BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 22053191)

  • 1. FGF/FGFR signaling coordinates skull development by modulating magnitude of morphological integration: evidence from Apert syndrome mouse models.
    Martínez-Abadías N; Heuzé Y; Wang Y; Jabs EW; Aldridge K; Richtsmeier JT
    PLoS One; 2011; 6(10):e26425. PubMed ID: 22053191
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.
    Wang Y; Sun M; Uhlhorn VL; Zhou X; Peter I; Martinez-Abadias N; Hill CA; Percival CJ; Richtsmeier JT; Huso DL; Jabs EW
    BMC Dev Biol; 2010 Feb; 10():22. PubMed ID: 20175913
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome.
    Luo F; Xie Y; Xu W; Huang J; Zhou S; Wang Z; Luo X; Liu M; Chen L; Du X
    Int J Biol Sci; 2017; 13(1):32-45. PubMed ID: 28123344
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
    Yin L; Du X; Li C; Xu X; Chen Z; Su N; Zhao L; Qi H; Li F; Xue J; Yang J; Jin M; Deng C; Chen L
    Bone; 2008 Apr; 42(4):631-43. PubMed ID: 18242159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Processes and patterns: Insights on cranial covariation from an Apert syndrome mouse model.
    Singh N; Heuzé Y; Holmes G
    Dev Dyn; 2022 Oct; 251(10):1684-1697. PubMed ID: 35582939
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beyond the closed suture in apert syndrome mouse models: evidence of primary effects of FGFR2 signaling on facial shape at birth.
    Martínez-Abadías N; Percival C; Aldridge K; Hill CA; Ryan T; Sirivunnabood S; Wang Y; Jabs EW; Richtsmeier JT
    Dev Dyn; 2010 Nov; 239(11):3058-71. PubMed ID: 20842696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Postnatal brain and skull growth in an Apert syndrome mouse model.
    Hill CA; Martínez-Abadías N; Motch SM; Austin JR; Wang Y; Jabs EW; Richtsmeier JT; Aldridge K
    Am J Med Genet A; 2013 Apr; 161A(4):745-57. PubMed ID: 23495236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice.
    Shin HR; Kim BS; Kim HJ; Yoon H; Kim WJ; Choi JY; Ryoo HM
    J Cell Physiol; 2022 Apr; 237(4):2155-2168. PubMed ID: 35048384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamic morphological changes in the skulls of mice mimicking human Apert syndrome resulting from gain-of-function mutation of FGFR2 (P253R).
    Du X; Weng T; Sun Q; Su N; Chen Z; Qi H; Jin M; Yin L; He Q; Chen L
    J Anat; 2010 Aug; 217(2):97-105. PubMed ID: 20557404
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Craniofacial divergence by distinct prenatal growth patterns in Fgfr2 mutant mice.
    Motch Perrine SM; Cole TM; Martínez-Abadías N; Aldridge K; Jabs EW; Richtsmeier JT
    BMC Dev Biol; 2014 Feb; 14():8. PubMed ID: 24580805
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apert syndrome mutant FGFR2 and its soluble form reciprocally alter osteogenesis of primary calvarial osteoblasts.
    Suzuki H; Suda N; Shiga M; Kobayashi Y; Nakamura M; Iseki S; Moriyama K
    J Cell Physiol; 2012 Sep; 227(9):3267-77. PubMed ID: 22105374
    [TBL] [Abstract][Full Text] [Related]  

  • 12. From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.
    Martínez-Abadías N; Holmes G; Pankratz T; Wang Y; Zhou X; Jabs EW; Richtsmeier JT
    Dis Model Mech; 2013 May; 6(3):768-79. PubMed ID: 23519026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Negative autoregulation of fibroblast growth factor receptor 2 expression characterizing cranial development in cases of Apert (P253R mutation) and Pfeiffer (C278F mutation) syndromes and suggesting a basis for differences in their cranial phenotypes.
    Britto JA; Moore RL; Evans RD; Hayward RD; Jones BM
    J Neurosurg; 2001 Oct; 95(4):660-73. PubMed ID: 11596961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The study of abnormal bone development in the Apert syndrome Fgfr2+/S252W mouse using a 3D hydrogel culture model.
    Yang F; Wang Y; Zhang Z; Hsu B; Jabs EW; Elisseeff JH
    Bone; 2008 Jul; 43(1):55-63. PubMed ID: 18407821
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of FGFR Signaling on Cell Proliferation and Differentiation of Apert Dental Cells.
    Lu C; Huguley S; Cui C; Cabaniss LB; Waite PD; Sarver DM; Mamaeva OA; MacDougall M
    Cells Tissues Organs; 2016; 201(1):26-37. PubMed ID: 26613250
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model.
    Morita J; Nakamura M; Kobayashi Y; Deng CX; Funato N; Moriyama K
    Dev Dyn; 2014 Apr; 243(4):560-7. PubMed ID: 24259495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation.
    Chen P; Zhang L; Weng T; Zhang S; Sun S; Chang M; Li Y; Zhang B; Zhang L
    PLoS One; 2014; 9(1):e87311. PubMed ID: 24489893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition or activation of Apert syndrome FGFR2 (S252W) signaling by specific glycosaminoglycans.
    McDowell LM; Frazier BA; Studelska DR; Giljum K; Chen J; Liu J; Yu K; Ornitz DM; Zhang L
    J Biol Chem; 2006 Mar; 281(11):6924-30. PubMed ID: 16373332
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome.
    Yeh E; Fanganiello RD; Sunaga DY; Zhou X; Holmes G; Rocha KM; Alonso N; Matushita H; Wang Y; Jabs EW; Passos-Bueno MR
    PLoS One; 2013; 8(4):e60439. PubMed ID: 23593218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Septal chondrocyte hypertrophy contributes to midface deformity in a mouse model of Apert syndrome.
    Kim BS; Shin HR; Kim HJ; Yoon H; Cho YD; Choi KY; Choi JY; Kim WJ; Ryoo HM
    Sci Rep; 2021 Apr; 11(1):7979. PubMed ID: 33846505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.