These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
280 related articles for article (PubMed ID: 22036506)
1. The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1. Torrino S; Visvikis O; Doye A; Boyer L; Stefani C; Munro P; Bertoglio J; Gacon G; Mettouchi A; Lemichez E Dev Cell; 2011 Nov; 21(5):959-65. PubMed ID: 22036506 [TBL] [Abstract][Full Text] [Related]
2. Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1. Mettouchi A; Lemichez E Small GTPases; 2012; 3(2):102-6. PubMed ID: 22790197 [TBL] [Abstract][Full Text] [Related]
3. The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation. Castillo-Lluva S; Tan CT; Daugaard M; Sorensen PH; Malliri A Oncogene; 2013 Mar; 32(13):1735-42. PubMed ID: 22614015 [TBL] [Abstract][Full Text] [Related]
4. Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation. Andrio E; Lotte R; Hamaoui D; Cherfils J; Doye A; Daugaard M; Sorensen PH; Bost F; Ruimy R; Mettouchi A; Lemichez E Sci Rep; 2017 Mar; 7():44779. PubMed ID: 28317937 [TBL] [Abstract][Full Text] [Related]
5. Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination. Acosta MI; Urbach S; Doye A; Ng YW; Boudeau J; Mettouchi A; Debant A; Manser E; Visvikis O; Lemichez E Sci Rep; 2018 Jan; 8(1):1410. PubMed ID: 29362425 [TBL] [Abstract][Full Text] [Related]
6. HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity. Kumar B; Roy A; Asha K; Sharma-Walia N; Ansari MA; Chandran B J Virol; 2019 May; 93(9):. PubMed ID: 30787155 [TBL] [Abstract][Full Text] [Related]
7. HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models. Zang CX; Wang L; Yang HY; Shang JM; Liu H; Zhang ZH; Ju C; Yuan FY; Li FY; Bao XQ; Zhang D Acta Pharmacol Sin; 2022 Feb; 43(2):285-294. PubMed ID: 34593974 [TBL] [Abstract][Full Text] [Related]
8. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes. Turgu B; El-Naggar A; Kogler M; Tortola L; Zhang HF; Hassan M; Lizardo MM; Kung SH; Lam W; Penninger JM; Sorensen PH EMBO Rep; 2023 Dec; 24(12):e56815. PubMed ID: 37846480 [TBL] [Abstract][Full Text] [Related]
12. Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex. Lachance V; Degrandmaison J; Marois S; Robitaille M; Génier S; Nadeau S; Angers S; Parent JL J Cell Sci; 2014 Jan; 127(Pt 1):111-23. PubMed ID: 24190883 [TBL] [Abstract][Full Text] [Related]
13. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169 [TBL] [Abstract][Full Text] [Related]
14. Ubiquitin-independent proteasomal degradation of Spindlin-1 by the E3 ligase HACE1 contributes to cell-cell adhesion. Palicharla VR; Gupta D; Bhattacharya D; Maddika S FEBS Lett; 2021 Feb; 595(4):491-506. PubMed ID: 33421097 [TBL] [Abstract][Full Text] [Related]
15. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells. Kim I; Shin SH; Lee JE; Park JW Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265 [TBL] [Abstract][Full Text] [Related]
16. Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Düring J; Wolter M; Toplak JJ; Torres C; Dybkov O; Fokkens TJ; Bohnsack KE; Urlaub H; Steinchen W; Dienemann C; Lorenz S Nat Struct Mol Biol; 2024 Feb; 31(2):364-377. PubMed ID: 38332367 [TBL] [Abstract][Full Text] [Related]
17. Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. Singh S; Machida S; Tulsian NK; Choong YK; Ng J; Shankar S; Liu Y; Chandiramani KV; Shi J; Sivaraman J Adv Sci (Weinh); 2023 Sep; 10(27):e2207672. PubMed ID: 37537642 [TBL] [Abstract][Full Text] [Related]
18. Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division. Petracchini S; Hamaoui D; Doye A; Asnacios A; Fage F; Vitiello E; Balland M; Janel S; Lafont F; Gupta M; Ladoux B; Gilleron J; Maia TM; Impens F; Gagnoux-Palacios L; Daugaard M; Sorensen PH; Lemichez E; Mettouchi A Nat Commun; 2022 Oct; 13(1):6059. PubMed ID: 36229487 [TBL] [Abstract][Full Text] [Related]
19. HACE1 is a potential tumor suppressor in osteosarcoma. El-Naggar AM; Clarkson PW; Negri GL; Turgu B; Zhang F; Anglesio MS; Sorensen PH Cell Death Dis; 2019 Jan; 10(1):21. PubMed ID: 30622235 [TBL] [Abstract][Full Text] [Related]
20. Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression. Goka ET; Lippman ME Oncogene; 2015 Oct; 34(42):5395-405. PubMed ID: 25659579 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]