BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 22072743)

  • 1. BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein.
    Chiappetta G; Basile A; Arra C; Califano D; Pasquinelli R; Barbieri A; De Simone V; Rea D; Giudice A; Pezzullo L; De Laurenzi V; Botti G; Losito S; Conforti D; Turco MC
    J Clin Endocrinol Metab; 2012 Jan; 97(1):E115-20. PubMed ID: 22072743
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.
    Chiappetta G; Ammirante M; Basile A; Rosati A; Festa M; Monaco M; Vuttariello E; Pasquinelli R; Arra C; Zerilli M; Todaro M; Stassi G; Pezzullo L; Gentilella A; Tosco A; Pascale M; Marzullo L; Belisario MA; Turco MC; Leone A
    J Clin Endocrinol Metab; 2007 Mar; 92(3):1159-63. PubMed ID: 17164298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1.
    Du ZX; Zhang HY; Meng X; Gao YY; Zou RL; Liu BQ; Guan Y; Wang HQ
    J Cell Physiol; 2009 Mar; 218(3):631-7. PubMed ID: 19006120
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma.
    Altmann A; Markert A; Askoxylakis V; Schöning T; Jesenofsky R; Eisenhut M; Haberkorn U
    J Nucl Med; 2012 Nov; 53(11):1764-71. PubMed ID: 23055533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Knockdown of S100A4 blocks growth and metastasis of anaplastic thyroid cancer cells in vitro and in vivo.
    Zhang K; Yu M; Hao F; Dong A; Chen D
    Cancer Biomark; 2016 Sep; 17(3):281-291. PubMed ID: 27802204
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tunicamycin induces paraptosis potentiated by inhibition of BRAFV600E in FRO anaplastic thyroid carcinoma cells.
    Kim SH; Shin HY; Kim YS; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
    Anticancer Res; 2014 Sep; 34(9):4857-68. PubMed ID: 25202067
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
    Ouyang B; Knauf JA; Smith EP; Zhang L; Ramsey T; Yusuff N; Batt D; Fagin JA
    Clin Cancer Res; 2006 Mar; 12(6):1785-93. PubMed ID: 16551863
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BRAF is a therapeutic target in aggressive thyroid carcinoma.
    Salvatore G; De Falco V; Salerno P; Nappi TC; Pepe S; Troncone G; Carlomagno F; Melillo RM; Wilhelm SM; Santoro M
    Clin Cancer Res; 2006 Mar; 12(5):1623-9. PubMed ID: 16533790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LncRNA NEAT1 enhances the resistance of anaplastic thyroid carcinoma cells to cisplatin by sponging miR‑9‑5p and regulating SPAG9 expression.
    Yan P; Su Z; Zhang Z; Gao T
    Int J Oncol; 2019 Nov; 55(5):988-1002. PubMed ID: 31485599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations.
    Quiros RM; Ding HG; Gattuso P; Prinz RA; Xu X
    Cancer; 2005 Jun; 103(11):2261-8. PubMed ID: 15880523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways.
    Rapino F; Jung M; Fulda S
    Oncogene; 2014 Mar; 33(13):1713-24. PubMed ID: 23644654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells.
    Sala E; Mologni L; Truffa S; Gaetano C; Bollag GE; Gambacorti-Passerini C
    Mol Cancer Res; 2008 May; 6(5):751-9. PubMed ID: 18458053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effects of the mitogen-activated protein kinase kinase inhibitor CI-1040 on the proliferation and tumor growth of thyroid cancer cells with BRAF or RAS mutations.
    Liu D; Liu Z; Jiang D; Dackiw AP; Xing M
    J Clin Endocrinol Metab; 2007 Dec; 92(12):4686-95. PubMed ID: 17911174
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcriptional upregulation of BAG3 upon proteasome inhibition.
    Wang HQ; Liu HM; Zhang HY; Guan Y; Du ZX
    Biochem Biophys Res Commun; 2008 Jan; 365(2):381-5. PubMed ID: 17996194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer.
    Nucera C; Nehs MA; Nagarkatti SS; Sadow PM; Mekel M; Fischer AH; Lin PS; Bollag GE; Lawler J; Hodin RA; Parangi S
    Oncologist; 2011; 16(3):296-309. PubMed ID: 21355020
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
    Ball DW; Jin N; Rosen DM; Dackiw A; Sidransky D; Xing M; Nelkin BD
    J Clin Endocrinol Metab; 2007 Dec; 92(12):4712-8. PubMed ID: 17878251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase-dependent cleavage of BAG3 in proteasome inhibitors-induced apoptosis in thyroid cancer cells.
    Du ZX; Meng X; Zhang HY; Guan Y; Wang HQ
    Biochem Biophys Res Commun; 2008 May; 369(3):894-8. PubMed ID: 18325327
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CLM29 and CLM24, pyrazolopyrimidine derivatives, have antitumoral activity in vitro in anaplastic thyroid cancer, with or without BRAF mutation.
    Fallahi P; Ferrari SM; La Motta C; Materazzi G; Bocci G; Da Settimo F; Miccoli P; Antonelli A
    Endocrine; 2016 Jul; 53(1):136-44. PubMed ID: 26286966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.
    Minoia M; Boncoraglio A; Vinet J; Morelli FF; Brunsting JF; Poletti A; Krom S; Reits E; Kampinga HH; Carra S
    Autophagy; 2014 Sep; 10(9):1603-21. PubMed ID: 25046115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aberrant BRAF splicing as an alternative mechanism for oncogenic B-Raf activation in thyroid carcinoma.
    Baitei EY; Zou M; Al-Mohanna F; Collison K; Alzahrani AS; Farid NR; Meyer B; Shi Y
    J Pathol; 2009 Apr; 217(5):707-15. PubMed ID: 19156774
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.