172 related articles for article (PubMed ID: 22040095)
1. Microfluidic electrochemical array for detection of reactive metabolites formed by cytochrome P450 enzymes.
Wasalathanthri DP; Mani V; Tang CK; Rusling JF
Anal Chem; 2011 Dec; 83(24):9499-506. PubMed ID: 22040095
[TBL] [Abstract][Full Text] [Related]
2. Screening reactive metabolites bioactivated by multiple enzyme pathways using a multiplexed microfluidic system.
Wasalathanthri DP; Faria RC; Malla S; Joshi AA; Schenkman JB; Rusling JF
Analyst; 2013 Jan; 138(1):171-8. PubMed ID: 23095952
[TBL] [Abstract][Full Text] [Related]
3. High-throughput metabolic genotoxicity screening with a fluidic microwell chip and electrochemiluminescence.
Wasalathanthri DP; Malla S; Bist I; Tang CK; Faria RC; Rusling JF
Lab Chip; 2013 Dec; 13(23):4554-62. PubMed ID: 24113555
[TBL] [Abstract][Full Text] [Related]
4. Evaluating Metabolite-Related DNA Oxidation and Adduct Damage from Aryl Amines Using a Microfluidic ECL Array.
Bist I; Bhakta S; Jiang D; Keyes TE; Martin A; Forster RJ; Rusling JF
Anal Chem; 2017 Nov; 89(22):12441-12449. PubMed ID: 29083162
[TBL] [Abstract][Full Text] [Related]
5. Differences in metabolite-mediated toxicity of tamoxifen in rodents versus humans elucidated with DNA/microsome electro-optical arrays and nanoreactors.
Zhao L; Krishnan S; Zhang Y; Schenkman JB; Rusling JF
Chem Res Toxicol; 2009 Feb; 22(2):341-7. PubMed ID: 19166339
[TBL] [Abstract][Full Text] [Related]
6. Microfluidic array for simultaneous detection of DNA oxidation and DNA-adduct damage.
Song B; Shen M; Jiang D; Malla S; Mosa IM; Choudhary D; Rusling JF
Analyst; 2016 Oct; 141(20):5722-5729. PubMed ID: 27517117
[TBL] [Abstract][Full Text] [Related]
7. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
[TBL] [Abstract][Full Text] [Related]
8. Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films.
Zhou L; Yang J; Estavillo C; Stuart JD; Schenkman JB; Rusling JF
J Am Chem Soc; 2003 Feb; 125(5):1431-6. PubMed ID: 12553846
[TBL] [Abstract][Full Text] [Related]
9. Electrochemical Activation of the Natural Catalytic Cycle of Cytochrome P450s in Human Liver Microsomes.
Wasalathanthri DP; Malla S; Faria RC; Rusling JF
Electroanalysis; 2012 Nov; 24(11):2049-2052. PubMed ID: 23626453
[TBL] [Abstract][Full Text] [Related]
10. Square wave voltammetric detection of chemical DNA damage with catalytic poly(4-vinylpyridine)-Ru(bpy)2(2+) films.
Mugweru A; Rusling JF
Anal Chem; 2002 Aug; 74(16):4044-9. PubMed ID: 12199572
[TBL] [Abstract][Full Text] [Related]
11. Synergistic metabolic toxicity screening using microsome/DNA electrochemiluminescent arrays and nanoreactors.
Krishnan S; Hvastkovs EG; Bajrami B; Choudhary D; Schenkman JB; Rusling JF
Anal Chem; 2008 Jul; 80(14):5279-85. PubMed ID: 18563913
[TBL] [Abstract][Full Text] [Related]
12. Comparison of DNA-Reactive Metabolites from Nitrosamine and Styrene Using Voltammetric DNA/Microsomes Sensors.
Krishnan S; Bajrami B; Mani V; Pan S; Rusling JF
Electroanalysis; 2009 May; 21(9):1005-1013. PubMed ID: 23100998
[TBL] [Abstract][Full Text] [Related]
13. Examination of microsomal cytochrome P450-catalyzed in vitro activation of o-phenylphenol to DNA binding metabolite(s) by 32P-postlabeling technique.
Pathak DN; Roy D
Carcinogenesis; 1992 Sep; 13(9):1593-7. PubMed ID: 1394845
[TBL] [Abstract][Full Text] [Related]
14. Protein film electrochemistry of microsomes genetically enriched in human cytochrome p450 monooxygenases.
Sultana N; Schenkman JB; Rusling JF
J Am Chem Soc; 2005 Oct; 127(39):13460-1. PubMed ID: 16190685
[TBL] [Abstract][Full Text] [Related]
15. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.
Arlt VM; Stiborova M; Hewer A; Schmeiser HH; Phillips DH
Cancer Res; 2003 Jun; 63(11):2752-61. PubMed ID: 12782579
[TBL] [Abstract][Full Text] [Related]
16. Voltammetric sensor for chemical toxicity using [Ru(bpy)2poly(4-vinylpyridine)10Cl)+ as catalyst in ultrathin films. DNA damage from methylating agents and an enzyme-generated epoxide.
Wang B; Rusling JF
Anal Chem; 2003 Aug; 75(16):4229-35. PubMed ID: 14632140
[TBL] [Abstract][Full Text] [Related]
17. Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays.
Krishnan S; Hvastkovs EG; Bajrami B; Schenkman JB; Rusling JF
Mol Biosyst; 2009 Feb; 5(2):163-9. PubMed ID: 19156262
[TBL] [Abstract][Full Text] [Related]
18. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
19. 3-Methylcholanthrene-inducible liver cytochrome(s) P450 in female Sprague-Dawley rats: possible link between P450 turnover and formation of DNA adducts and I-compounds.
Moorthy B; Chen S; Li D; Randerath K
Carcinogenesis; 1993 May; 14(5):879-86. PubMed ID: 8504481
[TBL] [Abstract][Full Text] [Related]
20. DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites.
Pereg D; Robertson LW; Gupta RC
Chem Biol Interact; 2002 Feb; 139(2):129-44. PubMed ID: 11823002
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]