BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 22056774)

  • 21. The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex.
    Song MS; Song SJ; Kim SY; Oh HJ; Lim DS
    EMBO J; 2008 Jul; 27(13):1863-74. PubMed ID: 18566590
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.
    Meulmeester E; Maurice MM; Boutell C; Teunisse AF; Ovaa H; Abraham TE; Dirks RW; Jochemsen AG
    Mol Cell; 2005 May; 18(5):565-76. PubMed ID: 15916963
    [TBL] [Abstract][Full Text] [Related]  

  • 23. p53 tumor suppressor protein stability and transcriptional activity are targeted by Kaposi's sarcoma-associated herpesvirus-encoded viral interferon regulatory factor 3.
    Baresova P; Musilova J; Pitha PM; Lubyova B
    Mol Cell Biol; 2014 Feb; 34(3):386-99. PubMed ID: 24248600
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dynamics in the p53-Mdm2 ubiquitination pathway.
    Brooks CL; Gu W
    Cell Cycle; 2004 Jul; 3(7):895-9. PubMed ID: 15254415
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Targeting HAUSP in both p53 wildtype and p53-mutant tumors.
    Tavana O; Sun H; Gu W
    Cell Cycle; 2018; 17(7):823-828. PubMed ID: 29616860
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase.
    Xiang Q; Ju H; Li Q; Mei SC; Chen D; Choi YB; Nicholas J
    J Virol; 2018 Apr; 92(7):. PubMed ID: 29343584
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.
    Saridakis V; Sheng Y; Sarkari F; Holowaty MN; Shire K; Nguyen T; Zhang RG; Liao J; Lee W; Edwards AM; Arrowsmith CH; Frappier L
    Mol Cell; 2005 Apr; 18(1):25-36. PubMed ID: 15808506
    [TBL] [Abstract][Full Text] [Related]  

  • 28. HAUSP-regulated switch from auto- to p53 ubiquitination by Mdm2 (in silico discovery).
    Brazhnik P; Kohn KW
    Math Biosci; 2007 Nov; 210(1):60-77. PubMed ID: 17585950
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cooperation between viral interferon regulatory factor 4 and RTA to activate a subset of Kaposi's sarcoma-associated herpesvirus lytic promoters.
    Xi X; Persson LM; O'Brien MW; Mohr I; Wilson AC
    J Virol; 2012 Jan; 86(2):1021-33. PubMed ID: 22090118
    [TBL] [Abstract][Full Text] [Related]  

  • 30. HAUSP/USP7 as an Epstein-Barr virus target.
    Holowaty MN; Frappier L
    Biochem Soc Trans; 2004 Nov; 32(Pt 5):731-2. PubMed ID: 15494000
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359.
    Rodriguez J; Herrero A; Li S; Rauch N; Quintanilla A; Wynne K; Krstic A; Acosta JC; Taylor C; Schlisio S; von Kriegsheim A
    Cell Rep; 2018 Jul; 24(5):1316-1329. PubMed ID: 30067985
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Daxx is reciprocally regulated by Mdm2 and Hausp.
    Tang J; Qu L; Pang M; Yang X
    Biochem Biophys Res Commun; 2010 Mar; 393(3):542-5. PubMed ID: 20153724
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.
    Faesen AC; Dirac AM; Shanmugham A; Ovaa H; Perrakis A; Sixma TK
    Mol Cell; 2011 Oct; 44(1):147-59. PubMed ID: 21981925
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Critical role for Daxx in regulating Mdm2.
    Tang J; Qu LK; Zhang J; Wang W; Michaelson JS; Degenhardt YY; El-Deiry WS; Yang X
    Nat Cell Biol; 2006 Aug; 8(8):855-62. PubMed ID: 16845383
    [TBL] [Abstract][Full Text] [Related]  

  • 35. MDM2 small-molecule antagonist RG7112 activates p53 signaling and regresses human tumors in preclinical cancer models.
    Tovar C; Graves B; Packman K; Filipovic Z; Higgins B; Xia M; Tardell C; Garrido R; Lee E; Kolinsky K; To KH; Linn M; Podlaski F; Wovkulich P; Vu B; Vassilev LT
    Cancer Res; 2013 Apr; 73(8):2587-97. PubMed ID: 23400593
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP.
    Holowaty MN; Sheng Y; Nguyen T; Arrowsmith C; Frappier L
    J Biol Chem; 2003 Nov; 278(48):47753-61. PubMed ID: 14506283
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.
    Yi P; Xia W; Wu RC; Lonard DM; Hung MC; O'Malley BW
    Genes Dev; 2013 Feb; 27(3):274-87. PubMed ID: 23388826
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The HAUSP gene plays an important role in non-small cell lung carcinogenesis through p53-dependent pathways.
    Masuya D; Huang C; Liu D; Nakashima T; Yokomise H; Ueno M; Nakashima N; Sumitomo S
    J Pathol; 2006 Apr; 208(5):724-32. PubMed ID: 16450335
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4) targets expression of cellular IRF4 and the Myc gene to facilitate lytic replication.
    Lee HR; Doğanay S; Chung B; Toth Z; Brulois K; Lee S; Kanketayeva Z; Feng P; Ha T; Jung JU
    J Virol; 2014 Feb; 88(4):2183-94. PubMed ID: 24335298
    [TBL] [Abstract][Full Text] [Related]  

  • 40. USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.
    Sarkari F; Sheng Y; Frappier L
    PLoS One; 2010 Sep; 5(9):e13040. PubMed ID: 20885946
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.