113 related articles for article (PubMed ID: 22029386)
1. New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.
Marco I; Valhondo M; Martín-Fontecha M; Vázquez-Villa H; Del Río J; Planas A; Sagredo O; Ramos JA; Torrecillas IR; Pardo L; Frechilla D; Benhamú B; López-Rodríguez ML
J Med Chem; 2011 Dec; 54(23):7986-99. PubMed ID: 22029386
[TBL] [Abstract][Full Text] [Related]
2. New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.
Valhondo M; Marco I; Martín-Fontecha M; Vázquez-Villa H; Ramos JA; Berkels R; Lauterbach T; Benhamú B; López-Rodríguez ML
J Med Chem; 2013 Oct; 56(20):7851-61. PubMed ID: 24050112
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.
Medina RA; Sallander J; Benhamú B; Porras E; Campillo M; Pardo L; López-Rodríguez ML
J Med Chem; 2009 Apr; 52(8):2384-92. PubMed ID: 19326916
[TBL] [Abstract][Full Text] [Related]
4. Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-HT transporter and 5-HT1A affinity.
Gilbert AM; Coleman T; Kodah J; Mewshaw RE; Scerni R; Schechter LE; Smith DL; Andree TH
Bioorg Med Chem Lett; 2004 Nov; 14(21):5281-4. PubMed ID: 15454211
[TBL] [Abstract][Full Text] [Related]
5. Discovery of a novel 5-HT(3) antagonist/5-HT(1A) agonist 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878) as an orally bioavailable agent for irritable bowel syndrome.
Asagarasu A; Matsui T; Hayashi H; Tamaoki S; Yamauchi Y; Minato K; Sato M
J Med Chem; 2010 Nov; 53(21):7549-63. PubMed ID: 20931963
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
Prandi A; Franchini S; Manasieva LI; Fossa P; Cichero E; Marucci G; Buccioni M; Cilia A; Pirona L; Brasili L
J Med Chem; 2012 Jan; 55(1):23-36. PubMed ID: 22145629
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Cappelli A; Manini M; Valenti S; Castriconi F; Giuliani G; Anzini M; Brogi S; Butini S; Gemma S; Campiani G; Giorgi G; Mennuni L; Lanza M; Giordani A; Caselli G; Letari O; Makovec F
Eur J Med Chem; 2013 May; 63():85-94. PubMed ID: 23466604
[TBL] [Abstract][Full Text] [Related]
8. 1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
Franchini S; Prandi A; Baraldi A; Sorbi C; Tait A; Buccioni M; Marucci G; Cilia A; Pirona L; Fossa P; Cichero E; Brasili L
Eur J Med Chem; 2010 Sep; 45(9):3740-51. PubMed ID: 20605276
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, SAR studies, and evaluation of 1,4-benzoxazepine derivatives as selective 5-HT1A receptor agonists with neuroprotective effect: Discovery of Piclozotan.
Kamei K; Maeda N; Nomura K; Shibata M; Katsuragi-Ogino R; Koyama M; Nakajima M; Inoue T; Ohno T; Tatsuoka T
Bioorg Med Chem; 2006 Mar; 14(6):1978-92. PubMed ID: 16290165
[TBL] [Abstract][Full Text] [Related]
10. New pyridobenzoxazepine derivatives derived from 5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): chemical synthesis and pharmacological evaluation.
Liégeois JF; Deville M; Dilly S; Lamy C; Mangin F; Résimont M; Tarazi FI
J Med Chem; 2012 Feb; 55(4):1572-82. PubMed ID: 22268448
[TBL] [Abstract][Full Text] [Related]
11. Neuroprotective effects of serotonin 5-HT 1A receptor activation against ischemic cell damage in gerbil hippocampus: Involvement of NMDA receptor NR1 subunit and BDNF.
Salazar-Colocho P; Del Río J; Frechilla D
Brain Res; 2008 Mar; 1199():159-66. PubMed ID: 18269931
[TBL] [Abstract][Full Text] [Related]
12. Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides.
Filla SA; Mathes BM; Johnson KW; Phebus LA; Cohen ML; Nelson DL; Zgombick JM; Erickson JA; Schenck KW; Wainscott DB; Branchek TA; Schaus JM
J Med Chem; 2003 Jul; 46(14):3060-71. PubMed ID: 12825944
[TBL] [Abstract][Full Text] [Related]
13. Blockade of 5-HT(3) receptor with MDL 72222 and Y 25130 reduces beta-amyloid protein (25--35)-induced neurotoxicity in cultured rat cortical neurons.
Ju Yeon Ban ; Yeon Hee Seong
Eur J Pharmacol; 2005 Sep; 520(1-3):12-21. PubMed ID: 16150439
[TBL] [Abstract][Full Text] [Related]
14. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.
Herold F; Chodkowski A; Izbicki Ł; Turło J; Dawidowski M; Kleps J; Nowak G; Stachowicz K; Dybała M; Siwek A; Mazurek AP; Mazurek A; Pluciński F
Eur J Med Chem; 2011 Jan; 46(1):142-9. PubMed ID: 21093118
[TBL] [Abstract][Full Text] [Related]
15. Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity.
Heinrich T; Böttcher H; Schiemann K; Hölzemann G; Schwarz M; Bartoszyk GD; van Amsterdam C; Greiner HE; Seyfried CA
Bioorg Med Chem; 2004 Sep; 12(18):4843-52. PubMed ID: 15336263
[TBL] [Abstract][Full Text] [Related]
16. Neuroprotective effect of 5-HT1A receptor agonist, Bay X 3702, demonstrated in vitro and in vivo.
Semkova I; Wolz P; Krieglstein J
Eur J Pharmacol; 1998 Oct; 359(2-3):251-60. PubMed ID: 9832397
[TBL] [Abstract][Full Text] [Related]
17. Molecular modeling of the 3D structure of 5-HT(1A)R: discovery of novel 5-HT(1A)R agonists via dynamic pharmacophore-based virtual screening.
Xu L; Zhou S; Yu K; Gao B; Jiang H; Zhen X; Fu W
J Chem Inf Model; 2013 Dec; 53(12):3202-11. PubMed ID: 24245825
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist.
Picard M; Morisset S; Cloix JF; Bizot JC; Guerin M; Beneteau V; Guillaumet G; Hevor TK
Neuroscience; 2010 Sep; 169(3):1337-46. PubMed ID: 20580787
[TBL] [Abstract][Full Text] [Related]
19. The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist.
Rënyi L; Evenden JL; Fowler CJ; Jerning E; Kelder D; Lake-Bakaar D; Larsson LG; Mohell N; Sällemark M; Ross SB
J Pharmacol Exp Ther; 2001 Dec; 299(3):883-93. PubMed ID: 11714872
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and pharmacological evaluation of [(4-arylpiperazin-1-yl)-alkyl]-carbamic acid ethyl ester derivatives as potential anxiolytic agents.
Khatri M; Rai SK; Ranbhor R; Kishore K; Tiwari M
Arch Pharm Res; 2012 Jul; 35(7):1143-52. PubMed ID: 22864736
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]