chu E; Gopalakrishnan M; Ivaturi V; Gobburu J; Beumer JH
J Clin Pharmacol; 2017 Aug; 57(8):977-987. PubMed ID: 28387939
[TBL] [Abstract][Full Text] [Related]
9. Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials.
Zaremba T; Thomas H; Cole M; Plummer ER; Curtin NJ
Cancer Chemother Pharmacol; 2010 Sep; 66(4):807-12. PubMed ID: 20490796
[TBL] [Abstract][Full Text] [Related]
10. The activity and inhibition of poly(ADP-ribose) polymerase-1 in equine peripheral blood mononuclear cells in vitro.
Douglas HF; Southwood LL; Meyer-Ficca ML; Hart SK; Meyer RG
J Vet Emerg Crit Care (San Antonio); 2015; 25(4):528-37. PubMed ID: 26040949
[TBL] [Abstract][Full Text] [Related]
11. Phase I study of PARP inhibitor ABT-888 in combination with topotecan in adults with refractory solid tumors and lymphomas.
Kummar S; Chen A; Ji J; Zhang Y; Reid JM; Ames M; Jia L; Weil M; Speranza G; Murgo AJ; Kinders R; Wang L; Parchment RE; Carter J; Stotler H; Rubinstein L; Hollingshead M; Melillo G; Pommier Y; Bonner W; Tomaszewski JE; Doroshow JH
Cancer Res; 2011 Sep; 71(17):5626-34. PubMed ID: 21795476
[TBL] [Abstract][Full Text] [Related]
12. Pharmacodynamic analyses in a multi-laboratory network: lessons from the poly(ADP-ribose) assay.
Ferry-Galow KV; Ji J; Kinders RJ; Zhang Y; Czambel RK; Schmitz JC; Herzog J; Evrard YA; Parchment RE
Semin Oncol; 2016 Aug; 43(4):492-500. PubMed ID: 27663481
[TBL] [Abstract][Full Text] [Related]
13. The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy.
Nowsheen S; Bonner JA; Yang ES
Radiother Oncol; 2011 Jun; 99(3):331-8. PubMed ID: 21719137
[TBL] [Abstract][Full Text] [Related]
14. Increased poly(ADP-ribosyl)ation in peripheral leukocytes and the reperfused myocardium tissue of rats with ischemia/reperfusion injury: prevention by 3-aminobenzamide treatment.
Zhang LQ; Qi GX; Jiang DM; Tian W; Zou JL
Shock; 2012 May; 37(5):492-500. PubMed ID: 22266967
[TBL] [Abstract][Full Text] [Related]
15. Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles.
Muñoz-Gámez JA; López Viota J; Barrientos A; Carazo Á; Sanjuán-Nuñez L; Quiles-Perez R; Muñoz-de-Rueda P; Delgado Á; Ruiz-Extremera Á; Salmerón J
Liver Int; 2015 Apr; 35(4):1430-41. PubMed ID: 24821649
[TBL] [Abstract][Full Text] [Related]
16. Efficacy of poly (ADP-ribose) polymerase inhibitor olaparib against head and neck cancer cells: Predictions of drug sensitivity based on PAR-p53-NF-κB interactions.
Kwon M; Jang H; Kim EH; Roh JL
Cell Cycle; 2016 Nov; 15(22):3105-3114. PubMed ID: 27686740
[TBL] [Abstract][Full Text] [Related]
17. A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.
Su JM; Thompson P; Adesina A; Li XN; Kilburn L; Onar-Thomas A; Kocak M; Chyla B; McKeegan E; Warren KE; Goldman S; Pollack IF; Fouladi M; Chen A; Giranda V; Boyett J; Kun L; Blaney SM
Neuro Oncol; 2014 Dec; 16(12):1661-8. PubMed ID: 24908656
[TBL] [Abstract][Full Text] [Related]
18. Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies.
Virág L
Curr Vasc Pharmacol; 2005 Jul; 3(3):209-14. PubMed ID: 16026317
[TBL] [Abstract][Full Text] [Related]
19. Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei.
Schlesinger M; Vilchez Larrea SC; Haikarainen T; Narwal M; Venkannagari H; Flawiá MM; Lehtiö L; Fernández Villamil SH
Parasit Vectors; 2016 Mar; 9():173. PubMed ID: 27007296
[TBL] [Abstract][Full Text] [Related]
20. In vitro effects of poly(ADP-ribose) polymerase inhibitors on the production of tumor necrosis factor-α by interferon- γ - and lipopolysaccharide-stimulated peripheral blood mononuclear cells of horses.
Cacciolatti C; Meyer-Ficca ML; Southwood LL; Meyer RG; Bertolotti L; Zarucco L
Am J Vet Res; 2019 Jul; 80(7):663-669. PubMed ID: 31246122
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]