These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 22050682)

  • 1. Review of synthesis, biological assay and QSAR studies of β-secretase inhibitors.
    Niño H; García-Pintos I; Rodríguez-Borges JE; Escobar-Cubiella M; García-Mera X; Prado-Prado F
    Curr Comput Aided Drug Des; 2011 Dec; 7(4):263-75. PubMed ID: 22050682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Review of synthesis, assay, and prediction of β and γ-secretase inhibitors.
    Niño H; Rodríguez-Borges JE; García-Mera X; Prado-Prado F
    Curr Top Med Chem; 2012; 12(8):828-44. PubMed ID: 22352911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with beta-secretase.
    Zuo Z; Luo X; Zhu W; Shen J; Shen X; Jiang H; Chen K
    Bioorg Med Chem; 2005 Mar; 13(6):2121-31. PubMed ID: 15727865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inkjet printing-based β-secretase fluorescence resonance energy transfer (FRET) assay for screening of potential β-secretase inhibitors of Alzheimer's disease.
    Lee J; Samson AAS; Song JM
    Anal Chim Acta; 2018 Aug; 1022():89-95. PubMed ID: 29729742
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Alzheimer's disease beta-secretase enzyme, BACE1.
    Cole SL; Vassar R
    Mol Neurodegener; 2007 Nov; 2():22. PubMed ID: 18005427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comprehensive 3D-QSAR and binding mode of BACE-1 inhibitors using R-group search and molecular docking.
    Huang D; Liu Y; Shi B; Li Y; Wang G; Liang G
    J Mol Graph Model; 2013 Sep; 45():65-83. PubMed ID: 24004830
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches.
    Tran TS; Le MT; Tran TD; Tran TH; Thai KM
    Molecules; 2020 Aug; 25(16):. PubMed ID: 32785161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
    Roberds SL; Anderson J; Basi G; Bienkowski MJ; Branstetter DG; Chen KS; Freedman SB; Frigon NL; Games D; Hu K; Johnson-Wood K; Kappenman KE; Kawabe TT; Kola I; Kuehn R; Lee M; Liu W; Motter R; Nichols NF; Power M; Robertson DW; Schenk D; Schoor M; Shopp GM; Shuck ME; Sinha S; Svensson KA; Tatsuno G; Tintrup H; Wijsman J; Wright S; McConlogue L
    Hum Mol Genet; 2001 Jun; 10(12):1317-24. PubMed ID: 11406613
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.
    Gay M; Evrard C; Descamps F; Carato P; Renault N; Coevoet M; Eddarkaoui S; Baud C; Larchanché PE; Buée L; El Bakali J; Vingtdeux V; Sergeant N; Melnyk P
    Eur J Med Chem; 2018 Nov; 159():104-125. PubMed ID: 30268822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Review of theoretical studies for prediction of neurodegenerative inhibitors.
    Prado-Prado F; García I
    Mini Rev Med Chem; 2012 Jun; 12(6):452-66. PubMed ID: 22587762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2D QSAR studies on series of human beta-secretase (BACE-1) inhibitors.
    Cruz DS; Castilho MS
    Med Chem; 2014 Mar; 10(2):162-73. PubMed ID: 23627297
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemometric design to explore pharmacophore features of BACE inhibitors for controlling Alzheimer's disease.
    Hossain T; Mukherjee A; Saha A
    Mol Biosyst; 2015 Feb; 11(2):549-57. PubMed ID: 25435329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study on the active mechanism of β-secretase inhibitors by molecular simulations.
    Tian YL; Lv M; Li JJ; Xu T; Zhai HL; Zhang XY
    Eur J Pharm Sci; 2015 Aug; 76():138-48. PubMed ID: 25965961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacophore based 3D-QSAR modeling, virtual screening and docking for identification of potential inhibitors of β-secretase.
    Palakurti R; Vadrevu R
    Comput Biol Chem; 2017 Jun; 68():107-117. PubMed ID: 28288354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BACE inhibition-dependent repair of Alzheimer's pathophysiology.
    Keskin AD; Kekuš M; Adelsberger H; Neumann U; Shimshek DR; Song B; Zott B; Peng T; Förstl H; Staufenbiel M; Nelken I; Sakmann B; Konnerth A; Busche MA
    Proc Natl Acad Sci U S A; 2017 Aug; 114(32):8631-8636. PubMed ID: 28739891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular Docking and 3D Qsar Studies of C000000956 as a Potent Inhibitor of Bace-1.
    Joseph OA; Babatomiwa K; Niyi A; Olaposi O; Olumide I
    Drug Res (Stuttg); 2019 Aug; 69(8):451-457. PubMed ID: 30780168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent beta-secretase inhibitory leads.
    Al-Nadaf A; Abu Sheikha G; Taha MO
    Bioorg Med Chem; 2010 May; 18(9):3088-115. PubMed ID: 20378363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Secretase inhibitors and modulators for Alzheimer's disease treatment.
    Tomita T
    Expert Rev Neurother; 2009 May; 9(5):661-79. PubMed ID: 19402777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead.
    Kumar D; Ganeshpurkar A; Kumar D; Modi G; Gupta SK; Singh SK
    Eur J Med Chem; 2018 Mar; 148():436-452. PubMed ID: 29477076
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simple structure-based approach for predicting the activity of inhibitors of beta-secretase (BACE1) associated with Alzheimer's disease.
    Nastase AF; Boyd DB
    J Chem Inf Model; 2012 Dec; 52(12):3302-7. PubMed ID: 23198745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.