BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 22067383)

  • 1. IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood.
    Sneller MC; Kopp WC; Engelke KJ; Yovandich JL; Creekmore SP; Waldmann TA; Lane HC
    Blood; 2011 Dec; 118(26):6845-8. PubMed ID: 22067383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates.
    Lugli E; Goldman CK; Perera LP; Smedley J; Pung R; Yovandich JL; Creekmore SP; Waldmann TA; Roederer M
    Blood; 2010 Oct; 116(17):3238-48. PubMed ID: 20631381
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques.
    Villinger F; Miller R; Mori K; Mayne AE; Bostik P; Sundstrom JB; Sugimoto C; Ansari AA
    Vaccine; 2004 Sep; 22(25-26):3510-21. PubMed ID: 15308379
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies.
    Dubois SP; Miljkovic MD; Fleisher TA; Pittaluga S; Hsu-Albert J; Bryant BR; Petrus MN; Perera LP; Müller JR; Shih JH; Waldmann TA; Conlon KC
    J Immunother Cancer; 2021 Apr; 9(4):. PubMed ID: 33883258
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.
    Conlon KC; Lugli E; Welles HC; Rosenberg SA; Fojo AT; Morris JC; Fleisher TA; Dubois SP; Perera LP; Stewart DM; Goldman CK; Bryant BR; Decker JM; Chen J; Worthy TA; Figg WD; Peer CJ; Sneller MC; Lane HC; Yovandich JL; Creekmore SP; Roederer M; Waldmann TA
    J Clin Oncol; 2015 Jan; 33(1):74-82. PubMed ID: 25403209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replication.
    Pallikkuth S; Rogers K; Villinger F; Dosterii M; Vaccari M; Franchini G; Pahwa R; Pahwa S
    Vaccine; 2011 Nov; 29(49):9229-38. PubMed ID: 21996099
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.
    Webb GM; Molden J; Busman-Sahay K; Abdulhaqq S; Wu HL; Weber WC; Bateman KB; Reed JS; Northrup M; Maier N; Tanaka S; Gao L; Davey B; Carpenter BL; Axthelm MK; Stanton JJ; Smedley J; Greene JM; Safrit JT; Estes JD; Skinner PJ; Sacha JB
    PLoS Pathog; 2020 Mar; 16(3):e1008339. PubMed ID: 32163523
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-15 increases effector memory CD8+ t cells and NK Cells in simian immunodeficiency virus-infected macaques.
    Mueller YM; Petrovas C; Bojczuk PM; Dimitriou ID; Beer B; Silvera P; Villinger F; Cairns JS; Gracely EJ; Lewis MG; Katsikis PD
    J Virol; 2005 Apr; 79(8):4877-85. PubMed ID: 15795273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NKTR-255 is a polymer-conjugated IL-15 with unique mechanisms of action on T and natural killer cells.
    Robinson TO; Hegde SM; Chang A; Gangadharan A; Rivas S; Madakamutil L; Zalevsky J; Miyazaki T; Schluns KS
    J Clin Invest; 2021 Oct; 131(19):. PubMed ID: 34375310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Safety and immunologic effects of IL-15 administration in nonhuman primates.
    Berger C; Berger M; Hackman RC; Gough M; Elliott C; Jensen MC; Riddell SR
    Blood; 2009 Sep; 114(12):2417-26. PubMed ID: 19605850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion.
    Conlon KC; Potter EL; Pittaluga S; Lee CR; Miljkovic MD; Fleisher TA; Dubois S; Bryant BR; Petrus M; Perera LP; Hsu J; Figg WD; Peer CJ; Shih JH; Yovandich JL; Creekmore SP; Roederer M; Waldmann TA
    Clin Cancer Res; 2019 Aug; 25(16):4945-4954. PubMed ID: 31142503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells.
    Zecher D; Li Q; Oberbarnscheidt MH; Demetris AJ; Shlomchik WD; Rothstein DM; Lakkis FG
    J Immunol; 2010 Jun; 184(12):6649-57. PubMed ID: 20483732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques.
    Berger C; Berger M; Beard BC; Kiem HP; Gooley TA; Riddell SR
    PLoS One; 2013; 8(2):e56268. PubMed ID: 23418547
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.
    Okoye A; Park H; Rohankhedkar M; Coyne-Johnson L; Lum R; Walker JM; Planer SL; Legasse AW; Sylwester AW; Piatak M; Lifson JD; Sodora DL; Villinger F; Axthelm MK; Schmitz JE; Picker LJ
    J Exp Med; 2009 Jul; 206(7):1575-88. PubMed ID: 19546246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation.
    Alpdogan O; Eng JM; Muriglan SJ; Willis LM; Hubbard VM; Tjoe KH; Terwey TH; Kochman A; van den Brink MR
    Blood; 2005 Jan; 105(2):865-73. PubMed ID: 15280205
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques.
    Halwani R; Boyer JD; Yassine-Diab B; Haddad EK; Robinson TM; Kumar S; Parkinson R; Wu L; Sidhu MK; Phillipson-Weiner R; Pavlakis GN; Felber BK; Lewis MG; Shen A; Siliciano RF; Weiner DB; Sekaly RP
    J Immunol; 2008 Jun; 180(12):7969-79. PubMed ID: 18523260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Initial antigen encounter programs CD8+ T cells competent to develop into memory cells that are activated in an antigen-free, IL-7- and IL-15-rich environment.
    Carrio R; Bathe OF; Malek TR
    J Immunol; 2004 Jun; 172(12):7315-23. PubMed ID: 15187107
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool.
    Melchionda F; Fry TJ; Milliron MJ; McKirdy MA; Tagaya Y; Mackall CL
    J Clin Invest; 2005 May; 115(5):1177-87. PubMed ID: 15841203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses.
    Mueller YM; Do DH; Altork SR; Artlett CM; Gracely EJ; Katsetos CD; Legido A; Villinger F; Altman JD; Brown CR; Lewis MG; Katsikis PD
    J Immunol; 2008 Jan; 180(1):350-60. PubMed ID: 18097036
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques.
    Okoye AA; Rohankhedkar M; Konfe AL; Abana CO; Reyes MD; Clock JA; Duell DM; Sylwester AW; Sammader P; Legasse AW; Park BS; Axthelm MK; Nikolich-Žugich J; Picker LJ
    J Immunol; 2015 Nov; 195(9):4292-305. PubMed ID: 26416281
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.