126 related articles for article (PubMed ID: 22033481)
1. Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.
Bigalke JM; Dames SA; Blankenfeldt W; Grzesiek S; Geyer M
J Mol Biol; 2011 Dec; 414(5):639-53. PubMed ID: 22033481
[TBL] [Abstract][Full Text] [Related]
2. A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
Schönichen A; Bigalke JM; Urbanke C; Grzesiek S; Dames SA; Geyer M
Biochemistry; 2010 Apr; 49(14):3083-91. PubMed ID: 20210365
[TBL] [Abstract][Full Text] [Related]
3. Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Dames SA; Schönichen A; Schulte A; Barboric M; Peterlin BM; Grzesiek S; Geyer M
Proc Natl Acad Sci U S A; 2007 Sep; 104(36):14312-7. PubMed ID: 17724342
[TBL] [Abstract][Full Text] [Related]
4. Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA.
Czudnochowski N; Vollmuth F; Baumann S; Vogel-Bachmayr K; Geyer M
J Mol Biol; 2010 Jan; 395(1):28-41. PubMed ID: 19883659
[TBL] [Abstract][Full Text] [Related]
5. A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb.
Yik JH; Chen R; Pezda AC; Samford CS; Zhou Q
Mol Cell Biol; 2004 Jun; 24(12):5094-105. PubMed ID: 15169877
[TBL] [Abstract][Full Text] [Related]
6. Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb.
Blazek D; Barboric M; Kohoutek J; Oven I; Peterlin BM
Nucleic Acids Res; 2005; 33(22):7000-10. PubMed ID: 16377779
[TBL] [Abstract][Full Text] [Related]
7. Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor.
Michels AA; Fraldi A; Li Q; Adamson TE; Bonnet F; Nguyen VT; Sedore SC; Price JP; Price DH; Lania L; Bensaude O
EMBO J; 2004 Jul; 23(13):2608-19. PubMed ID: 15201869
[TBL] [Abstract][Full Text] [Related]
8. Regulation of polymerase II transcription by 7SK snRNA: two distinct RNA elements direct P-TEFb and HEXIM1 binding.
Egloff S; Van Herreweghe E; Kiss T
Mol Cell Biol; 2006 Jan; 26(2):630-42. PubMed ID: 16382153
[TBL] [Abstract][Full Text] [Related]
9. Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.
Li Q; Price JP; Byers SA; Cheng D; Peng J; Price DH
J Biol Chem; 2005 Aug; 280(31):28819-26. PubMed ID: 15965233
[TBL] [Abstract][Full Text] [Related]
10. Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat.
Schulte A; Czudnochowski N; Barboric M; Schönichen A; Blazek D; Peterlin BM; Geyer M
J Biol Chem; 2005 Jul; 280(26):24968-77. PubMed ID: 15855166
[TBL] [Abstract][Full Text] [Related]
11. Sequence comparisons of intermediate filament chains: evidence of a unique functional/structural role for coiled-coil segment 1A and linker L1.
Smith TA; Strelkov SV; Burkhard P; Aebi U; Parry DA
J Struct Biol; 2002; 137(1-2):128-45. PubMed ID: 12064940
[TBL] [Abstract][Full Text] [Related]
12. Hexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters.
Kohoutek J; Blazek D; Peterlin BM
Proc Natl Acad Sci U S A; 2006 Nov; 103(46):17349-54. PubMed ID: 17088550
[TBL] [Abstract][Full Text] [Related]
13. HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.
Shimizu N; Ouchida R; Yoshikawa N; Hisada T; Watanabe H; Okamoto K; Kusuhara M; Handa H; Morimoto C; Tanaka H
Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8555-60. PubMed ID: 15941832
[TBL] [Abstract][Full Text] [Related]
14. Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression.
Yoshikawa N; Shimizu N; Sano M; Ohnuma K; Iwata S; Hosono O; Fukuda K; Morimoto C; Tanaka H
Biochem Biophys Res Commun; 2008 Jun; 371(1):44-9. PubMed ID: 18407829
[TBL] [Abstract][Full Text] [Related]
15. Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.
Mbonye UR; Wang B; Gokulrangan G; Chance MR; Karn J
Proteomics; 2015 Jun; 15(12):2078-86. PubMed ID: 25900325
[TBL] [Abstract][Full Text] [Related]
16. HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening.
Fujimoto Y; Nakamura Y; Ohuchi S
Biochimie; 2012 Sep; 94(9):1900-9. PubMed ID: 22609015
[TBL] [Abstract][Full Text] [Related]
17. Inhibiting lentiviral replication by HEXIM1, a cellular negative regulator of the CDK9/cyclin T complex.
Shimizu S; Urano E; Futahashi Y; Miyauchi K; Isogai M; Matsuda Z; Nohtomi K; Onogi T; Takebe Y; Yamamoto N; Komano J
AIDS; 2007 Mar; 21(5):575-82. PubMed ID: 17314519
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
Day CL; Alber T
J Mol Biol; 2000 Aug; 301(1):147-56. PubMed ID: 10926498
[TBL] [Abstract][Full Text] [Related]
19. Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb.
Van Herreweghe E; Egloff S; Goiffon I; Jády BE; Froment C; Monsarrat B; Kiss T
EMBO J; 2007 Aug; 26(15):3570-80. PubMed ID: 17611602
[TBL] [Abstract][Full Text] [Related]
20. Cyclin T1 but not cyclin T2a is induced by a post-transcriptional mechanism in PAMP-activated monocyte-derived macrophages.
Liou LY; Haaland RE; Herrmann CH; Rice AP
J Leukoc Biol; 2006 Feb; 79(2):388-96. PubMed ID: 16330531
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
