BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 22063096)

  • 1. Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity.
    Street TO; Lavery LA; Verba KA; Lee CT; Mayer MP; Agard DA
    J Mol Biol; 2012 Jan; 415(1):3-15. PubMed ID: 22063096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle.
    Richter K; Reinstein J; Buchner J
    J Biol Chem; 2002 Nov; 277(47):44905-10. PubMed ID: 12235160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones.
    Li J; Soroka J; Buchner J
    Biochim Biophys Acta; 2012 Mar; 1823(3):624-35. PubMed ID: 21951723
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of the weak ATPase activity of human hsp90 by a client protein.
    McLaughlin SH; Smith HW; Jackson SE
    J Mol Biol; 2002 Jan; 315(4):787-98. PubMed ID: 11812147
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinated ATP hydrolysis by the Hsp90 dimer.
    Richter K; Muschler P; Hainzl O; Buchner J
    J Biol Chem; 2001 Sep; 276(36):33689-96. PubMed ID: 11441008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site.
    Harris SF; Shiau AK; Agard DA
    Structure; 2004 Jun; 12(6):1087-97. PubMed ID: 15274928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.
    Ali MM; Roe SM; Vaughan CK; Meyer P; Panaretou B; Piper PW; Prodromou C; Pearl LH
    Nature; 2006 Apr; 440(7087):1013-7. PubMed ID: 16625188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
    Richter K; Walter S; Buchner J
    J Mol Biol; 2004 Oct; 342(5):1403-13. PubMed ID: 15364569
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure and mechanism of the Hsp90 molecular chaperone machinery.
    Pearl LH; Prodromou C
    Annu Rev Biochem; 2006; 75():271-94. PubMed ID: 16756493
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer.
    Morra G; Verkhivker G; Colombo G
    PLoS Comput Biol; 2009 Mar; 5(3):e1000323. PubMed ID: 19300478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel quaternary domain interactions in the Hsp90 chaperone, GRP94.
    Chu F; Maynard JC; Chiosis G; Nicchitta CV; Burlingame AL
    Protein Sci; 2006 Jun; 15(6):1260-9. PubMed ID: 16731965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.
    Young JC; Hartl FU
    EMBO J; 2000 Nov; 19(21):5930-40. PubMed ID: 11060043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
    Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
    J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.
    Siligardi G; Hu B; Panaretou B; Piper PW; Pearl LH; Prodromou C
    J Biol Chem; 2004 Dec; 279(50):51989-98. PubMed ID: 15466438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence.
    Scheibel T; Weikl T; Buchner J
    Proc Natl Acad Sci U S A; 1998 Feb; 95(4):1495-9. PubMed ID: 9465043
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization.
    Allan RK; Mok D; Ward BK; Ratajczak T
    J Biol Chem; 2006 Mar; 281(11):7161-71. PubMed ID: 16421106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor.
    Tassone G; Mazzorana M; Mangani S; Petricci E; Cini E; Giannini G; Pozzi C; Maramai S
    Int J Mol Sci; 2022 Aug; 23(16):. PubMed ID: 36012721
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.
    Prodromou C; Panaretou B; Chohan S; Siligardi G; O'Brien R; Ladbury JE; Roe SM; Piper PW; Pearl LH
    EMBO J; 2000 Aug; 19(16):4383-92. PubMed ID: 10944121
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.
    Brychzy A; Rein T; Winklhofer KF; Hartl FU; Young JC; Obermann WM
    EMBO J; 2003 Jul; 22(14):3613-23. PubMed ID: 12853476
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.
    Roiniotis J; Masendycz P; Ho S; Scholz GM
    Biochemistry; 2005 May; 44(17):6662-9. PubMed ID: 15850399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.