These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
184 related articles for article (PubMed ID: 22064363)
1. Peroxidase-mediated dealkylation of tamoxifen, detected by electrospray ionization-mass spectrometry, and activation to form DNA adducts. Gaikwad NW; Bodell WJ Free Radic Biol Med; 2012 Jan; 52(2):340-7. PubMed ID: 22064363 [TBL] [Abstract][Full Text] [Related]
2. Oxidation of eugenol to form DNA adducts and 8-hydroxy-2'-deoxyguanosine: role of quinone methide derivative in DNA adduct formation. Bodell WJ; Ye Q; Pathak DN; Pongracz K Carcinogenesis; 1998 Mar; 19(3):437-43. PubMed ID: 9525278 [TBL] [Abstract][Full Text] [Related]
3. Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen. Pathak DN; Pongracz K; Bodell WJ Carcinogenesis; 1996 Sep; 17(9):1785-90. PubMed ID: 8824496 [TBL] [Abstract][Full Text] [Related]
4. Microsomal and peroxidase activation of 4-hydroxy-tamoxifen to form DNA adducts: comparison with DNA adducts formed in Sprague-Dawley rats treated with tamoxifen. Pathak DN; Pongracz K; Bodell WJ Carcinogenesis; 1995 Jan; 16(1):11-5. PubMed ID: 7834794 [TBL] [Abstract][Full Text] [Related]
5. Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days. Schild LJ; Divi RL; Beland FA; Churchwell MI; Doerge DR; Gamboa da Costa G; Marques MM; Poirier MC Cancer Res; 2003 Sep; 63(18):5999-6003. PubMed ID: 14522927 [TBL] [Abstract][Full Text] [Related]
6. Electrospray ionization-tandem mass spectrometry and 32P-postlabeling analyses of tamoxifen-DNA adducts in humans. Beland FA; Churchwell MI; Doerge DR; Parkin DR; Malejka-Giganti D; Hewer A; Phillips DH; Carmichael PL; Gamboa da Costa G; Marques MM J Natl Cancer Inst; 2004 Jul; 96(14):1099-104. PubMed ID: 15265972 [TBL] [Abstract][Full Text] [Related]
7. Formation of DNA adducts by microsomal and peroxidase activation of p-cresol: role of quinone methide in DNA adduct formation. Gaikwad NW; Bodell WJ Chem Biol Interact; 2001 Dec; 138(3):217-29. PubMed ID: 11714480 [TBL] [Abstract][Full Text] [Related]
8. Bioactivation of tamoxifen to metabolite E quinone methide: reaction with glutathione and DNA. Fan PW; Bolton JL Drug Metab Dispos; 2001 Jun; 29(6):891-6. PubMed ID: 11353759 [TBL] [Abstract][Full Text] [Related]
9. The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk. Williams-Brown MY; Salih SM; Xu X; Veenstra TD; Saeed M; Theiler SK; Diaz-Arrastia CR; Salama SA J Steroid Biochem Mol Biol; 2011 Sep; 126(3-5):78-86. PubMed ID: 21600284 [TBL] [Abstract][Full Text] [Related]
10. Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of alpha-hydroxytamoxifen in rat and human livers. Kim SY; Laxmi YR; Suzuki N; Ogura K; Watabe T; Duffel MW; Shibutani S Drug Metab Dispos; 2005 Nov; 33(11):1673-8. PubMed ID: 16099924 [TBL] [Abstract][Full Text] [Related]
11. Hepatic DNA adduct dosimetry in rats fed tamoxifen: a comparison of methods. Schild LJ; Phillips DH; Osborne MR; Hewer A; Beland FA; Churchwell MI; Brown K; Gaskell M; Wright E; Poirier MC Mutagenesis; 2005 Mar; 20(2):115-24. PubMed ID: 15755801 [TBL] [Abstract][Full Text] [Related]
12. Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts. Davies AM; Martin EA; Jones RM; Lim CK; Smith LL; White IN Carcinogenesis; 1995 Mar; 16(3):539-45. PubMed ID: 7697811 [TBL] [Abstract][Full Text] [Related]
13. Quantification of tamoxifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry. Gamboa da Costa G; Marques MM; Beland FA; Freeman JP; Churchwell MI; Doerge DR Chem Res Toxicol; 2003 Mar; 16(3):357-66. PubMed ID: 12641436 [TBL] [Abstract][Full Text] [Related]
14. Formation of tamoxifen-DNA adducts in human endometrial explants exposed to alpha-hydroxytamoxifen. Kim SY; Suzuki N; Laxmi YR; McGarrigle BP; Olson JR; Sharma M; Sharma M; Shibutani S Chem Res Toxicol; 2005 May; 18(5):889-95. PubMed ID: 15892583 [TBL] [Abstract][Full Text] [Related]
15. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones. Yao D; Zhang F; Yu L; Yang Y; van Breemen RB; Bolton JL Chem Res Toxicol; 2001 Dec; 14(12):1643-53. PubMed ID: 11743747 [TBL] [Abstract][Full Text] [Related]
16. Activation of the tamoxifen derivative metabolite E to form DNA adducts: comparison with the adducts formed by microsomal activation of tamoxifen. Pongracz K; Pathak DN; Nakamura T; Burlingame AL; Bodell WJ Cancer Res; 1995 Jul; 55(14):3012-5. PubMed ID: 7606720 [TBL] [Abstract][Full Text] [Related]
17. Determination of tamoxifen--DNA adducts in leukocytes from breast cancer patients treated with tamoxifen. Umemoto A; Monden Y; Lin CX; Abdul-Momen M; Ueyama Y; Komaki K; Laxmi YR; Shibutani S Chem Res Toxicol; 2004 Dec; 17(12):1577-83. PubMed ID: 15606132 [TBL] [Abstract][Full Text] [Related]
18. Nucleobase-dependent reactivity of a quinone metabolite of pentachlorophenol. Vaidyanathan VG; Villalta PW; Sturla SJ Chem Res Toxicol; 2007 Jun; 20(6):913-9. PubMed ID: 17497895 [TBL] [Abstract][Full Text] [Related]
19. Mutagenic potential of alpha-(N2-deoxyguanosinyl)tamoxifen lesions, the major DNA adducts detected in endometrial tissues of patients treated with tamoxifen. Terashima I; Suzuki N; Shibutani S Cancer Res; 1999 May; 59(9):2091-5. PubMed ID: 10232593 [TBL] [Abstract][Full Text] [Related]
20. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides. Fan PW; Zhang F; Bolton JL Chem Res Toxicol; 2000 Jan; 13(1):45-52. PubMed ID: 10649966 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]