These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 22069330)

  • 21. Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity.
    Kaltenbach M; Emond S; Hollfelder F; Tokuriki N
    PLoS Genet; 2016 Oct; 12(10):e1006305. PubMed ID: 27716796
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Enzyme promiscuity: a mechanistic and evolutionary perspective.
    Khersonsky O; Tawfik DS
    Annu Rev Biochem; 2010; 79():471-505. PubMed ID: 20235827
    [TBL] [Abstract][Full Text] [Related]  

  • 23. New insights about enzyme evolution from large scale studies of sequence and structure relationships.
    Brown SD; Babbitt PC
    J Biol Chem; 2014 Oct; 289(44):30221-30228. PubMed ID: 25210038
    [TBL] [Abstract][Full Text] [Related]  

  • 24. How to Recruit a Promiscuous Enzyme to Serve a New Function.
    Copley SD; Newton MS; Widney KA
    Biochemistry; 2023 Jan; 62(2):300-308. PubMed ID: 35729117
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Optimal control of metabolic networks with saturable enzyme kinetics.
    Oyarzuun DA
    IET Syst Biol; 2011 Mar; 5(2):110-9. PubMed ID: 21405199
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Understanding the importance of protein structure to nature's routes for divergent evolution in TIM barrel enzymes.
    Wise EL; Rayment I
    Acc Chem Res; 2004 Mar; 37(3):149-58. PubMed ID: 15023082
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Engineering specialized metabolic pathways--is there a room for enzyme improvements?
    Bar-Even A; Salah Tawfik D
    Curr Opin Biotechnol; 2013 Apr; 24(2):310-9. PubMed ID: 23102865
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A network perspective on the evolution of metabolism by gene duplication.
    Díaz-Mejía JJ; Pérez-Rueda E; Segovia L
    Genome Biol; 2007; 8(2):R26. PubMed ID: 17326820
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Dynamics and constraints of enzyme evolution.
    Kaltenbach M; Tokuriki N
    J Exp Zool B Mol Dev Evol; 2014 Nov; 322(7):468-87. PubMed ID: 24522979
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Evolution of protein function, from a structural perspective.
    Todd AE; Orengo CA; Thornton JM
    Curr Opin Chem Biol; 1999 Oct; 3(5):548-56. PubMed ID: 10508675
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Divergence and convergence in enzyme evolution.
    Galperin MY; Koonin EV
    J Biol Chem; 2012 Jan; 287(1):21-28. PubMed ID: 22069324
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Enzyme promiscuity shapes adaptation to novel growth substrates.
    Guzmán GI; Sandberg TE; LaCroix RA; Nyerges Á; Papp H; de Raad M; King ZA; Hefner Y; Northen TR; Notebaart RA; Pál C; Palsson BO; Papp B; Feist AM
    Mol Syst Biol; 2019 Apr; 15(4):e8462. PubMed ID: 30962359
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Catalysing new reactions during evolution: economy of residues and mechanism.
    Bartlett GJ; Borkakoti N; Thornton JM
    J Mol Biol; 2003 Aug; 331(4):829-60. PubMed ID: 12909013
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence.
    Lundin E; Näsvall J; Andersson DI
    Front Microbiol; 2020; 11():588235. PubMed ID: 33154742
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Classification and Evolution of Enzyme Function.
    Martínez Cuesta S; Rahman SA; Furnham N; Thornton JM
    Biophys J; 2015 Sep; 109(6):1082-6. PubMed ID: 25986631
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolic flux correlations, genetic interactions, and disease.
    Veeramani B; Bader JS
    J Comput Biol; 2009 Feb; 16(2):291-302. PubMed ID: 19193147
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Evolution of the protein repertoire.
    Chothia C; Gough J; Vogel C; Teichmann SA
    Science; 2003 Jun; 300(5626):1701-3. PubMed ID: 12805536
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity.
    Fendt SM; Buescher JM; Rudroff F; Picotti P; Zamboni N; Sauer U
    Mol Syst Biol; 2010 Apr; 6():356. PubMed ID: 20393576
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Directed Evolution of Protein Catalysts.
    Zeymer C; Hilvert D
    Annu Rev Biochem; 2018 Jun; 87():131-157. PubMed ID: 29494241
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies.
    Furnham N; Dawson NL; Rahman SA; Thornton JM; Orengo CA
    J Mol Biol; 2016 Jan; 428(2 Pt A):253-267. PubMed ID: 26585402
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.