BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 22069692)

  • 1. The Discodermia calyx toxin calyculin a enhances cyclin D1 phosphorylation and degradation, and arrests cell cycle progression in human breast cancer cells.
    Edelson JR; Brautigan DL
    Toxins (Basel); 2011 Jan; 3(1):105-19. PubMed ID: 22069692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calyculin A from Discodermia calyx is a dual action toxin that blocks calcium influx and inhibits protein Ser/Thr phosphatases.
    Holy M; Brautigan DL
    Toxins (Basel); 2012 Oct; 4(10):940-54. PubMed ID: 23162706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein. PP2a regulates the activities of G(1) cyclin-dependent kinases.
    Yan Y; Mumby MC
    J Biol Chem; 1999 Nov; 274(45):31917-24. PubMed ID: 10542219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.
    Dynia DW; Steinmetz AG; Kocinsky HS
    Am J Physiol Renal Physiol; 2010 Mar; 298(3):F745-53. PubMed ID: 20015946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Calyculin: Nature's way of making the sponge-derived cytotoxin.
    Wakimoto T; Egami Y; Abe I
    Nat Prod Rep; 2016 Jun; 33(6):751-60. PubMed ID: 26923942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells.
    Park SB; Park GH; Song HM; Son HJ; Um Y; Kim HS; Jeong JB
    BMC Complement Altern Med; 2017 Sep; 17(1):445. PubMed ID: 28870200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The involvement of cyclin D1 degradation through GSK3β-mediated threonine-286 phosphorylation-dependent nuclear export in anti-cancer activity of mulberry root bark extracts.
    Eo HJ; Park GH; Jeong JB
    Phytomedicine; 2016 Feb; 23(2):105-13. PubMed ID: 26926171
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Everolimus induces G
    Chen G; Ding XF; Bouamar H; Pressley K; Sun LZ
    Am J Physiol Cell Physiol; 2019 Aug; 317(2):C244-C252. PubMed ID: 31116586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.
    Resjö S; Oknianska A; Zolnierowicz S; Manganiello V; Degerman E
    Biochem J; 1999 Aug; 341 ( Pt 3)(Pt 3):839-45. PubMed ID: 10417351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multidrug-resistant human KB carcinoma cells are highly resistant to the protein phosphatase inhibitors okadaic acid and calyculin A. Analysis of potential mechanisms involved in toxin resistance.
    Chambers TC; Raynor RL; Kuo JF
    Int J Cancer; 1993 Jan; 53(2):323-7. PubMed ID: 8093882
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer.
    Gwak H; Kim Y; An H; Dhanasekaran DN; Song YS
    Mol Carcinog; 2017 Feb; 56(2):349-358. PubMed ID: 27128966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of natural toxins with inhibitory activity against serine/threonine protein phosphatases.
    Honkanen RE; Codispoti BA; Tse K; Boynton AL; Honkanan RE
    Toxicon; 1994 Mar; 32(3):339-50. PubMed ID: 8016855
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GSK3β-dependent cyclin D1 and cyclin E1 degradation is indispensable for NVP-BEZ235 induced G0/G1 arrest in neuroblastoma cells.
    Liu SL; Liu Z; Zhang LD; Zhu HQ; Guo JH; Zhao M; Wu YL; Liu F; Gao FH
    Cell Cycle; 2017; 16(24):2386-2395. PubMed ID: 28980866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-cancer activity of
    Park GH; Song HM; Kim YS; Jeon Y; Koo JS; Jeong HJ; Jeong JB
    Pharmazie; 2017 Jun; 72(6):348-354. PubMed ID: 29442024
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin.
    Favre B; Turowski P; Hemmings BA
    J Biol Chem; 1997 May; 272(21):13856-63. PubMed ID: 9153244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.
    Wakimoto T; Egami Y; Nakashima Y; Wakimoto Y; Mori T; Awakawa T; Ito T; Kenmoku H; Asakawa Y; Piel J; Abe I
    Nat Chem Biol; 2014 Aug; 10(8):648-55. PubMed ID: 24974231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wogonin inhibits cell cycle progression by activating the glycogen synthase kinase-3 beta in hepatocellular carcinoma.
    Hong M; Almutairi MM; Li S; Li J
    Phytomedicine; 2020 Mar; 68():153174. PubMed ID: 31991293
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of protein phosphatase type 1 and 2A attenuate phosphatidylinositol metabolism and Ca(2+)-transients in human platelets. Role of a cdc2-related protein kinase.
    Lerea KM
    Biochemistry; 1992 Jul; 31(28):6553-61. PubMed ID: 1321663
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insight into binding of calyculin A to protein phosphatase 1: isolation of hemicalyculin a and chemical transformation of calyculin A.
    Wakimoto T; Matsunaga S; Takai A; Fusetani N
    Chem Biol; 2002 Mar; 9(3):309-19. PubMed ID: 11927256
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silymarin induces cyclin D1 proteasomal degradation via its phosphorylation of threonine-286 in human colorectal cancer cells.
    Eo HJ; Park GH; Song HM; Lee JW; Kim MK; Lee MH; Lee JR; Koo JS; Jeong JB
    Int Immunopharmacol; 2015 Jan; 24(1):1-6. PubMed ID: 25479723
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.