BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 22038515)

  • 1. Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions.
    Chu KY; Li H; Wada K; Johnson JD
    Diabetologia; 2012 Jan; 55(1):128-40. PubMed ID: 22038515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
    Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
    J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy.
    Costes S; Gurlo T; Rivera JF; Butler PC
    Autophagy; 2014 Jun; 10(6):1004-14. PubMed ID: 24879150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo.
    Ittner AA; Bertz J; Chan TY; van Eersel J; Polly P; Ittner LM
    Diabetologia; 2014 Jul; 57(7):1410-9. PubMed ID: 24733160
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System.
    Litwak SA; Wali JA; Pappas EG; Saadi H; Stanley WJ; Varanasi LC; Kay TW; Thomas HE; Gurzov EN
    J Diabetes Res; 2015; 2015():280615. PubMed ID: 26064977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity.
    Vasu S; Moffett RC; McClenaghan NH; Flatt PR
    Exp Cell Res; 2015 Aug; 336(1):100-8. PubMed ID: 26027945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the Translocon.
    Cassel R; Ducreux S; Alam MR; Dingreville F; Berlé C; Burda-Jacob K; Chauvin MA; Chikh K; Païta L; Al-Mawla R; Crola Da Silva C; Rieusset J; Thivolet C; Van Coppenolle F; Madec AM
    PLoS One; 2016; 11(2):e0148686. PubMed ID: 26862742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
    Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
    J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance.
    Akerfeldt MC; Laybutt DR
    Diabetes; 2011 Oct; 60(10):2506-14. PubMed ID: 21940780
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KCNH6 protects pancreatic β-cells from endoplasmic reticulum stress and apoptosis.
    Lu J; Shen H; Li Q; Xiong F; Xie R; Yuan M; Yang JK
    FASEB J; 2020 Nov; 34(11):15015-15028. PubMed ID: 32918525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
    Cunha DA; Igoillo-Esteve M; Gurzov EN; Germano CM; Naamane N; Marhfour I; Fukaya M; Vanderwinden JM; Gysemans C; Mathieu C; Marselli L; Marchetti P; Harding HP; Ron D; Eizirik DL; Cnop M
    Diabetes; 2012 Nov; 61(11):2763-75. PubMed ID: 22773666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Novel Role for Somatostatin in the Survival of Mouse Pancreatic Beta Cells.
    Damsteegt EL; Hassan Z; Hewawasam NV; Sarnsamak K; Jones PM; Hauge-Evans AC
    Cell Physiol Biochem; 2019; 52(3):486-502. PubMed ID: 30873823
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis.
    Xiong X; Sun X; Wang Q; Qian X; Zhang Y; Pan X; Dong XC
    J Endocrinol; 2016 Nov; 231(2):159-165. PubMed ID: 27601447
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Palmitic acid-rich diet suppresses glucose-stimulated insulin secretion (GSIS) and induces endoplasmic reticulum (ER) stress in pancreatic islets in mice.
    Hirata T; Kawai T; Hirose H; Tanaka K; Kurosawa H; Fujii C; Fujita H; Seto Y; Matsumoto H; Itoh H
    Endocr Res; 2016; 41(1):8-15. PubMed ID: 26167855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endoplasmic reticulum stress contributes to NMDA-induced pancreatic β-cell dysfunction in a CHOP-dependent manner.
    Huang XT; Liu W; Zhou Y; Sun M; Sun CC; Zhang CY; Tang SY
    Life Sci; 2019 Sep; 232():116612. PubMed ID: 31260687
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis.
    Bachar E; Ariav Y; Cerasi E; Kaiser N; Leibowitz G
    Diabetologia; 2010 Oct; 53(10):2177-87. PubMed ID: 20596694
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking.
    Boslem E; MacIntosh G; Preston AM; Bartley C; Busch AK; Fuller M; Laybutt DR; Meikle PJ; Biden TJ
    Biochem J; 2011 Apr; 435(1):267-76. PubMed ID: 21265737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
    Xie T; So WY; Li XY; Leung PS
    Clin Sci (Lond); 2019 Oct; 133(19):2029-2044. PubMed ID: 31654570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
    Hu Y; Qi C; Shi J; Tan W; Adiljan Abdurusul ; Zhao Z; Xu Y; Wu H; Zhang Z
    Cell Mol Life Sci; 2023 Mar; 80(4):106. PubMed ID: 36952018
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.