857 related articles for article (PubMed ID: 22052977)
1. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
Anastasiou D; Poulogiannis G; Asara JM; Boxer MB; Jiang JK; Shen M; Bellinger G; Sasaki AT; Locasale JW; Auld DS; Thomas CJ; Vander Heiden MG; Cantley LC
Science; 2011 Dec; 334(6060):1278-83. PubMed ID: 22052977
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension.
Guo D; Gu J; Jiang H; Ahmed A; Zhang Z; Gu Y
J Mol Cell Cardiol; 2016 Feb; 91():179-87. PubMed ID: 26774701
[TBL] [Abstract][Full Text] [Related]
3. Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveal the effects of multiple oxidation on cellular oxidative stress response.
Irokawa H; Numasaki S; Kato S; Iwai K; Inose-Maruyama A; Ohdate T; Hwang GW; Toyama T; Watanabe T; Kuge S
Biochem J; 2021 Apr; 478(7):1453-1470. PubMed ID: 33749780
[TBL] [Abstract][Full Text] [Related]
4. OSU-A9 induced-reactive oxygen species cause cytotoxicity in duodenal and gastric cancer cells by decreasing phosphorylated nuclear pyruvate kinase M2 protein levels.
Chiu CF; Weng JR; Lee SL; Wu CY; Chu PC; Shan YS; Yang HR; Bai LY
Biochem Pharmacol; 2020 Apr; 174():113811. PubMed ID: 31954719
[TBL] [Abstract][Full Text] [Related]
5. Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth.
Xiangyun Y; Xiaomin N; Linping G; Yunhua X; Ziming L; Yongfeng Y; Zhiwei C; Shun L
Oncotarget; 2017 Jan; 8(4):6984-6993. PubMed ID: 28036303
[TBL] [Abstract][Full Text] [Related]
6. Immunoglobulin Superfamily Containing Leucine-Rich Repeat (ISLR) Serves as a Redox Sensor That Modulates Antioxidant Capacity by Suppressing Pyruvate Kinase Isozyme M2 Activity.
Wang T; Chen M; Su Y; Zhang Y; Liu C; Lan M; Li L; Liu F; Li N; Yu Y; Xiong L; Wang K; Liu J; Xu Q; Hu Y; Jia Y; Cao Y; Pan J; Meng Q
Cells; 2024 May; 13(10):. PubMed ID: 38786060
[TBL] [Abstract][Full Text] [Related]
7. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
Hitosugi T; Kang S; Vander Heiden MG; Chung TW; Elf S; Lythgoe K; Dong S; Lonial S; Wang X; Chen GZ; Xie J; Gu TL; Polakiewicz RD; Roesel JL; Boggon TJ; Khuri FR; Gilliland DG; Cantley LC; Kaufman J; Chen J
Sci Signal; 2009 Nov; 2(97):ra73. PubMed ID: 19920251
[TBL] [Abstract][Full Text] [Related]
8. Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
Iqbal MA; Siddiqui FA; Gupta V; Chattopadhyay S; Gopinath P; Kumar B; Manvati S; Chaman N; Bamezai RN
Mol Cancer; 2013 Jul; 12():72. PubMed ID: 23837608
[TBL] [Abstract][Full Text] [Related]
9. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Anastasiou D; Yu Y; Israelsen WJ; Jiang JK; Boxer MB; Hong BS; Tempel W; Dimov S; Shen M; Jha A; Yang H; Mattaini KR; Metallo CM; Fiske BP; Courtney KD; Malstrom S; Khan TM; Kung C; Skoumbourdis AP; Veith H; Southall N; Walsh MJ; Brimacombe KR; Leister W; Lunt SY; Johnson ZR; Yen KE; Kunii K; Davidson SM; Christofk HR; Austin CP; Inglese J; Harris MH; Asara JM; Stephanopoulos G; Salituro FG; Jin S; Dang L; Auld DS; Park HW; Cantley LC; Thomas CJ; Vander Heiden MG
Nat Chem Biol; 2012 Oct; 8(10):839-47. PubMed ID: 22922757
[TBL] [Abstract][Full Text] [Related]
10. Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells.
Tamada M; Nagano O; Tateyama S; Ohmura M; Yae T; Ishimoto T; Sugihara E; Onishi N; Yamamoto T; Yanagawa H; Suematsu M; Saya H
Cancer Res; 2012 Mar; 72(6):1438-48. PubMed ID: 22293754
[TBL] [Abstract][Full Text] [Related]
11. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
Masaki S; Hashimoto K; Kihara D; Tsuzuki C; Kataoka N; Suzuki K
Biochem Biophys Res Commun; 2020 Jun; 526(4):973-977. PubMed ID: 32295714
[TBL] [Abstract][Full Text] [Related]
12. Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.
Siragusa M; Thöle J; Bibli SI; Luck B; Loot AE; de Silva K; Wittig I; Heidler J; Stingl H; Randriamboavonjy V; Kohlstedt K; Brüne B; Weigert A; Fisslthaler B; Fleming I
EMBO J; 2019 Sep; 38(17):e100938. PubMed ID: 31328803
[TBL] [Abstract][Full Text] [Related]
13. Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress.
Qi H; Ning X; Yu C; Ji X; Jin Y; McNutt MA; Yin Y
Cell Death Dis; 2019 Feb; 10(3):170. PubMed ID: 30787272
[TBL] [Abstract][Full Text] [Related]
14. Insulin regulates glucose consumption and lactate production through reactive oxygen species and pyruvate kinase M2.
Li Q; Liu X; Yin Y; Zheng JT; Jiang CF; Wang J; Shen H; Li CY; Wang M; Liu LZ; Jiang BH
Oxid Med Cell Longev; 2014; 2014():504953. PubMed ID: 24895527
[TBL] [Abstract][Full Text] [Related]
15. Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Chaneton B; Hillmann P; Zheng L; Martin ACL; Maddocks ODK; Chokkathukalam A; Coyle JE; Jankevics A; Holding FP; Vousden KH; Frezza C; O'Reilly M; Gottlieb E
Nature; 2012 Nov; 491(7424):458-462. PubMed ID: 23064226
[TBL] [Abstract][Full Text] [Related]
16. Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread.
Giannoni E; Taddei ML; Morandi A; Comito G; Calvani M; Bianchini F; Richichi B; Raugei G; Wong N; Tang D; Chiarugi P
Oncotarget; 2015 Sep; 6(27):24061-74. PubMed ID: 26183399
[TBL] [Abstract][Full Text] [Related]
17. PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells.
Yu Z; Huang L; Qiao P; Jiang A; Wang L; Yang T; Tang S; Zhang W; Ren C
Biochem Biophys Res Commun; 2016 May; 473(4):953-958. PubMed ID: 27045080
[TBL] [Abstract][Full Text] [Related]
18. 2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2.
Yoon YJ; Kim YH; Jin Y; Chi SW; Moon JH; Han DC; Kwon BM
Cancer Lett; 2018 Oct; 434():42-55. PubMed ID: 30009856
[TBL] [Abstract][Full Text] [Related]
19. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
Toller-Kawahisa JE; Hiroki CH; Silva CMS; Nascimento DC; Públio GA; Martins TV; Damasceno LEA; Veras FP; Viacava PR; Sukesada FY; Day EA; Zotta A; Ryan TAJ; Moreira da Silva R; Cunha TM; Lopes NP; Cunha FQ; O'Neill LAJ; Alves-Filho JC
Nat Commun; 2023 Jul; 14(1):4280. PubMed ID: 37460614
[TBL] [Abstract][Full Text] [Related]
20.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Next] [New Search]
