143 related articles for article (PubMed ID: 22045383)
1. A concise route to the macrocyclic core of the rakicidins.
Poulsen TB
Chem Commun (Camb); 2011 Dec; 47(48):12837-9. PubMed ID: 22045383
[TBL] [Abstract][Full Text] [Related]
2. The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile--development of a general synthetic strategy.
Clement LL; Tsakos M; Schaffert ES; Scavenius C; Enghild JJ; Poulsen TB
Chem Commun (Camb); 2015 Aug; 51(62):12427-30. PubMed ID: 26146360
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors.
Yasuda Y; Arakawa T; Nawata Y; Shimada S; Oishi S; Fujii N; Nishimura S; Hattori A; Kakeya H
Bioorg Med Chem; 2015 Apr; 23(8):1776-87. PubMed ID: 25773014
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of ent-BE-43547A
Villadsen NL; Jacobsen KM; Keiding UB; Weibel ET; Christiansen B; Vosegaard T; Bjerring M; Jensen F; Johannsen M; Tørring T; Poulsen TB
Nat Chem; 2017 Mar; 9(3):264-272. PubMed ID: 28221346
[TBL] [Abstract][Full Text] [Related]
5. Rakicidins, new cytotoxic lipopeptides from Micromonospora sp. fermentation, isolation and characterization.
McBrien KD; Berry RL; Lowe SE; Neddermann KM; Bursuker I; Huang S; Klohr SE; Leet JE
J Antibiot (Tokyo); 1995 Dec; 48(12):1446-52. PubMed ID: 8557602
[TBL] [Abstract][Full Text] [Related]
6. Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α.
Shimizu T; Takahashi N; Huber VJ; Asawa Y; Ueda H; Yoshimori A; Muramatsu Y; Seimiya H; Kouji H; Nakamura H; Oguri H
Bioorg Med Chem; 2021 Jan; 30():115949. PubMed ID: 33360196
[TBL] [Abstract][Full Text] [Related]
7. Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase.
Szałaj N; Lu L; Benediktsdottir A; Zamaratski E; Cao S; Olanders G; Hedgecock C; Karlén A; Erdélyi M; Hughes D; Mowbray SL; Brandt P
Eur J Med Chem; 2018 Sep; 157():1346-1360. PubMed ID: 30196059
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway.
Mooring SR; Jin H; Devi NS; Jabbar AA; Kaluz S; Liu Y; Van Meir EG; Wang B
J Med Chem; 2011 Dec; 54(24):8471-89. PubMed ID: 22032632
[TBL] [Abstract][Full Text] [Related]
9. Two new rakicidin derivatives from marine
Chen L; Xie L; Zhao W; Zhou J; Jiang H; Liu W; Jiang H; Lin F
Nat Prod Res; 2024 Apr; 38(8):1354-1361. PubMed ID: 36352349
[TBL] [Abstract][Full Text] [Related]
10. Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.
Burroughs SK; Kaluz S; Wang D; Wang K; Van Meir EG; Wang B
Future Med Chem; 2013 Apr; 5(5):553-72. PubMed ID: 23573973
[TBL] [Abstract][Full Text] [Related]
11. Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.
Sang F; Ding Y; Wang J; Sun B; Sun J; Geng Y; Zhang Z; Ding K; Wu LL; Liu JW; Bai C; Yang G; Zhang Q; Li LY; Chen Y
J Med Chem; 2016 Feb; 59(3):1184-96. PubMed ID: 26814890
[TBL] [Abstract][Full Text] [Related]
12. Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045.
Luo S; Kang HS; Krunic A; Chen WL; Yang J; Woodard JL; Fuchs JR; Hyun Cho S; Franzblau SG; Swanson SM; Orjala J
Bioorg Med Chem; 2015 Jul; 23(13):3153-62. PubMed ID: 26001342
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible factor-1 (HIF-1) inhibitors.
Li G; Dong H; Ma Y; Shao K; Li Y; Wu X; Wang S; Shao Y; Zhao W
Bioorg Med Chem Lett; 2019 Aug; 29(16):2327-2331. PubMed ID: 31281016
[TBL] [Abstract][Full Text] [Related]
14. Syntheses and anti-pancreatic cancer activities of rakicidin A analogues.
Chen J; Li J; Wu L; Geng Y; Yu J; Chong C; Wang M; Gao Y; Bai C; Ding Y; Chen Y; Zhang Q
Eur J Med Chem; 2018 May; 151():601-627. PubMed ID: 29656202
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis of a novel 4-O-methylsaucerneol analogue LXY7824 as potent HIF-1 inhibitor and anti-cancer agent.
Liu XY; Li XY; Yang FL; Li Y; Jiao XZ; Xie P
J Asian Nat Prod Res; 2018 Jun; 20(6):545-558. PubMed ID: 29862843
[TBL] [Abstract][Full Text] [Related]
16. Building upon Nature's Framework: Overview of Key Strategies Toward Increasing Drug-Like Properties of Natural Product Cyclopeptides and Macrocycles.
Blanco MJ
Methods Mol Biol; 2019; 2001():203-233. PubMed ID: 31134573
[TBL] [Abstract][Full Text] [Related]
17. Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors.
Cheng-Sánchez I; Carrillo P; Sánchez-Ruiz A; Martínez-Poveda B; Quesada AR; Medina MA; López-Romero JM; Sarabia F
J Org Chem; 2018 May; 83(10):5365-5383. PubMed ID: 29676156
[TBL] [Abstract][Full Text] [Related]
18. Strongylophorines: natural product inhibitors of hypoxia-inducible factor-1 transcriptional pathway.
Mohammed KA; Jadulco RC; Bugni TS; Harper MK; Sturdy M; Ireland CM
J Med Chem; 2008 Mar; 51(5):1402-5. PubMed ID: 18278856
[TBL] [Abstract][Full Text] [Related]
19. A multicomponent macrocyclization strategy to natural product-like cyclic lipopeptides: synthesis and anticancer evaluation of surfactin and mycosubtilin analogues.
Morejón MC; Laub A; Kaluđerović GN; Puentes AR; Hmedat AN; Otero-González AJ; Rivera DG; Wessjohann LA
Org Biomol Chem; 2017 May; 15(17):3628-3637. PubMed ID: 28406518
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, hypoxia-selective cytotoxicity of new 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives.
Xia Q; Zhang L; Zhang J; Sheng R; Yang B; He Q; Hu Y
Eur J Med Chem; 2011 Mar; 46(3):919-26. PubMed ID: 21281992
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]