BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 22056873)

  • 1. Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.
    Gajate C; Matos-da-Silva M; Dakir el-H; Fonteriz RI; Alvarez J; Mollinedo F
    Oncogene; 2012 May; 31(21):2627-39. PubMed ID: 22056873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.
    Nieto-Miguel T; Fonteriz RI; Vay L; Gajate C; López-Hernández S; Mollinedo F
    Cancer Res; 2007 Nov; 67(21):10368-78. PubMed ID: 17974980
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine.
    Bonilla X; Dakir el-H; Mollinedo F; Gajate C
    Oncotarget; 2015 Jun; 6(16):14596-613. PubMed ID: 25999349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine.
    Gajate C; Mollinedo F
    Anticancer Agents Med Chem; 2014 May; 14(4):509-27. PubMed ID: 24628241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells.
    Nieto-Miguel T; Gajate C; Mollinedo F
    J Biol Chem; 2006 May; 281(21):14833-40. PubMed ID: 16540473
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.
    Mollinedo F; de la Iglesia-Vicente J; Gajate C; Estella-Hermoso de Mendoza A; Villa-Pulgarin JA; de Frias M; Roué G; Gil J; Colomer D; Campanero MA; Blanco-Prieto MJ
    Clin Cancer Res; 2010 Apr; 16(7):2046-54. PubMed ID: 20233887
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer.
    Mollinedo F; Gajate C
    Cancers (Basel); 2021 Aug; 13(16):. PubMed ID: 34439330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.
    Nawrocki ST; Carew JS; Pino MS; Highshaw RA; Dunner K; Huang P; Abbruzzese JL; McConkey DJ
    Cancer Res; 2005 Dec; 65(24):11658-66. PubMed ID: 16357177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
    Nawrocki ST; Carew JS; Dunner K; Boise LH; Chiao PJ; Huang P; Abbruzzese JL; McConkey DJ
    Cancer Res; 2005 Dec; 65(24):11510-9. PubMed ID: 16357160
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition.
    Gajate C; Gayet O; Fraunhoffer NA; Iovanna J; Dusetti N; Mollinedo F
    Cancers (Basel); 2021 Dec; 13(23):. PubMed ID: 34885233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling.
    Park SK; Sanders BG; Kline K
    Breast Cancer Res Treat; 2010 Nov; 124(2):361-75. PubMed ID: 20157774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress.
    Cheng S; Swanson K; Eliaz I; McClintick JN; Sandusky GE; Sliva D
    PLoS One; 2015; 10(4):e0122270. PubMed ID: 25915041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proapoptotic role of Hsp90 by its interaction with c-Jun N-terminal kinase in lipid rafts in edelfosine-mediated antileukemic therapy.
    Nieto-Miguel T; Gajate C; González-Camacho F; Mollinedo F
    Oncogene; 2008 Mar; 27(12):1779-87. PubMed ID: 17891170
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57.
    Corazzari M; Lovat PE; Armstrong JL; Fimia GM; Hill DS; Birch-Machin M; Redfern CP; Piacentini M
    Br J Cancer; 2007 Apr; 96(7):1062-71. PubMed ID: 17353921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antitumor alkyl ether lipid edelfosine: tissue distribution and pharmacokinetic behavior in healthy and tumor-bearing immunosuppressed mice.
    Estella-Hermoso de Mendoza A; Campanero MA; de la Iglesia-Vicente J; Gajate C; Mollinedo F; Blanco-Prieto MJ
    Clin Cancer Res; 2009 Feb; 15(3):858-64. PubMed ID: 19188156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine.
    Villa-Pulgarín JA; Gajate C; Botet J; Jimenez A; Justies N; Varela-M RE; Cuesta-Marbán Á; Müller I; Modolell M; Revuelta JL; Mollinedo F
    PLoS Negl Trop Dis; 2017 Aug; 11(8):e0005805. PubMed ID: 28829771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress.
    Huang H; Hua X; Liu N; Li X; Liu S; Chen X; Zhao C; Lan X; Yang C; Dou QP; Liu J
    Toxicol Lett; 2014 Aug; 228(3):170-8. PubMed ID: 24853302
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ER-Dependent Ca++-mediated Cytosolic ROS as an Effector for Induction of Mitochondrial Apoptotic and ATM-JNK Signal Pathways in Gallic Acid-treated Human Oral Cancer Cells.
    Lu YC; Lin ML; Su HL; Chen SS
    Anticancer Res; 2016 Feb; 36(2):697-705. PubMed ID: 26851027
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endoplasmic reticulum stress activation mediates Ginseng Rg3-induced anti-gallbladder cancer cell activity.
    Wu K; Li N; Sun H; Xu T; Jin F; Nie J
    Biochem Biophys Res Commun; 2015 Oct; 466(3):369-75. PubMed ID: 26361144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult.
    Yeh TC; Chiang PC; Li TK; Hsu JL; Lin CJ; Wang SW; Peng CY; Guh JH
    Biochem Pharmacol; 2007 Mar; 73(6):782-92. PubMed ID: 17188247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.