BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 22065775)

  • 1. Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents.
    Goloudina AR; Tanoue K; Hammann A; Fourmaux E; Le Guezennec X; Bulavin DV; Mazur SJ; Appella E; Garrido C; Demidov ON
    Proc Natl Acad Sci U S A; 2012 Jan; 109(2):E68-75. PubMed ID: 22065775
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xL ratio.
    Goloudina AR; Mazur SJ; Appella E; Garrido C; Demidov ON
    Cell Cycle; 2012 May; 11(10):1883-7. PubMed ID: 22544321
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The estrogen receptor alpha pathway induces oncogenic Wip1 phosphatase gene expression.
    Han HS; Yu E; Song JY; Park JY; Jang SJ; Choi J
    Mol Cancer Res; 2009 May; 7(5):713-23. PubMed ID: 19435816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
    Park JY; Song JY; Kim HM; Han HS; Seol HS; Jang SJ; Choi J
    Int J Biochem Cell Biol; 2012 Jun; 44(6):896-904. PubMed ID: 22405851
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy.
    Clausse V; Goloudina AR; Uyanik B; Kochetkova EY; Richaud S; Fedorova OA; Hammann A; Bardou M; Barlev NA; Garrido C; Demidov ON
    Cell Death Dis; 2016 Apr; 7(4):e2195. PubMed ID: 27077811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
    J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
    Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
    Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis.
    Ma X; Han J; Wu Q; Liu H; Shi S; Wang C; Wang Y; Xiao J; Zhao J; Jiang J; Wan C
    Toxicol Lett; 2015 May; 235(1):17-27. PubMed ID: 25791630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation.
    Song JY; Han HS; Sabapathy K; Lee BM; Yu E; Choi J
    J Biol Chem; 2010 Mar; 285(12):9067-76. PubMed ID: 20093361
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D.
    Castellino RC; De Bortoli M; Lu X; Moon SH; Nguyen TA; Shepard MA; Rao PH; Donehower LA; Kim JY
    J Neurooncol; 2008 Feb; 86(3):245-56. PubMed ID: 17932621
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
    Spinnler C; Hedström E; Li H; de Lange J; Nikulenkov F; Teunisse AF; Verlaan-de Vries M; Grinkevich V; Jochemsen AG; Selivanova G
    Cell Death Differ; 2011 Nov; 18(11):1736-45. PubMed ID: 21546907
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of Wild-Type p53-Induced Phosphatase 1 Confers Poor Prognosis of Patients with Nasopharyngeal Carcinoma.
    Sun GG; Zhang J; Ma XB; Wang YD; Cheng YJ; Hu WN
    Pathol Oncol Res; 2015 Apr; 21(2):283-91. PubMed ID: 25060857
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wip1 regulates the generation of new neural cells in the adult olfactory bulb through p53-dependent cell cycle control.
    Zhu YH; Zhang CW; Lu L; Demidov ON; Sun L; Yang L; Bulavin DV; Xiao ZC
    Stem Cells; 2009 Jun; 27(6):1433-42. PubMed ID: 19489034
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.
    Doucette TA; Yang Y; Pedone C; Kim JY; Dubuc A; Northcott PD; Taylor MD; Fults DW; Rao G
    Neurosurgery; 2012 Apr; 70(4):1003-10; discussion 1010. PubMed ID: 22037313
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Over-expression of wild-type p53-induced phosphatase 1 confers poor prognosis of patients with gliomas.
    Liang C; Guo E; Lu S; Wang S; Kang C; Chang L; Liu L; Zhang G; Wu Z; Zhao Z; Ma S; Wang L; Jiao BH
    Brain Res; 2012 Mar; 1444():65-75. PubMed ID: 22325093
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.
    Crescenzi E; Raia Z; Pacifico F; Mellone S; Moscato F; Palumbo G; Leonardi A
    J Biol Chem; 2013 Jun; 288(23):16212-16224. PubMed ID: 23612976
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.
    Brazina J; Svadlenka J; Macurek L; Andera L; Hodny Z; Bartek J; Hanzlikova H
    Cell Cycle; 2015; 14(3):375-87. PubMed ID: 25659035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways.
    Chen Z; Yi W; Morita Y; Wang H; Cong Y; Liu JP; Xiao Z; Rudolph KL; Cheng T; Ju Z
    Nat Commun; 2015 Apr; 6():6808. PubMed ID: 25879755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p53 Regulates LIF expression in human medulloblastoma cells.
    Baxter EW; Milner J
    J Neurooncol; 2010 May; 97(3):373-82. PubMed ID: 19907922
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to γ-radiation.
    Song JY; Ryu SH; Cho YM; Kim YS; Lee BM; Lee SW; Choi J
    Cell Death Dis; 2013 Aug; 4(8):e744. PubMed ID: 23907458
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.