BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 22056382)

  • 1. Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice.
    Maniati E; Bossard M; Cook N; Candido JB; Emami-Shahri N; Nedospasov SA; Balkwill FR; Tuveson DA; Hagemann T
    J Clin Invest; 2011 Dec; 121(12):4685-99. PubMed ID: 22056382
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.
    Daniluk J; Liu Y; Deng D; Chu J; Huang H; Gaiser S; Cruz-Monserrate Z; Wang H; Ji B; Logsdon CD
    J Clin Invest; 2012 Apr; 122(4):1519-28. PubMed ID: 22406536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
    Zhang S; Chung WC; Xu K
    Oncogene; 2016 May; 35(19):2485-95. PubMed ID: 26279302
    [TBL] [Abstract][Full Text] [Related]  

  • 4. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
    Ling J; Kang Y; Zhao R; Xia Q; Lee DF; Chang Z; Li J; Peng B; Fleming JB; Wang H; Liu J; Lemischka IR; Hung MC; Chiao PJ
    Cancer Cell; 2012 Jan; 21(1):105-20. PubMed ID: 22264792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways.
    Vasseur R; Skrypek N; Duchêne B; Renaud F; Martínez-Maqueda D; Vincent A; Porchet N; Van Seuningen I; Jonckheere N
    Biochim Biophys Acta; 2015 Dec; 1849(12):1375-84. PubMed ID: 26477488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
    Chalabi-Dchar M; Cassant-Sourdy S; Duluc C; Fanjul M; Lulka H; Samain R; Roche C; Breibach F; Delisle MB; Poupot M; Dufresne M; Shimaoka T; Yonehara S; Mathonnet M; Pyronnet S; Bousquet C
    Gastroenterology; 2015 Jun; 148(7):1452-65. PubMed ID: 25683115
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HES 1 is essential for chemoresistance induced by stellate cells and is associated with poor prognosis in pancreatic cancer.
    Cao F; Li J; Sun H; Liu S; Cui Y; Li F
    Oncol Rep; 2015 Apr; 33(4):1883-9. PubMed ID: 25672829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
    Chen NM; Singh G; Koenig A; Liou GY; Storz P; Zhang JS; Regul L; Nagarajan S; Kühnemuth B; Johnsen SA; Hebrok M; Siveke J; Billadeau DD; Ellenrieder V; Hessmann E
    Gastroenterology; 2015 May; 148(5):1024-1034.e9. PubMed ID: 25623042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk.
    Thounaojam MC; Dudimah DF; Pellom ST; Uzhachenko RV; Carbone DP; Dikov MM; Shanker A
    Oncotarget; 2015 Oct; 6(32):32439-55. PubMed ID: 26431276
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
    Wang Z; Banerjee S; Ahmad A; Li Y; Azmi AS; Gunn JR; Kong D; Bao B; Ali S; Gao J; Mohammad RM; Miele L; Korc M; Sarkar FH
    PLoS One; 2011; 6(6):e20537. PubMed ID: 21673986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle.
    Hu W; Li F; Mahavadi S; Murthy KS
    Biochem J; 2008 May; 412(1):35-43. PubMed ID: 18260825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.
    Alaña L; Sesé M; Cánovas V; Punyal Y; Fernández Y; Abasolo I; de Torres I; Ruiz C; Espinosa L; Bigas A; Y Cajal SR; Fernández PL; Serras F; Corominas M; Thomson TM; Paciucci R
    Mol Cancer; 2014 Mar; 13():74. PubMed ID: 24684754
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.
    Fujioka S; Sclabas GM; Schmidt C; Niu J; Frederick WA; Dong QG; Abbruzzese JL; Evans DB; Baker C; Chiao PJ
    Oncogene; 2003 Mar; 22(9):1365-70. PubMed ID: 12618762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer.
    Döppler H; Panayiotou R; Reid EM; Maimo W; Bastea L; Storz P
    Sci Rep; 2016 Sep; 6():33758. PubMed ID: 27649783
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.
    Zhang H; Hilton MJ; Anolik JH; Welle SL; Zhao C; Yao Z; Li X; Wang Z; Boyce BF; Xing L
    J Clin Invest; 2014 Jul; 124(7):3200-14. PubMed ID: 24892805
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas.
    Maier HJ; Wagner M; Schips TG; Salem HH; Baumann B; Wirth T
    Oncogene; 2013 May; 32(21):2690-5. PubMed ID: 22751123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer.
    Abel EV; Kim EJ; Wu J; Hynes M; Bednar F; Proctor E; Wang L; Dziubinski ML; Simeone DM
    PLoS One; 2014; 9(3):e91983. PubMed ID: 24647545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interleukin-17 activates and synergizes with the notch signaling pathway in the progression of pancreatic ductal adenocarcinoma.
    Wang X; Chen H; Jiang R; Hong X; Peng J; Chen W; Jiang J; Li J; Huang D; Dai H; Wang W; Lu J; Zhao Y; Wu W
    Cancer Lett; 2021 Jun; 508():1-12. PubMed ID: 33713738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
    Qiu W; Tang SM; Lee S; Turk AT; Sireci AN; Qiu A; Rose C; Xie C; Kitajewski J; Wen HJ; Crawford HC; Sims PA; Hruban RH; Remotti HE; Su GH
    Gastroenterology; 2016 Jan; 150(1):218-228.e12. PubMed ID: 26408346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.