422 related articles for article (PubMed ID: 22044028)
1. The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
Cáliz R; del Amo J; Balsa A; Blanco F; Silva L; Sanmarti R; Martínez FG; Collado MD; Ramirez Mdel C; Tejedor D; Artieda M; Pascual-Salcedo D; Oreiro N; Andreu JL; Graell E; Simon L; Martínez A; Mulero J
Scand J Rheumatol; 2012 Feb; 41(1):10-4. PubMed ID: 22044028
[TBL] [Abstract][Full Text] [Related]
2. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
Wessels JA; de Vries-Bouwstra JK; Heijmans BT; Slagboom PE; Goekoop-Ruiterman YP; Allaart CF; Kerstens PJ; van Zeben D; Breedveld FC; Dijkmans BA; Huizinga TW; Guchelaar HJ
Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
[TBL] [Abstract][Full Text] [Related]
3. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
Berkun Y; Levartovsky D; Rubinow A; Orbach H; Aamar S; Grenader T; Abou Atta I; Mevorach D; Friedman G; Ben-Yehuda A
Ann Rheum Dis; 2004 Oct; 63(10):1227-31. PubMed ID: 15361376
[TBL] [Abstract][Full Text] [Related]
4. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
Kumagai K; Hiyama K; Oyama T; Maeda H; Kohno N
Int J Mol Med; 2003 May; 11(5):593-600. PubMed ID: 12684695
[TBL] [Abstract][Full Text] [Related]
5. Methylene tetrahydrofolate reductase genotypes frequencies: association with toxicity and response to methotrexate in rheumatoid arthritis patients.
Saleh MM; Irshaid YM; Mustafa KN
Int J Clin Pharmacol Ther; 2015 Feb; 53(2):154-62. PubMed ID: 25492850
[TBL] [Abstract][Full Text] [Related]
6. Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
Kim SK; Jun JB; El-Sohemy A; Bae SC
J Rheumatol; 2006 Jul; 33(7):1266-74. PubMed ID: 16758511
[TBL] [Abstract][Full Text] [Related]
7. Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
Taniguchi A; Urano W; Tanaka E; Furihata S; Kamitsuji S; Inoue E; Yamanaka M; Yamanaka H; Kamatani N
Pharmacogenet Genomics; 2007 Jun; 17(6):383-90. PubMed ID: 17502830
[TBL] [Abstract][Full Text] [Related]
8. Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.
Aggarwal P; Naik S; Mishra KP; Aggarwal A; Misra R
Indian J Med Res; 2006 Nov; 124(5):521-6. PubMed ID: 17213520
[TBL] [Abstract][Full Text] [Related]
9. MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.
Owen SA; Lunt M; Bowes J; Hider SL; Bruce IN; Thomson W; Barton A
Pharmacogenomics J; 2013 Apr; 13(2):137-47. PubMed ID: 21931346
[TBL] [Abstract][Full Text] [Related]
10. Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
Chaabane S; Marzouk S; Akrout R; Ben Hamad M; Achour Y; Rebai A; Keskes L; Fourati H; Bahloul Z; Maalej A
Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):385-93. PubMed ID: 26077125
[TBL] [Abstract][Full Text] [Related]
11. Influence of MTHFR C677T polymorphism on methotrexate monotherapy discontinuation in rheumatoid arthritis patients: results from the GAPAID European project.
Uribarri M; Ruiz-Larrañaga O; Arteta D; Hernández L; Alcaro MC; Martínez A; Escorza-Treviño S; Estonba A; Migliorini P; Czirják L; del Amo J
Clin Exp Rheumatol; 2015; 33(5):699-705. PubMed ID: 26314492
[TBL] [Abstract][Full Text] [Related]
12. Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.
Mena JP; Salazar-Páramo M; González-López L; Gámez-Nava JI; Sandoval-Ramirez L; Sánchez JD; Figuera LE; Muñoz-Valle FJ; Vazquez del Mercado M; Dávalos IP
Pharmacogenomics J; 2011 Aug; 11(4):287-91. PubMed ID: 20514079
[TBL] [Abstract][Full Text] [Related]
13. Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
Plaza-Plaza JC; Aguilera M; Cañadas-Garre M; Chemello C; González-Utrilla A; Faus Dader MJ; Calleja MA
OMICS; 2012 Nov; 16(11):589-95. PubMed ID: 23095111
[TBL] [Abstract][Full Text] [Related]
14. Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
Schmeling H; Biber D; Heins S; Horneff G
J Rheumatol; 2005 Sep; 32(9):1832-6. PubMed ID: 16142884
[TBL] [Abstract][Full Text] [Related]
15. The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
Soukup T; Dosedel M; Pavek P; Nekvindova J; Barvik I; Bubancova I; Bradna P; Kubena AA; Carazo AF; Veleta T; Vlcek J
Rheumatol Int; 2015 Jul; 35(7):1149-61. PubMed ID: 25618758
[TBL] [Abstract][Full Text] [Related]
16. Methylenetetrahydrofolate reductase polymorphisms, C677T and A1298C, are associated with methotrexate-related toxicities in Korean patients with rheumatoid arthritis.
Choe JY; Lee H; Jung HY; Park SH; Bae SC; Kim SK
Rheumatol Int; 2012 Jun; 32(6):1837-42. PubMed ID: 21773884
[TBL] [Abstract][Full Text] [Related]
17. 2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis.
Berkun Y; Abou Atta I; Rubinow A; Orbach H; Levartovsky D; Aamar S; Arbel O; Dresner-Pollak R; Friedman G; Ben-Yehuda A
J Rheumatol; 2007 Aug; 34(8):1664-9. PubMed ID: 17611986
[TBL] [Abstract][Full Text] [Related]
18. Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Urano W; Taniguchi A; Yamanaka H; Tanaka E; Nakajima H; Matsuda Y; Akama H; Kitamura Y; Kamatani N
Pharmacogenetics; 2002 Apr; 12(3):183-90. PubMed ID: 11927833
[TBL] [Abstract][Full Text] [Related]
19. Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
Taraborelli M; Andreoli L; Archetti S; Ferrari M; Cattaneo R; Tincani A
Clin Exp Rheumatol; 2009; 27(3):499-502. PubMed ID: 19604445
[TBL] [Abstract][Full Text] [Related]
20. Lack of association between MTHFR A1298C polymorphism and outcome of methotrexate treatment in rheumatoid arthritis patients: evidence from a systematic review and meta-analysis.
Fan H; Li Y; Zhang L; Li Y; Li W
Int J Rheum Dis; 2017 May; 20(5):526-540. PubMed ID: 28544525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
