131 related articles for article (PubMed ID: 22056744)
1. Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.
Matuszak N; Es Saadi B; Labar G; Marchand-Brynaert J; Lambert DM
Bioorg Med Chem Lett; 2011 Dec; 21(24):7321-4. PubMed ID: 22056744
[TBL] [Abstract][Full Text] [Related]
2. The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors.
Szabo M; Agostino M; Malone DT; Yuriev E; Capuano B
Bioorg Med Chem Lett; 2011 Nov; 21(22):6782-7. PubMed ID: 21982493
[TBL] [Abstract][Full Text] [Related]
3. A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.
King AR; Lodola A; Carmi C; Fu J; Mor M; Piomelli D
Br J Pharmacol; 2009 Jul; 157(6):974-83. PubMed ID: 19486005
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.
Kapanda CN; Masquelier J; Labar G; Muccioli GG; Poupaert JH; Lambert DM
J Med Chem; 2012 Jun; 55(12):5774-83. PubMed ID: 22651858
[TBL] [Abstract][Full Text] [Related]
5. Disulfiram is an inhibitor of human purified monoacylglycerol lipase, the enzyme regulating 2-arachidonoylglycerol signaling.
Labar G; Bauvois C; Muccioli GG; Wouters J; Lambert DM
Chembiochem; 2007 Jul; 8(11):1293-7. PubMed ID: 17579916
[TBL] [Abstract][Full Text] [Related]
6. Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold.
Bononi G; Tonarini G; Poli G; Barravecchia I; Caligiuri I; Macchia M; Rizzolio F; Demontis GC; Minutolo F; Granchi C; Tuccinardi T
Eur J Med Chem; 2021 Nov; 223():113679. PubMed ID: 34218085
[TBL] [Abstract][Full Text] [Related]
7. Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors.
Bononi G; Granchi C; Lapillo M; Giannotti M; Nieri D; Fortunato S; Boustani ME; Caligiuri I; Poli G; Carlson KE; Kim SH; Macchia M; Martinelli A; Rizzolio F; Chicca A; Katzenellenbogen JA; Minutolo F; Tuccinardi T
Eur J Med Chem; 2018 Sep; 157():817-836. PubMed ID: 30144699
[TBL] [Abstract][Full Text] [Related]
8. Development of Thiazole-5-carboxylate Derivatives as Selective Inhibitors of Monoacylglycerol Lipase as Target in Cancer.
Ali MR; Kumar S; Shalmali N; Afzal O; Azim S; Chanana D; Alam O; Paudel YN; Sharma M; Bawa S
Mini Rev Med Chem; 2019; 19(5):410-423. PubMed ID: 29962341
[TBL] [Abstract][Full Text] [Related]
9. (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
Holtfrerich A; Hanekamp W; Lehr M
Eur J Med Chem; 2013 May; 63():64-75. PubMed ID: 23455058
[TBL] [Abstract][Full Text] [Related]
10. High-performance liquid chromatography assay with fluorescence detection for the evaluation of inhibitors against human recombinant monoacylglycerol lipase.
Holtfrerich A; Makharadze T; Lehr M
Anal Biochem; 2010 Apr; 399(2):218-24. PubMed ID: 20015447
[TBL] [Abstract][Full Text] [Related]
11. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.
Butler CR; Beck EM; Harris A; Huang Z; McAllister LA; Am Ende CW; Fennell K; Foley TL; Fonseca K; Hawrylik SJ; Johnson DS; Knafels JD; Mente S; Noell GS; Pandit J; Phillips TB; Piro JR; Rogers BN; Samad TA; Wang J; Wan S; Brodney MA
J Med Chem; 2017 Dec; 60(23):9860-9873. PubMed ID: 29148769
[TBL] [Abstract][Full Text] [Related]
12. The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL).
Zhu B; Connolly PJ; Zhang SP; Chevalier KM; Milligan CM; Flores CM; Macielag MJ
Bioorg Med Chem Lett; 2020 Jun; 30(12):127198. PubMed ID: 32334914
[TBL] [Abstract][Full Text] [Related]
13. Docking based virtual screening and molecular dynamics study to identify potential monoacylglycerol lipase inhibitors.
Afzal O; Kumar S; Kumar R; Firoz A; Jaggi M; Bawa S
Bioorg Med Chem Lett; 2014 Aug; 24(16):3986-96. PubMed ID: 25011912
[TBL] [Abstract][Full Text] [Related]
14. Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors.
Kapanda CN; Muccioli GG; Labar G; Poupaert JH; Lambert DM
J Med Chem; 2009 Nov; 52(22):7310-4. PubMed ID: 19883085
[TBL] [Abstract][Full Text] [Related]
15. Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.
Castelli R; Scalvini L; Vacondio F; Lodola A; Anselmi M; Vezzosi S; Carmi C; Bassi M; Ferlenghi F; Rivara S; Møller IR; Rand KD; Daglian J; Wei D; Dotsey EY; Ahmed F; Jung KM; Stella N; Singh S; Mor M; Piomelli D
J Med Chem; 2020 Feb; 63(3):1261-1280. PubMed ID: 31714779
[TBL] [Abstract][Full Text] [Related]
16. The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors.
Zhu B; Connolly PJ; Zhang YM; McDonnell ME; Bian H; Lin SC; Liu L; Zhang SP; Chevalier KM; Brandt MR; Milligan CM; Flores CM; Macielag MJ
Bioorg Med Chem Lett; 2020 Jul; 30(14):127243. PubMed ID: 32527545
[TBL] [Abstract][Full Text] [Related]
17. A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).
Granchi C; Caligiuri I; Minutolo F; Rizzolio F; Tuccinardi T
Expert Opin Ther Pat; 2017 Dec; 27(12):1341-1351. PubMed ID: 29053063
[TBL] [Abstract][Full Text] [Related]
18. Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold.
Morera L; Labar G; Ortar G; Lambert DM
Bioorg Med Chem; 2012 Nov; 20(21):6260-75. PubMed ID: 23036333
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.
Granchi C; Bononi G; Ferrisi R; Gori E; Mantini G; Glasmacher S; Poli G; Palazzolo S; Caligiuri I; Rizzolio F; Canzonieri V; Perin T; Gertsch J; Sodi A; Giovannetti E; Macchia M; Minutolo F; Tuccinardi T; Chicca A
Eur J Med Chem; 2021 Jan; 209():112857. PubMed ID: 33045662
[TBL] [Abstract][Full Text] [Related]
20. Monoacylglycerol lipase (MAGL) as a promising therapeutic target.
Gil-Ordóñez A; Martín-Fontecha M; Ortega-Gutiérrez S; López-Rodríguez ML
Biochem Pharmacol; 2018 Nov; 157():18-32. PubMed ID: 30059673
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
