These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 22041073)

  • 1. Discovery of a novel acyl-CoA: cholesterol acyltransferase inhibitor: the synthesis, biological evaluation, and reduced adrenal toxicity of (4-phenylcoumarin)acetanilide derivatives with a carboxylic acid moiety.
    Ogino M; Nakada Y; Negoro N; Itokawa S; Nishimura S; Sanada T; Satomi T; Kita S; Kubo K; Marui S
    Chem Pharm Bull (Tokyo); 2011; 59(11):1369-75. PubMed ID: 22041073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a potent and orally available acyl-CoA: cholesterol acyltransferase inhibitor as an anti-atherosclerotic agent: (4-phenylcoumarin)acetanilide derivatives.
    Ogino M; Fukui S; Nakada Y; Tokunoh R; Itokawa S; Kakoi Y; Nishimura S; Sanada T; Fuse H; Kubo K; Wada T; Marui S
    Chem Pharm Bull (Tokyo); 2011; 59(10):1268-73. PubMed ID: 21963637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
    O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
    J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.
    Trivedi BK; Purchase TS; Holmes A; Augelli-Szafran CE; Essenburg AD; Hamelehle KL; Stanfield RL; Bousley RF; Krause BR
    J Med Chem; 1994 May; 37(11):1652-9. PubMed ID: 8201599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel indoline-based acyl-CoA:cholesterol acyltransferase inhibitor with antiperoxidative activity: improvement of physicochemical properties and biological activities by introduction of carboxylic acid.
    Takahashi K; Kasai M; Ohta M; Shoji Y; Kunishiro K; Kanda M; Kurahashi K; Shirahase H
    J Med Chem; 2008 Aug; 51(15):4823-33. PubMed ID: 18620381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas.
    Tanaka A; Terasawa T; Hagihara H; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
    J Med Chem; 1998 Jun; 41(13):2390-410. PubMed ID: 9632372
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands.
    Tanaka A; Terasawa T; Hagihara H; Ishibe N; Sawada M; Sakuma Y; Hashimoto M; Takasugi H; Tanaka H
    J Med Chem; 1998 Oct; 41(22):4408-20. PubMed ID: 9784116
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and structure-activity relationship studies of novel 4,4-bis(trifluoromethyl)imidazolines as acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors and antihypercholesterolemic agents.
    Li HY; DeLucca I; Boswell GA; Billheimer JT; Drummond S; Gillies PJ; Robinson C
    Bioorg Med Chem; 1997 Jul; 5(7):1345-61. PubMed ID: 9377095
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heterocyclic amides: inhibitors of acyl-CoA:cholesterol O-acyl transferase with hypocholesterolemic activity in several species and antiatherosclerotic activity in the rabbit.
    White AD; Purchase CF; Picard JA; Anderson MK; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Krause BR; Lee P; Stanfield RL; Reindel JF
    J Med Chem; 1996 Sep; 39(20):3908-19. PubMed ID: 8831757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
    Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
    Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor.
    Junquero D; Oms P; Carilla-Durand E; Autin J; Tarayre J; Degryse A; Patoiseau J; Colpaert FC; Delhon A
    Biochem Pharmacol; 2001 Jan; 61(1):97-108. PubMed ID: 11137714
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.
    Shoji Y; Takahashi K; Ohta M; Kasai M; Kunishiro K; Kanda M; Yogai S; Takeuchi Y; Shirahase H
    Bioorg Med Chem; 2009 Aug; 17(16):6020-31. PubMed ID: 19608421
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.
    Lee HT; Roark WH; Picard JA; Sliskovic DR; Roth BD; Stanfield RL; Hamelehle KL; Bousley RF; Krause BR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):289-94. PubMed ID: 9871672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. alpha-Substituted malonester amides: tools to define the relationship between ACAT inhibition and adrenal toxicity.
    Sliskovic DR; Picard JA; O'Brien PM; Liao P; Roark WH; Roth BD; Anderson MA; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Homan R; Reindel JF; Stanfield RL; Turluck D; Krause BR
    J Med Chem; 1998 Feb; 41(5):682-90. PubMed ID: 9513596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT).
    Matsuyama N; Kosaka T; Fukuhara M; Soda Y; Mizuno K
    Bioorg Med Chem Lett; 1999 Jul; 9(14):2039-42. PubMed ID: 10450977
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides.
    Kataoka K; Shiota T; Takeyasu T; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
    J Med Chem; 1995 Aug; 38(16):3174-86. PubMed ID: 7636880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of acyl-CoA: cholesterol acyltransferase. II. Preparation and hypocholesterolemic activity of optically active dibenz[b,e]oxepin-11-carboxanilides.
    Kumazawa T; Yanase M; Shirakura S; Ohishi E; Yamada K; Matsumiya S; Kono M
    Chem Pharm Bull (Tokyo); 1996 Jan; 44(1):222-5. PubMed ID: 8582041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of acyl-Coa:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents.
    Trivedi BK; Holmes A; Stoeber TL; Blankley CJ; Roark WH; Picard JA; Shaw MK; Essenburg AD; Stanfield RL; Krause BR
    J Med Chem; 1993 Oct; 36(22):3300-7. PubMed ID: 8230120
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of acyl-CoA:cholesterol acyltransferase: novel trisubstituted ureas as hypocholesterolemic agents.
    Purchase TS; Essenburg AD; Hamelehle KL; Hes MS; Holmes A; Krause BR; Stanfield RL; Trivedi BK
    Bioorg Med Chem; 1997 Apr; 5(4):739-47. PubMed ID: 9158873
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ACAT-selective and nonselective DGAT1 inhibition: adrenocortical effects--a cross-species comparison.
    Floettmann JE; Buckett LK; Turnbull AV; Smith T; Hallberg C; Birch A; Lees D; Jones HB
    Toxicol Pathol; 2013; 41(7):941-50. PubMed ID: 23427273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.