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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

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    Mavaddat N; Barrowdale D; Andrulis IL; Domchek SM; Eccles D; Nevanlinna H; Ramus SJ; Spurdle A; Robson M; Sherman M; Mulligan AM; Couch FJ; Engel C; McGuffog L; Healey S; Sinilnikova OM; Southey MC; Terry MB; Goldgar D; O'Malley F; John EM; Janavicius R; Tihomirova L; Hansen TV; Nielsen FC; Osorio A; Stavropoulou A; Benítez J; Manoukian S; Peissel B; Barile M; Volorio S; Pasini B; Dolcetti R; Putignano AL; Ottini L; Radice P; Hamann U; Rashid MU; Hogervorst FB; Kriege M; van der Luijt RB; ; Peock S; Frost D; Evans DG; Brewer C; Walker L; Rogers MT; Side LE; Houghton C; ; Weaver J; Godwin AK; Schmutzler RK; Wappenschmidt B; Meindl A; Kast K; Arnold N; Niederacher D; Sutter C; Deissler H; Gadzicki D; Preisler-Adams S; Varon-Mateeva R; Schönbuchner I; Gevensleben H; Stoppa-Lyonnet D; Belotti M; Barjhoux L; ; Isaacs C; Peshkin BN; Caldes T; de la Hoya M; Cañadas C; Heikkinen T; Heikkilä P; Aittomäki K; Blanco I; Lazaro C; Brunet J; Agnarsson BA; Arason A; Barkardottir RB; Dumont M; Simard J; Montagna M; Agata S; D'Andrea E; Yan M; Fox S; ; Rebbeck TR; Rubinstein W; Tung N; Garber JE; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Szabo C; Offit K; Sakr R; Gaudet MM; Singer CF; Tea MK; Rappaport C; Mai PL; Greene MH; Sokolenko A; Imyanitov E; Toland AE; Senter L; Sweet K; Thomassen M; Gerdes AM; Kruse T; Caligo M; Aretini P; Rantala J; von Wachenfeld A; Henriksson K; ; Steele L; Neuhausen SL; Nussbaum R; Beattie M; Odunsi K; Sucheston L; Gayther SA; Nathanson K; Gross J; Walsh C; Karlan B; Chenevix-Trench G; Easton DF; Antoniou AC;
    Cancer Epidemiol Biomarkers Prev; 2012 Jan; 21(1):134-47. PubMed ID: 22144499
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  • 12. Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
    Spurdle AB; Couch FJ; Parsons MT; McGuffog L; Barrowdale D; Bolla MK; Wang Q; Healey S; Schmutzler R; Wappenschmidt B; Rhiem K; Hahnen E; Engel C; Meindl A; Ditsch N; Arnold N; Plendl H; Niederacher D; Sutter C; Wang-Gohrke S; Steinemann D; Preisler-Adams S; Kast K; Varon-Mateeva R; Ellis S; Frost D; Platte R; Perkins J; Evans DG; Izatt L; Eeles R; Adlard J; Davidson R; Cole T; Scuvera G; Manoukian S; Bonanni B; Mariette F; Fortuzzi S; Viel A; Pasini B; Papi L; Varesco L; Balleine R; Nathanson KL; Domchek SM; Offitt K; Jakubowska A; Lindor N; Thomassen M; Jensen UB; Rantala J; Borg Å; Andrulis IL; Miron A; Hansen TV; Caldes T; Neuhausen SL; Toland AE; Nevanlinna H; Montagna M; Garber J; Godwin AK; Osorio A; Factor RE; Terry MB; Rebbeck TR; Karlan BY; Southey M; Rashid MU; Tung N; Pharoah PD; Blows FM; Dunning AM; Provenzano E; Hall P; Czene K; Schmidt MK; Broeks A; Cornelissen S; Verhoef S; Fasching PA; Beckmann MW; Ekici AB; Slamon DJ; Bojesen SE; Nordestgaard BG; Nielsen SF; Flyger H; Chang-Claude J; Flesch-Janys D; Rudolph A; Seibold P; Aittomäki K; Muranen TA; Heikkilä P; Blomqvist C; Figueroa J; Chanock SJ; Brinton L; Lissowska J; Olson JE; Pankratz VS; John EM; Whittemore AS; West DW; Hamann U; Torres D; Ulmer HU; Rüdiger T; Devilee P; Tollenaar RA; Seynaeve C; Van Asperen CJ; Eccles DM; Tapper WJ; Durcan L; Jones L; Peto J; dos-Santos-Silva I; Fletcher O; Johnson N; Dwek M; Swann R; Bane AL; Glendon G; Mulligan AM; Giles GG; Milne RL; Baglietto L; McLean C; Carpenter J; Clarke C; Scott R; Brauch H; Brüning T; Ko YD; Cox A; Cross SS; Reed MW; Lubinski J; Jaworska-Bieniek K; Durda K; Gronwald J; Dörk T; Bogdanova N; Park-Simon TW; Hillemanns P; Haiman CA; Henderson BE; Schumacher F; Le Marchand L; Burwinkel B; Marme F; Surovy H; Yang R; Anton-Culver H; Ziogas A; Hooning MJ; Collée JM; Martens JW; Tilanus-Linthorst MM; Brenner H; Dieffenbach AK; Arndt V; Stegmaier C; Winqvist R; Pylkäs K; Jukkola-Vuorinen A; Grip M; Lindblom A; Margolin S; Joseph V; Robson M; Rau-Murthy R; González-Neira A; Arias JI; Zamora P; Benítez J; Mannermaa A; Kataja V; Kosma VM; Hartikainen JM; Peterlongo P; Zaffaroni D; Barile M; Capra F; Radice P; Teo SH; Easton DF; Antoniou AC; Chenevix-Trench G; Goldgar DE; ; ; ; ;
    Breast Cancer Res; 2014 Dec; 16(6):3419. PubMed ID: 25857409
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  • 13. Incorporating tumour pathology information into breast cancer risk prediction algorithms.
    Mavaddat N; Rebbeck TR; Lakhani SR; Easton DF; Antoniou AC
    Breast Cancer Res; 2010; 12(3):R28. PubMed ID: 20482762
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  • 14. Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers.
    Ramus SJ; Kartsonaki C; Gayther SA; Pharoah PD; Sinilnikova OM; Beesley J; Chen X; McGuffog L; Healey S; Couch FJ; Wang X; Fredericksen Z; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Roversi G; Barile M; Viel A; Allavena A; Ottini L; Papi L; Gismondi V; Capra F; Radice P; Greene MH; Mai PL; Andrulis IL; Glendon G; Ozcelik H; ; Thomassen M; Gerdes AM; Kruse TA; Cruger D; Jensen UB; Caligo MA; Olsson H; Kristoffersson U; Lindblom A; Arver B; Karlsson P; Stenmark Askmalm M; Borg A; Neuhausen SL; Ding YC; Nathanson KL; Domchek SM; Jakubowska A; Lubiński J; Huzarski T; Byrski T; Gronwald J; Górski B; Cybulski C; Dębniak T; Osorio A; Durán M; Tejada MI; Benítez J; Hamann U; Rookus MA; Verhoef S; Tilanus-Linthorst MA; Vreeswijk MP; Bodmer D; Ausems MG; van Os TA; Asperen CJ; Blok MJ; Meijers-Heijboer HE; ; ; Peock S; Cook M; Oliver C; Frost D; Dunning AM; Evans DG; Eeles R; Pichert G; Cole T; Hodgson S; Brewer C; Morrison PJ; Porteous M; Kennedy MJ; Rogers MT; Side LE; Donaldson A; Gregory H; Godwin A; Stoppa-Lyonnet D; Moncoutier V; Castera L; Mazoyer S; Barjhoux L; Bonadona V; Leroux D; Faivre L; Lidereau R; Nogues C; Bignon YJ; Prieur F; Collonge-Rame MA; Venat-Bouvet L; Fert-Ferrer S; ; Miron A; Buys SS; Hopper JL; Daly MB; John EM; Terry MB; Goldgar D; ; Hansen Tv; Jønson L; Ejlertsen B; Agnarsson BA; Offit K; Kirchhoff T; Vijai J; Dutra-Clarke AV; Przybylo JA; Montagna M; Casella C; Imyanitov EN; Janavicius R; Blanco I; Lázaro C; Moysich KB; Karlan BY; Gross J; Beattie MS; Schmutzler R; Wappenschmidt B; Meindl A; Ruehl I; Fiebig B; Sutter C; Arnold N; Deissler H; Varon-Mateeva R; Kast K; Niederacher D; Gadzicki D; Caldes T; de la Hoya M; Nevanlinna H; Aittomäki K; Simard J; Soucy P; ; Spurdle AB; Holland H; Chenevix-Trench G; Easton DF; Antoniou AC;
    J Natl Cancer Inst; 2011 Jan; 103(2):105-16. PubMed ID: 21169536
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  • 15. Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.
    Antoniou AC; Kuchenbaecker KB; Soucy P; Beesley J; Chen X; McGuffog L; Lee A; Barrowdale D; Healey S; Sinilnikova OM; Caligo MA; Loman N; Harbst K; Lindblom A; Arver B; Rosenquist R; Karlsson P; Nathanson K; Domchek S; Rebbeck T; Jakubowska A; Lubinski J; Jaworska K; Durda K; Złowowcka-Perłowska E; Osorio A; Durán M; Andrés R; Benítez J; Hamann U; Hogervorst FB; van Os TA; Verhoef S; Meijers-Heijboer HE; Wijnen J; Gómez Garcia EB; Ligtenberg MJ; Kriege M; Collée JM; Ausems MG; Oosterwijk JC; Peock S; Frost D; Ellis SD; Platte R; Fineberg E; Evans DG; Lalloo F; Jacobs C; Eeles R; Adlard J; Davidson R; Cole T; Cook J; Paterson J; Douglas F; Brewer C; Hodgson S; Morrison PJ; Walker L; Rogers MT; Donaldson A; Dorkins H; Godwin AK; Bove B; Stoppa-Lyonnet D; Houdayer C; Buecher B; de Pauw A; Mazoyer S; Calender A; Léoné M; Bressac-de Paillerets B; Caron O; Sobol H; Frenay M; Prieur F; Ferrer SU; Mortemousque I; Buys S; Daly M; Miron A; Terry MU; Hopper JL; John EM; Southey M; Goldgar D; Singer CF; Fink-Retter A; Tea MK; Kaulich DU; Hansen TV; Nielsen FC; Barkardottir RB; Gaudet M; Kirchhoff T; Joseph V; Dutra-Clarke A; Offit K; Piedmonte M; Kirk J; Cohn D; Hurteau J; Byron J; Fiorica J; Toland AE; Montagna M; Oliani C; Imyanitov E; Isaacs C; Tihomirova L; Blanco I; Lazaro C; Teulé A; Valle JD; Gayther SA; Odunsi K; Gross J; Karlan BY; Olah E; Teo SH; Ganz PA; Beattie MS; Dorfling CM; van Rensburg EU; Diez O; Kwong A; Schmutzler RK; Wappenschmidt B; Engel C; Meindl A; Ditsch N; Arnold N; Heidemann S; Niederacher D; Preisler-Adams S; Gadzicki D; Varon-Mateeva R; Deissler H; Gehrig A; Sutter C; Kast K; Fiebig B; Schäfer D; Caldes T; de la Hoya M; Nevanlinna H; Muranen TA; Lespérance B; Spurdle AB; Neuhausen SL; Ding YC; Wang X; Fredericksen Z; Pankratz VS; Lindor NM; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Bonanni B; Bernard L; Dolcetti R; Papi L; Ottini L; Radice P; Greene MH; Loud JT; Andrulis IL; Ozcelik H; Mulligan AU; Glendon G; Thomassen M; Gerdes AM; Jensen UB; Skytte AB; Kruse TA; Chenevix-Trench G; Couch FJ; Simard J; Easton DF; ; ; ; ;
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  • 16. Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk.
    Gaudet MM; Kuchenbaecker KB; Vijai J; Klein RJ; Kirchhoff T; McGuffog L; Barrowdale D; Dunning AM; Lee A; Dennis J; Healey S; Dicks E; Soucy P; Sinilnikova OM; Pankratz VS; Wang X; Eldridge RC; Tessier DC; Vincent D; Bacot F; Hogervorst FB; Peock S; Stoppa-Lyonnet D; ; Peterlongo P; Schmutzler RK; Nathanson KL; Piedmonte M; Singer CF; Thomassen M; ; Hansen Tv; Neuhausen SL; Blanco I; Greene MH; Garber J; Weitzel JN; Andrulis IL; Goldgar DE; D'Andrea E; Caldes T; Nevanlinna H; Osorio A; van Rensburg EJ; Arason A; Rennert G; van den Ouweland AM; van der Hout AH; Kets CM; Aalfs CM; Wijnen JT; Ausems MG; ; ; Frost D; Ellis S; Fineberg E; Platte R; Evans DG; Jacobs C; Adlard J; Tischkowitz M; Porteous ME; Damiola F; ; Golmard L; Barjhoux L; Longy M; Belotti M; Ferrer SF; Mazoyer S; Spurdle AB; Manoukian S; Barile M; Genuardi M; Arnold N; Meindl A; Sutter C; Wappenschmidt B; Domchek SM; Pfeiler G; Friedman E; Jensen UB; Robson M; Shah S; Lazaro C; Mai PL; Benitez J; Southey MC; Schmidt MK; Fasching PA; Peto J; Humphreys MK; Wang Q; Michailidou K; Sawyer EJ; Burwinkel B; Guénel P; Bojesen SE; Milne RL; Brenner H; Lochmann M; ; Aittomäki K; Dörk T; Margolin S; Mannermaa A; Lambrechts D; Chang-Claude J; Radice P; Giles GG; Haiman CA; Winqvist R; Devillee P; García-Closas M; Schoof N; Hooning MJ; Cox A; Pharoah PD; Jakubowska A; Orr N; González-Neira A; Pita G; Alonso MR; Hall P; Couch FJ; Simard J; Altshuler D; Easton DF; Chenevix-Trench G; Antoniou AC; Offit K
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  • 17. AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.
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  • 18. The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
    Sinilnikova OM; Antoniou AC; Simard J; Healey S; Léoné M; Sinnett D; Spurdle AB; Beesley J; Chen X; ; Greene MH; Loud JT; Lejbkowicz F; Rennert G; Dishon S; Andrulis IL; ; Domchek SM; Nathanson KL; Manoukian S; Radice P; Konstantopoulou I; Blanco I; Laborde AL; Durán M; Osorio A; Benitez J; Hamann U; Hogervorst FB; van Os TA; Gille HJ; ; Peock S; Cook M; Luccarini C; Evans DG; Lalloo F; Eeles R; Pichert G; Davidson R; Cole T; Cook J; Paterson J; Brewer C; ; Hughes DJ; Coupier I; Giraud S; Coulet F; Colas C; Soubrier F; Rouleau E; Bièche I; Lidereau R; Demange L; Nogues C; Lynch HT; ; Schmutzler RK; Versmold B; Engel C; Meindl A; Arnold N; Sutter C; Deissler H; Schaefer D; Froster UG; ; Aittomäki K; Nevanlinna H; McGuffog L; Easton DF; Chenevix-Trench G; Stoppa-Lyonnet D;
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  • 19. Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).
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  • 20. A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.
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