These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 22048127)

  • 1. Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.
    Meng XM; Huang XR; Xiao J; Chung AC; Qin W; Chen HY; Lan HY
    Kidney Int; 2012 Feb; 81(3):266-79. PubMed ID: 22048127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro.
    Meng XM; Huang XR; Xiao J; Chen HY; Zhong X; Chung AC; Lan HY
    J Pathol; 2012 Jun; 227(2):175-88. PubMed ID: 22190171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smad3 mediates ANG II-induced hypertensive kidney disease in mice.
    Liu Z; Huang XR; Lan HY
    Am J Physiol Renal Physiol; 2012 Apr; 302(8):F986-97. PubMed ID: 22237801
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy.
    Liu Z; Huang XR; Chen HY; Penninger JM; Lan HY
    Lab Invest; 2012 May; 92(5):650-61. PubMed ID: 22330342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.
    Chung AC; Huang XR; Zhou L; Heuchel R; Lai KN; Lan HY
    Nephrol Dial Transplant; 2009 May; 24(5):1443-54. PubMed ID: 19096081
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced Smad3 protein expression and altered transforming growth factor-beta1-mediated signaling in cystic fibrosis epithelial cells.
    Kelley TJ; Elmer HL; Corey DA
    Am J Respir Cell Mol Biol; 2001 Dec; 25(6):732-8. PubMed ID: 11726399
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.
    Wang W; Huang XR; Li AG; Liu F; Li JH; Truong LD; Wang XJ; Lan HY
    J Am Soc Nephrol; 2005 May; 16(5):1371-83. PubMed ID: 15788474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation.
    Liu Z; Huang XR; Chen HY; Fung E; Liu J; Lan HY
    Hypertension; 2017 Oct; 70(4):822-830. PubMed ID: 28808068
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells.
    Grau AM; Datta PK; Zi J; Halder SK; Beauchamp RD
    Cell Signal; 2006 Jul; 18(7):1041-50. PubMed ID: 16288847
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Augmented cytoplasmic Smad4 induces acceleration of TGF-beta1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation.
    Goto Y; Manabe N; Uchio-Yamada K; Yamaguchi-Yamada M; Inoue N; Yamamoto Y; Ogura A; Nagano N; Miyamoto H
    Cell Tissue Res; 2004 Feb; 315(2):209-21. PubMed ID: 14615933
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB.
    Nagarajan RP; Chen F; Li W; Vig E; Harrington MA; Nakshatri H; Chen Y
    Biochem J; 2000 Jun; 348 Pt 3(Pt 3):591-6. PubMed ID: 10839991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Diverse roles of TGF-β/Smads in renal fibrosis and inflammation.
    Lan HY
    Int J Biol Sci; 2011; 7(7):1056-67. PubMed ID: 21927575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
    Heeg MH; Koziolek MJ; Vasko R; Schaefer L; Sharma K; Müller GA; Strutz F
    Kidney Int; 2005 Jul; 68(1):96-109. PubMed ID: 15954899
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.
    Liu GX; Li YQ; Huang XR; Wei L; Chen HY; Shi YJ; Heuchel RL; Lan HY
    PLoS One; 2013; 8(1):e53573. PubMed ID: 23301086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling.
    You YK; Luo Q; Wu WF; Zhang JJ; Zhu HJ; Lao L; Lan HY; Chen HY; Cheng YX
    J Cell Mol Med; 2019 Aug; 23(8):5576-5587. PubMed ID: 31211499
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells.
    Huo YY; Hu YC; He XR; Wang Y; Song BQ; Zhou PK; Zhu MX; Li G; Wu DC
    Cell Biol Toxicol; 2007 Mar; 23(2):113-28. PubMed ID: 17096210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment.
    Chen L; Yang T; Lu DW; Zhao H; Feng YL; Chen H; Chen DQ; Vaziri ND; Zhao YY
    Biomed Pharmacother; 2018 May; 101():670-681. PubMed ID: 29518614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.
    Meng XM; Huang XR; Chung AC; Qin W; Shao X; Igarashi P; Ju W; Bottinger EP; Lan HY
    J Am Soc Nephrol; 2010 Sep; 21(9):1477-87. PubMed ID: 20595680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxymatrine inhibits renal fibrosis of obstructive nephropathy by downregulating the TGF-β1-Smad3 pathway.
    Wang HW; Shi L; Xu YP; Qin XY; Wang QZ
    Ren Fail; 2016 Jul; 38(6):945-51. PubMed ID: 27050799
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-β/Smad signaling pathway.
    Dou F; Ding Y; Wang C; Duan J; Wang W; Xu H; Zhao X; Wang J; Wen A
    Biochem Pharmacol; 2020 Oct; 180():114079. PubMed ID: 32511988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.